Now showing items 1384-1403 of 5481

    • Ebola, fra neglisjert sykdom til midtpunkt i nyhetsbildet. En retrospektiv studie av ebola-epidemien 2014-2015 

      Aalstad, Marthe (Master thesis; Mastergradsoppgave, 2017-09-25)
      Innledning: I denne oppgaven tok vi utgangspunkt i ebola virus disease (EVD)-epidemien som rammet Vest-Afrika i 2014-2015. En epidemi som rammet flere land i løpet av få måneder, ble raskt det største EVD-utbruddet i historien og førte til stor bekymring, ikke bare blant befolkningen i Vest-Afrika, men også over store deler av verden. Jeg lurte derfor på om det fantes en sammenheng mellom epidemiologiske ...
    • Eclampsia, maternal deaths, and hypertensive diseases of pregnancy and long term maternal health risk 

      Andersgaard, Alice Beathe (Doctoral thesis; Doktorgradsavhandling, 2011-11-10)
      Det er viktig å kartlegge og gjennomgå alvorlige hendelser i forbindelse med svangerskap og fødsel. I dette arbeidet er det satt fokus på to dramatiske komplikasjoner; kvinner som har svangerskapsforgiftning (preeklampsi) og får kramer (eklampsi) og kvinner som dør i forbindelse med svangerskap og fødsel. I samarbeid med kolleger i Norge, Danmark og Sverige gjennomførte vi en registrering av ...
    • Ecological study on the use of hormonal contraception, abortions and births among teenagers in the Nordic countries 

      Hognert, Helena; Skjeldestad, Finn Egil; Gemzell-Danielsson, Kristina; Heikinheimo, Oskari; Milsom, Ian; Lidegaard, Øjvind; Lindh, Ingela (Journal article; Peer reviewed, 2018-10-30)
      Objectives <br>Compare hormonal contraceptive use, birth and abortion rates among teenagers in the Nordic countries. A secondary aim was to explore plausible explanations for possible differences between countries.<br> Design <br> Ecological study using national registry data concerning births and abortions among all women aged 15–19 years residing in Denmark, Finland, Iceland, Norway and Sweden ...
    • Ecotoxicological assessment of Roundup-ready soybean agriculture investigated in a D. magna model 

      Cuhra, Marek (Doctoral thesis; Doktorgradsavhandling, 2015-06-09)
      Transgenic glyphosate tolerant soybeans are constituents of an industrial production system with specific agricultural practices and supplementary agrochemicals as interwoven additional elements. Thus the material produced should not be seen as an isolated product of a specific modified genotype but rather as a product of a tailored agriculture system. This globally dominant crop has been in open ...
    • Ectopic and normal maxillary canine eruption: maxillary incisor root resorption and interceptive treatment 

      Hadler-Olsen, Sigurd (Doctoral thesis; Doktorgradsavhandling, 2019-10-25)
      Ektopisk erupsjon av overkjevens hjørnetenner berører 1-5 prosent av barn, og er en tilstand som kan føre til alvorlige skader på nabotenner samt omfattende tannbehandling. Det vitenskapelige grunnlaget for behandling av ektopiske hjørnetenner er begrenset. Målet med denne PhD-avhandlingen var å skaffe ny kunnskap om omfanget av rotresorpsjon på overkjevens fortenner, den vanligste bivirkningen, ...
    • Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn 

      Hallstensen, Randi; Bergseth, Grete; Foss, Stian; Jæger, Steinar; Gedde-Dahl, Thobias; Holt, jan; Christiansen, Dorte; Lau, Corinna; Brekke, Ole Lars; Armstrong, Elina; Stefanovic, Vedran; Andersen, Jan Terje; Sandlie, Inger; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-13)
      Eculizumab is a humanized IgG2/4 chimeric anti-complement C5 antibody used to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) or atypical hemolytic uremic syndrome. The aim of this study was to evaluate whether or not the complement activity in newborns from pregnant women who receive eculizumab is impaired. A novel eculizumab-C5 complex (E-C5) specific assay was developed and ...
    • Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses 

