Now showing items 1955-1974 of 10152

    • Decompressive hemicraniectomy for space-occupying brain infarction: Nationwide population-based registry study 

      Anke, Pablo; Pedersen, Lars Kjelsberg; Mathiesen, Ellisiv Bøgeberg; Ingebrigtsen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-14)
      Objective: We analyzed data from the Norwegian Stroke Registry (NSR) to study access to and outcomes of decompressive hemicraniectomy for brain infarction in a nationwide routine clinical setting. We also discretionary assessed whether the outcomes were comparable with those achieved in randomized controlled trials (RCTs), and whether the use was in accordance with guidelines. Methods: The NSR ...
    • Decrease in use of manual vacuum aspiration in postabortion care in Malawi: A cross-sectional study from three public hospitals, 2008-2012 

      Odland, Maria Lisa; Rasmussen, Hanne; Jacobsen, Geir Wenberg; Kafulafula, UK; Chamanga, P; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-25)
    • The decreasing prevalence of nonrefractive visual impairment in older Europeans: a meta-analysis of published and unpublished data 

      Delcourt, Cécile; Le Goff, Mélanie; von Hanno, Therese; Mirshahi, Alireza; Khawaja, Anthony P.; Verhoeven, Virginie J.M.; Hogg, Ruth E.; Anastosopoulos, Eleftherios; Cachulo, Maria Luz; Höhn, René; Wolfram, Christian; Bron, Alain; Miotto, Stefania; Carrière, Isabelle; Colijn, Johanna M.; Buitendijk, Gabriëlle H.S.; Evans, Jennifer; Nitsch, Dorothea; Founti, Panayiota; Yip, Jennifer L.Y.; Pfeiffer, Norbert; Creuzot-Garcher, Catherine; Silva, Rufino; Piermarocchi, Stefano; Topouzis, Fotis; Bertelsen, Geir; Foster, Paul J.; Fletcher, Astrid; Klaver, Caroline C.W.; Korobelnik, Jean-François (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-13)
      <p><i>Topic</i>: To estimate the prevalence of nonrefractive visual impairment and blindness in European persons 55 years of age and older.</p> <p><i>Clinical Relevance</i>: Few visual impairment and blindness prevalence estimates are available for the European population. In addition, many of the data collected in European population-based studies currently are unpublished and have not been ...
    • Decreasing trends in number of depot medroxyprogesterone acetate starters in Norway - a cross-sectional study 

      Roksvaag, Ingvild; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-20)
      <i>Introduction - </i>In this study, we examined changes in depot medroxyprogesterone acetate (DMPA) prescriptions over a time‐period when new professions started prescribing, and when the method gained some negative media attention.<br><br> <i>Material and methods - </i>The Norwegian Prescription Database provided data on hormonal contraception from 2006 through 2012. We estimated the annual number ...
    • The "deep caries" challenge. Prevalence and management of deep carious lesions in Northern Norway. 

      Stangvaltaite, Lina (Doctoral thesis; Doktorgradsavhandling, 2015-10-22)
      The overall aim of this doctoral thesis was to increase the understanding and knowledge of the prevalence and management of deep carious lesions. The prevalence of dental caries in Norway was among the highest in the world in the middle of 20th century. Though it has significantly declined, there are indications that the prevalence of caries in Northern Norway is higher than in the rest of the ...
    • Deep Learning Denoising Improves and Homogenizes Patient [18F]FDG PET Image Quality in Digital PET/CT 

      Weyts, Kathleen; Quak, Elske; Licaj, Idlir; Ciappuccini, Renaud; Lasnon, Charline; Corroyer-Dulmont, Aurélien; Foucras, Gauthier; Bardet, Stéphane; Jaudet, Cyril (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-04)
      Given the constant pressure to increase patient throughput while respecting radiation protection, global body PET image quality (IQ) is not satisfactory in all patients. We first studied the association between IQ and other variables, in particular body habitus, on a digital PET/CT. Second, to improve and homogenize IQ, we evaluated a deep learning PET denoising solution (Subtle PET<sup>TM</sup>) ...
    • Deep learning-based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis 

      Røyset, Elin Synnøve; Pettersen, Henrik Sahlin; Xu, Weili; Larbi, Anis; Sandvik, Arne Kristian; Steigen, Sonja Eriksson; Catalan-Serra, Ignacio; Bakke, Ingunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-23)
      Colon mucosae of ulcerative colitis (UC) and Crohn's disease (CD) display differences in the number and distribution of immune cells that are difficult to assess by eye. Deep learning-based analysis on whole slide images (WSIs) allows extraction of complex quantitative data that can be used to uncover different inflammatory patterns. We aimed to explore the distribution of CD3 and γδ T cells in colon ...
    • Deep learning-derived cardiovascular age shares a genetic basis with other cardiac phenotypes 

      Libiseller-Egger, Julian; Phelan, Jody E.; Attia, Zachi I.; Benavente, Ernest Diez; Campino, Susana; Friedman, Paul A.; Lopez-Jimenez, Francisco; Leon, David A.; Clark, Taane G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-31)
      Artifcial intelligence (AI)-based approaches can now use electrocardiograms (ECGs) to provide expertlevel performance in detecting heart abnormalities and diagnosing disease. Additionally, patient age predicted from ECGs by AI models has shown great potential as a biomarker for cardiovascular age, where recent work has found its deviation from chronological age (“delta age”) to be associated ...
    • Default, time-pressured and incentivized deliberate reasoning 

      Abukar, Fozia Aweys (Mastergradsoppgave; Master thesis, 2021-05-14)
      The purpose of this study was to investigate the effect time-pressure and incentives have on deliberate reasoning. A person’s tendency to engage in and enjoy processes that require reasoning, i.e., their need for cognition, and their algorithmic ability are factors that may moderate performance in reasoning tasks when they are under time-pressure or given monetary reward. Identifying how to increase ...
    • Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD 

