dc.contributor.author | Konglevoll, Dina Moxness | |
dc.contributor.author | Hjartåker, Anette | |
dc.contributor.author | Hopstock, Laila Arnesdatter | |
dc.contributor.author | Strand, Bjørn Heine | |
dc.contributor.author | Thoresen, Magne | |
dc.contributor.author | Andersen, Lene Frost | |
dc.contributor.author | Carlsen, Monica Hauger | |
dc.date.accessioned | 2022-08-19T08:48:04Z | |
dc.date.available | 2022-08-19T08:48:04Z | |
dc.date.issued | 2022-03-01 | |
dc.description.abstract | BACKGROUND: Protein intake is suggested as an important dietary
factor in the prevention of frailty, however, the infuence of lifelong
intake remains unclear.<p>
<p>OBJECTIVES: The present study investigated the relationship between
daily protein intake and patterns of protein intake over 21 years and the
risk of pre-frailty/frailty.
<p>DESIGN: Prospective cohort study.
<p>SETTING: The population-based Tromsø Study in Tromsø municipality,
Norway.
PARTICIPANTS: In total, 1,906 women and 1,820 men aged >45 years
in 1994 who participated in both Tromsø4 (1994–95) and Tromsø7
(2015–16).
<p>MEASUREMENTS: Frailty status in Tromsø7 was measured according
to Fried’s phenotype, classifying participants as “robust” (frailty
components present: 0), “pre-frail” (1–2) or “frail” (>3). Daily intake of
protein was estimated from self-reported habitual dietary intake using
food frequency questionnaires and assessed as grams per kilogram
bodyweight (g/kg BW) and per megajoule energy intake (g/MJ). The
protein–frailty association was assessed via longitudinal and crosssectional multivariable logistic regression analyses.
<p>RESULTS: The prevalence of pre-frailty and frailty in this study was
27% and 1.0%, respectively. Longitudinal analysis showed that the
odds of pre-frailty/frailty decreased by 57% (odds ratio (OR) = 0.43,
95% confdence interval (CI) = 0.31;0.58, p<0.001) with the increase in
intake of one additional gram of dietary protein per kg BW. The results
obtained from cross-sectional analysis were similar. Tracking analysis
showed that, compared to a stable high intake of protein in g/kg BW
over time, other patterns of protein intake increased the risk of prefrailty/frailty. No associations were found between intake of protein in
g/MJ and pre-frailty/frailty.
<p>CONCLUSIONS: Intake of protein in g/kg BW both in mid-life and
later in life was inversely associated with pre-frailty/frailty in older
adults. This emphasizes the importance of an adequate protein intake to
facilitate healthy ageing in Norwegian older adults. | en_US |
dc.identifier.citation | Konglevoll DM, Hjartåker A, Hopstock LA, Strand BH, Thoresen M, Andersen, Carlsen MHC. Protein Intake and the Risk of Pre-Frailty and Frailty in Norwegian Older Adults. The Tromsø Study 1994–2016. Journal of Frailty & Aging (JFA). 2022:1-11 | en_US |
dc.identifier.cristinID | FRIDAID 2008251 | |
dc.identifier.doi | 10.14283/jfa.2022.16 | |
dc.identifier.issn | 2260-1341 | |
dc.identifier.issn | 2273-4309 | |
dc.identifier.uri | https://hdl.handle.net/10037/26291 | |
dc.language.iso | eng | en_US |
dc.publisher | Springer | en_US |
dc.relation.journal | Journal of Frailty & Aging (JFA) | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2022 The Author(s) | en_US |
dc.title | Protein Intake and the Risk of Pre-Frailty and Frailty in Norwegian Older Adults. The Tromsø Study 1994–2016 | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |