Alterations in microRNAs (miRNAs) expression are causative in the initiation and progression of human cancers. The molecular events responsible for the widespread differential expression of miRNAs in malignancy are exemplified by their location in cancer-associated genomic regions, epigenetic mechanisms, transcriptional dysregulation, chemical modifications and editing, and alterations in miRNA ...

Background This study has explored the classification of bipolar disorder in psychiatric hospital. A review of the literature reveals that there is a need for studies using stringent methodological approaches. Methods 480 first-time admitted patients to psychiatric hospital were found eligible and 271 of these gave written informed consent. The study sample was comprised of 250 patients (52%) ...

In this literature study, a classification of severe discolorations and a summary over the options for different dental treatments have been described. Various causes of these severe discolorations are presented and how the mechanisms behind tooth discolorations affect the outcome of a treatment or treatment options. Finally, the aesthetic outcome of a possible bleaching treatment of the different ...

<p><i>Background - </i>The clenched fist syndrome/psycho-flexed hand, first described in the early 1980s, has not yet entered the major psychiatric textbooks. Curiously, the phenomenon has been illuminated mainly in journals and textbooks on hand surgery. There is a need to examine, describe, and understand this syndrome from a psychiatric perspective. <p><i>Case presentation - </i>We present a ...

In 2007, the Intergovernmental Panel on Climate Change (IPCC) presented a large amount of evidence about global warming and the impact of human activities on global climate change. The Lancet Commission have identified a number of ways in which climate change can influence human health: lack of food and safe drinking water, poor sanitation, population migration, changing disease patterns and ...

Objectives. Patients previously treated with coronary stents may suffer an acute coronary syndrome (ACS) without any evidence of thrombus formation on coronary angiography (CAG). This may be due to partial, nonocclusive stent thrombosis with microembolization. In this paper, we illustrate possible mechanisms both with optical coherence tomography (OCT) and histology. Design. We present two cases ...

Femten norske og tre svenske familier med klinisk diagnostisert ’kongenitt myotoni (MC)’ er inkludert i studiet. Alle pasienter likesom deres førstegrads slektninger er undersøkt nøye klinisk og elektromyografisk (EMG). Systematisk undersøkelse av CLCN1 gen er da utført for å finne mutasjoner. Nye mutasjoner blir studert med uttrykks studie for å finne ut deres funksjonelle konsekvens på kanal ...

Background Cancer survivors are a diverse group with varying needs that are patient-, disease-, and/or treatmentspecific. Cancer survivors have reported supplementing conventional anti-cancer treatment with Traditional and Complementary Medicine (T&CM). Although female cancer survivors are reported to have more severe anticancer adverse effects, little is known about the association between ...

Abstract Background There is a need for a common way of documenting and planning pharmaceutical care within the electronic prescribing system used at Ayr hospital. Aims and objectives Conduct a contents analysis of care issues in a formal survey of the care plans in order to categorise the issues, and propose a starting point for an electronic care plan template. Methods Documentation ...

Background Pharmaceutical care as a health care service has already made its mark and been shown to make an important contribution to the health care system. However, there is still a demand from the NHS among others, that pharmacist to a greater extent must document their provision of pharmaceutical care. Tested out in this project, is the application of a Care Issue Categorisation System. ...