      Nilsson, Per; Thomas, Anub Mathew; Bergseth, Grete; Gustavsen, Alice; Volokhina, Elena B.; van den Heuvel, Lambertus P.; Barratt-Due, Andreas; Mollnes, Tom Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-10)
      The complement system has obtained renewed clinical focus due to increasing number of patients treated with eculizumab, a monoclonal antibody inhibiting cleavage of C5 into C5a and C5b. The FDA approved indications are paroxysmal nocturnal haemoglobinuria and atypical haemolytic uremic syndrome, but many other diseases are candidates for complement inhibition. It has been postulated that eculizumab ...
    • Education and health and well-being: direct and indirect effects with multiple mediators and interactions with multiple imputed data in Stata 

      Sheikh, Mashhood Ahmed; Abelsen, Birgit; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-12)
      <p><i>Background</i>: Previous methods for assessing mediation assume no multiplicative interactions. The inverse odds weighting (IOW) approach has been presented as a method that can be used even when interactions exist. The substantive aim of this study was to assess the indirect effect of education on health and well-being via four indicators of adult socioeconomic status (SES): income, management ...
    • Education of dentists: a comparison of the three dental programs in Norway 

      Mehus, Kristin Elise; Pedersen, Ragnar (Master thesis; Mastergradsoppgave, 2011-06-08)
      En sammenligning av de tre utdanningsprogrammene i odontologi i Norge basert på studieplaner og styrende dokumenter.
    • Educational Footprints and Psychosocial Factors in Multicultural Contexts in Arctic Norway. A Cohort and Registry Data Study among Sami and Non-Sami Students, 2003–2012 

      Bania, Elisabeth Valmyr (Doctoral thesis; Doktorgradsavhandling, 2017-02-17)
      Utdanning er viktig i alles liv, og i stadig større grad. Formålet med dette forskningsprosjektet var å undersøke sammenhengen mellom utdanningsplaner, skolefrafall i videregående skole og høgere utdanning. Ungdomshelseundersøkelsen i Nord-Norge (UHNN) var en langsgående undersøkelse som fulgte ungdom fra hele Nord-Norge fra 10.klasse og 10 år fram i tid. En rekke forhold ved 10.klassingers liv ...
    • The educational gradient in cardiovascular risk factors: impact of shared family factors in 228,346 Norwegian siblings 

      Ariansen, Inger Kristine; Mortensen, Laust Hvas; Graff-Iversen, Sidsel; Stigum, Hein; Kjøllesdal, Marte Karoline Råberg; Næss, Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-30)
      <p><b>Background:</b> Various indicators of childhood socioeconomic position have been related to cardiovascular disease (CVD) risk in adulthood. We investigated the impact of shared family factors on the educational gradient in midlife CVD risk factors by assessing within sibling similarities in the gradient using a discordant sibling design.</p> <p><b>Methods:</b> Norwegian health survey data ...
    • The educational gradient in premature cardiovascular mortality: Examining mediation by risk factors in cohorts born in the 1930s, 1940s and 1950s 

      Ariansen, Inger; Strand, Bjørn Heine; Kjøllesdal, Marte Karoline Råberg; Steingrímsdóttir, Ólöf Anna; Mortensen, Laust Hvas; Stigum, Hein; Graff-Iversen, Sidsel; Næss, Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-28)
      <i>Aims</i>: Educational inequality in cardiovascular disease and in modifiable risk factors changes over time and between birth cohorts. We aimed to assess how cardiovascular disease risk factors mediate educational differences in premature cardiovascular disease mortality and how this varies over birth cohorts and sex.<p> <p><i>Methods</i>: We followed 360,008 40–45-year-olds born in the ...
    • EEG-based effective connectivity distinguishes between unresponsive states with and without report of conscious experience and correlates with brain complexity 

      Bremnes, Thomas René; Juel, B.E.; Gosseries, O.; Rosanova, M.; Boly, M.; Laureys, S.; Larsson, P.G.; Massimini, M.; Storm, Johan Frederik (Master thesis; Mastergradsoppgave, 2017-11-01)
      Objective methods for distinguishing conscious from unconscious states in humans are of key importance for clinical evaluation of general anesthesia and patients with disorders or consciousness. Here, we test the generalizability of a DTF-based algorithm - a measure of effective connectivity - as an objective measure of conscious experience during anesthesia and correlate it with a well-tested index ...
    • Effect and accuracy of emergency dispatch telephone guidance to bystanders in trauma: post-hoc analysis of a prospective observational study 

