Objective: Evidence-based personality disorder (PD) treatments are dominated by interventions targeting Borderline PD, although clinical populations characteristically include different PD features and severity. Personality functioning is a new concept intended to capture common features across PDs. This study aimed to investigate longitudinal improvement of personality functioning in a clinical ...

In 2009 stroke care in the University Hospital of Northern Norway was reorganized. Until that year the hospital provided stroke care in two separate locations: patients 75 years and older were treated in the Geriatric Unit of the Medical Department while those younger were treated in the Neurological Department. Waiting times in the emergency unit were long, especially for the older patients. With ...

Background: Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed attention has arisen due to recent advancements in cancer diagnostics including access to high-throughput sequencing of tumour tissue. Targeted therapies interfering with cancer ...

Objectives: Machine learning (ML) and natural language processing have great potential to improve effciency and accuracy in diagnosis, treatment recommendations, predictive interventions, and scarce resource allocation within psychiatry. Researchers often conceptualize such an approach as operating in isolation without much need for human involvement, yet it remains crucial to harness human-inthe-loop ...

Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and morbidity in both men and women. Sex, however, affects several aspects of IHD, including pathophysiology, incidence, clinical presentation, diagnosis as well as treatment and outcome. Several diseases or risk factors frequently associated with IHD can modify cellular signalling cascades, thus affecting ischaemia/reperfusion ...

Background: Digital tools for social communication have been deployed in care facilities during the COVID-19 pandemic to facilitate social connectedness between older people and their next of kin in a safe manner. This study explores how and why health care professionals facilitate the ad hoc and prompt use of a technology for social communication, known as KOMP, in care facilities in western ...

Dette mastergradsarbeidet handler om hvordan man kan forstå det å ha kreftsykdom ut fra hvordan sykdommen snakkes, eller ikke snakkes om i samiske samfunn. Det er i dagens kreftomsorg et sterkt fokus på å hjelpe de som rammes av kreft til å mestre krisen dette kan oppleves som. Samtale; det å snakke om og sette ord på følelser, tanker og reaksjoner anses som den viktigste metoden i krisebearbeidingen. ...

Plastic laboratory materials are found to affect vital parameters of the waterflea Daphnia magna. The main responsible factor is defined as “newness” of the materials. Juvenile D. magna were raised individually in; a) new laboratory-standard 50 ml polypropylene tubes, and; b) identical tubes which had been washed and aerated for several weeks. Newness had significant effects on growth and fecundity ...

The GABA_B receptor (GABA_B-R) is a heterodimeric class C G protein-coupled receptor comprised of the GABA_B1a/b and GABA_B2 subunits. The endogenous orthosteric agonist γ-amino-butyric acid (GABA) binds within the extracellular Venus flytrap (VFT) domain of the GABA_B1a/b subunit. The receptor is associated with numerous neurological and ...