Vis enkel innførsel

dc.contributor.authorSeternes, Tore
dc.contributor.authorPoppe, Trygve T
dc.contributor.authorBøgwald, Jarl
dc.contributor.authorLynghammar, Arve
dc.contributor.authorDalmo, Roy Ambli
dc.date.accessioned2023-12-20T12:09:14Z
dc.date.available2023-12-20T12:09:14Z
dc.date.issued2023-11-28
dc.description.abstractThe scavenger endothelial cells (SECs) of vertebrates are an important class of endocytic cells responsible for clearance of foreign and physiological waste macromolecules, partitioning in the immune system, functioning as a cellular powerplant by producing high energy metabolites like lactate and acetate. All animal phyla possess SECs, but the tissue localization of SECs has only been investigated in a limited number of species. By using a specific ligand for scavenger receptors (formalin treated bovine serum albumin), the study revealed that in all tetrapod species (amphibia, reptiles, birds and mammals) the SECs were found lining the sinusoids of the liver. No SECs were found in the liver of any of the bony fishes (Osteichthyes) investigated. Interestingly, we found the SECs not only to be located in the heart of marine species but also in some freshwater species such as Lota lota, Percichthys trucha and Perca fluviatilis. In some fish species, the SECs were found both in the heart and/or kidney in a number of marine and freshwater fishes, whereas in some marine, diadromous and freshwater fishes the SECs were confined only to the kidney tissue. However, from these results it can be suggested that there is neither a clear phylogenetic trend when it came to anatomical localization of SECs nor any pattern in terms of habitat (salinity preferences).en_US
dc.identifier.citationSeternes, Poppe, Bøgwald, Lynghammar, Dalmo. Anatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes). Fish and Shellfish Immunology. 2023en_US
dc.identifier.cristinIDFRIDAID 2213891
dc.identifier.doi10.1016/j.fsi.2023.109250
dc.identifier.issn1050-4648
dc.identifier.issn1095-9947
dc.identifier.urihttps://hdl.handle.net/10037/32176
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalFish and Shellfish Immunology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleAnatomical distribution of scavenger endothelial cells in bony fishes (Osteichthyes)en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)