      Bakke, Håkon Kvåle; Steinvik, Tine; Ruud, Håkon; Wisborg, Torben (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-07)
      Background:<br>Emergency medical communication centres (EMCCs) dispatch and allocate ambulance resources, and provide first-aid guidance to on-scene bystanders. We aimed to 1) evaluate whether dispatcher guidance improved bystander first aid in trauma, and 2) to evaluate whether dispatchers and on-scene emergency medical services (EMS) crews identified the same first aid measures as indicated.<br> ...
    • Effect of 8, 9-epoxy eicosapentaenoic acid on the growth of MCF-7 cells 

      Dahlheim, Anne-Helene (Master thesis; Mastergradsoppgave, 2008-05)
      ABSTRACT Epidemiologic studies have indicated that n-3 polyunsaturated fatty acids (PUFAs) supplementation may reduce the incidence of breast cancer, also in vivo and in vitro studies have shown that n-3 PUFAs have an inhibitory effect on breast cancer cells. One important n-3 PUFA are eiocosapentaenoic acid (EPA), which are metabolized to five regioisomeric epoxyeicosatetraenoic acids (epoxy-EPAs) ...
    • Effect of 8,9-epoxy eicosapentaenoic acid on human breast cancer cell line MDA-MB-231 

      Austreid, Ingunn (Master thesis; Mastergradsoppgave, 2008-05)
      Studies have shown that fatty acids from fish and fish oils, like eicosapentaenoic acid (EPA) and docosapentaenoic acid (DHA) may have a beneficial role in cancer by inhibiting proliferation or inducing apoptosis of the cancer cells. Several mechanisms involving different metabolites (eicosanoids) of the fatty acids have been suggested for the anti-cancer actions, but the detailed effects are still ...
    • Effect of a Fracture Liaison Service on the Rate of Subsequent Fracture Among Patients With a Fragility Fracture in the Norwegian Capture the Fracture Initiative (NoFRACT) 

      Andreasen, Camilla; Solberg, Lene Bergendal; Basso, Trude; Borgen, Tove Tveitan; Dahl, Cecilie; Wisløff, Torbjørn; Hagen, Gunhild; Apalset, Ellen M; Gjertsen, Jan-Erik; Figved, Wender; Hübschle, Lars Michael; Stutzer, Jens-Meinhard; Elvenes, Jan; Joakimsen, Ragnar Martin; Syversen, Unni; Eriksen, Erik Fink; Nordsletten, Lars; Frihagen, Frede Jon; Omsland, Tone Kristin; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-07)
      <p><i>Importance</i>: Fragility fracture is a major health issue because of the accompanying morbidity, mortality, and financial cost. Despite the high cost to society and personal cost to affected individuals, secondary fracture prevention is suboptimal in Norway, mainly because most patients with osteoporotic fractures do not receive treatment with antiosteoporotic drugs after fracture ...
    • Effect of Angiotensin II on the Left Ventricular Function in a Near-Term Fetal Sheep with Metabolic Acidemia 

      Acharya, Ganesh; Huhta, James; How, Ole-Jakob (Journal article; Tidsskriftartikkel, 2011)
    • The effect of cell death in the initiation of lupus nephritis 

      Fenton, Kristin Andreassen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01)
    • The Effect of Cognitive–Behavioral Therapy as an Antidepressive Treatment Is Falling: Reply to Ljòtsson et al. (2017) and Cristea et al. (2017) 

      Friborg, Oddgeir; Johnsen, Tom Johan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03)
      This article critically reassesses the nonlinear reanalysis by Ljótsson, Hedman, Mattsson, and Andersson (2017) and reviews Cristea et al.’s (2017) extension of our original meta-analysis (Johnsen & Friborg, 2015) reporting a decline in the effects of cognitive–behavioral therapy (CBT) for treating unipolar depression. Ljótsson et al. fitted a piecewise meta-regression model to the data, indicating ...