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dc.contributor.authorOse, Jennifer
dc.contributor.authorFortner, Renée T
dc.contributor.authorSchock, Helena
dc.contributor.authorPeeters, Petra H.
dc.contributor.authorOnland-Moret, N. Charlotte
dc.contributor.authorBueno-de-Mesquita, H. Bas
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorGram, Inger Torhild
dc.contributor.authorOvervad, Kim
dc.contributor.authorTjønneland, Anne
dc.contributor.authorDossus, Laure
dc.contributor.authorFournier, Agnes
dc.contributor.authorBaglietto, Laura
dc.contributor.authorTrichopoulou, Antonia
dc.contributor.authorBenetou, Vassiliki
dc.contributor.authorTrichopoulos, Dimitrios
dc.contributor.authorBoeing, Heiner
dc.contributor.authorMasala, Giovanna
dc.contributor.authorKrogh, Vittorio
dc.contributor.authorMatiello, Amalia
dc.contributor.authorTumino, Rosaria
dc.contributor.authorPopovic, Maja
dc.contributor.authorObón-Santacana, Mireia
dc.contributor.authorLarrañaga, Nerea
dc.contributor.authorArdanaz, Eva
dc.contributor.authorSánchez, María-José
dc.contributor.authorMenéndez, Virginia
dc.contributor.authorChirlaque, María-Dolores
dc.contributor.authorTravis, Ruth C.
dc.contributor.authorKhaw, Kay-Tee
dc.contributor.authorBrändstedt, Jenny
dc.contributor.authorIdahl, Annika
dc.contributor.authorLundin, Eva
dc.contributor.authorRinaldi, Sabina
dc.contributor.authorKuhn, Elisabetta
dc.contributor.authorRomieu, Isabelle
dc.contributor.authorGunter, Marc J.
dc.contributor.authorMerritt, Melissa A.
dc.contributor.authorRiboli, Elio
dc.contributor.authorKaaks, Rudolf
dc.date.accessioned2022-05-02T07:06:07Z
dc.date.available2022-05-02T07:06:07Z
dc.date.issued2014-11-04
dc.description.abstractBackground: Prospective studies on insulin-like growth factor I (IGF-I) and epithelial ovarian cancer (EOC) risk are inconclusive. Data suggest risk associations vary by tumour characteristics.<p> <p>Methods: We conducted a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate IGF-I concentrations and EOC risk by tumour characteristics (n ¼ 565 cases). Multivariable conditional logistic regression models were used to estimate associations.<p> <p>Results: We observed no association between IGF-I and EOC overall or by tumour characteristics.<p> <p>Conclusions: In the largest prospective study to date was no association between IGF-I and EOC risk. Pre-diagnostic serum IGF-I concentrations may not influence EOC risk.en_US
dc.identifier.citationOse J, Fortner RT, Schock H, Peeters PH, Onland-Moret NC, Bueno-de-Mesquita HB, Weiderpass E, Gram IT, Overvad K, Tjønneland A, Dossus L, Fournier A, Baglietto L, Trichopoulou A, Benetou V, Trichopoulos D, Boeing H, Masala G, Krogh V, Matiello A, Tumino R, Popovic, Obón-Santacana M, Larrañaga N, Ardanaz E, Sánchez M, Menéndez, Chirlaque M, Travis RC, Khaw K, Brändstedt, Idahl A, Lundin E, Rinaldi S, Kuhn, Romieu I, Gunter MJ, Merritt, Riboli E, Kaaks R. Insulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohort. British Journal of Cancer. 2015;112(1):162-166en_US
dc.identifier.cristinIDFRIDAID 1240793
dc.identifier.doi10.1038/bjc.2014.566
dc.identifier.issn0007-0920
dc.identifier.issn1532-1827
dc.identifier.urihttps://hdl.handle.net/10037/24962
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.relation.journalBritish Journal of Cancer
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7-IDEAS-ERC/232997/EU/TRANSCRIPTOMICS IN CANCER EPIDEMIOLOGY/TICE/en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2015 Cancer Research UK.en_US
dc.titleInsulin-like growth factor I and risk of epithelial invasive ovarian cancer by tumour characteristics: Results from the EPIC cohorten_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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