      Goode, Alice; Butler, Kevin; Long, Jed; Cavey, James; Scott, Daniel; Shaw, Barry; Sollenberger, Jill; Gell, Christopher; Johansen, Terje; Oldham, Neil J.; Searle, Mark S.; Layfield, Robert (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-12)
      Growing evidence implicates impairment of autophagy as a candidate pathogenic mechanism in the spectrum of neurodegenerative disorders which includes amyotrophic lateral sclerosis and frontotemporal lobar degeneration (ALS-FTLD). SQSTM1, which encodes the autophagy receptor SQSTM1/p62, is genetically associated with ALS-FTLD, although to date autophagy-relevant functional defects in disease-ass ...
    • Defining and Scoping Participatory Health Informatics - An eDelphi Study 

      Denecke, Kerstin; Rivera-Romero, Octavio; Petersen, Carolyn; Benham-Hutchins, Marge; Cabrer, Miguel; Davies, Shauna; Grainger, Rebecca; Hussein, Rada; Lopez Campos, Guillermo; Martin-Sanchez, Fernando J.; McKillop, Molle; Merolli, Mark; Miron-Shatz, Talya; Trigo, Jesús Daniel; Wright, Graham; Wynn, Rolf; Hullin, Carola; Gabarron, Elia (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-14)
      Background - Health care has evolved to support the involvement of individuals in decision making by, for example, using mobile apps and wearables that may help empower people to actively participate in their treatment and health monitoring. While the term “participatory health informatics” (PHI) has emerged in literature to describe these activities, along with the use of social media for health ...
    • Defining compulsive exercise in eating disorders: acknowledging the exercise paradox and exercise obsessions 

      Bratland-Sanda, Solfrid; Mathisen, Therese Fostervold; Sundgot-Borgen, Jorunn; Rosenvinge, Jan H (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-04)
      Recently Dittmer et al. (JED 6:1–9, 2018). suggested a transdiagnostic definition and a clinical assessment for compulsive exercise in adolescents and adults with eating disorders. In this letter to the editor, we extend the transdiagnostic bridge to the DSM-5-criteria for obsessive-compulsive disorders and hence raise the issue of exercise obsession without compulsive exercise actions. We argue ...
    • Definisjon av en lavrisikopopulasjon i fødselshjelpen : kan dette gjøre sammenligning mellom fødeinstitusjoner mer meningsfylt? 

      Nyegaard, Cecilie (Master thesis; Mastergradsoppgave, 2007)
      Det er ofte vanskelig å sammenlikne resultater fra norske fødeinstitusjoner fordi fødepopulasjonen kan være høyst forskjellig. Det kan derfor være ønskelig å definere en standard lavrisikopopulasjon som gjør at sammenligning mellom institusjoner blir mer meningsfylt. Med utgangspunkt i en studie fra Storbritannia ønsket vi å se om definisjon av en såkalt standardpopulasjon kan være relevant ...
    • Deformable liposomes for skin therapy with human epidermal growth factor: The effect of liposomal surface charge 

      Ternullo, Selenia; Basnet, Purusotam; Holsæter, Ann Mari; Flaten, Gøril Eide; de Weerd, Louis; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-07)
      The topical administration of exogenous human epidermal growth factor (hEGF) is a promising approach for improved chronic wound therapy. To develop therapeutically superior hEGF formulation, we prepared hEGF-containing neutral (NDLs), cationic (CDLs) and anionic (ADLs) deformable liposomes (DLs), respectively, since it is expected that the liposomal surface charge can affect both the liposomal ...
    • Degradation of arouser by endosomal microautophagy is essential for adaptation to starvation in Drosophila 

      Jacomin, Anne-Claire; Gohel, Raksha; Hussain, Zunoon; Varga, Agnes; Maruzs, Tamas; Eddison, Mark; Sica, Margaux; Jain, Ashish; Moffat, Kevin G.; Johansen, Terje; Jenny, Andreas; Juhasz, Gabor; Nezis, Ioannis (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-14)
      Hunger drives food-seeking behaviour and controls adaptation of organisms to nutrient availability and energy stores. Lipids constitute an essential source of energy in the cell that can be mobilised during fasting by autophagy. Selective degradation of proteins by autophagy is made possible essentially by the presence of LIR and KFERQ-like motifs. Using in silico screening of Drosophila ...
    • Dekontaminering av pattedyrslakt ved bruk av damp eller varmt vann. Uttalelse fra Faggruppe for hygiene og smittestoffer i Vitenskapskomiteen for mattrygghet 

      Nesbakken, Truls; Christensen, Hardy; Skjerve, Eystein; Nygård, Karin Maria; Yazdankhah, Siamak Pour; Lunestad, Bjørn Tore; Kapperud, Georg; Lassen, Jørgen Fr; Robertson, Lucy; Olsvik, Ørjan; Tranulis, Michael A.; Tryland, Morten; Rimstad, Espen (Research report; Forskningsrapport, 2010-04-15)
      Mattilsynet har gitt VKM i oppgave å foreta en risikovurdering når det gjelder ”dekontaminering av pattedyrslakt ved bruk av varmt vann eller damp”. Da det er en bestemtdekontamineringsteknologi Mattilsynet ønsker utredet, velger faggruppen å bruke den mer presise betegnelsen ”overflatepasteurisering av slakt” som er i tråd med uttrykk og definisjoner som forskere innenfor dette området har benyttet ...
    • Delay of Dental Care: An Exploratory Study of Procrastination, Dental Attendance, and Self-Reported Oral Health 

      Steinvik, Lene Marita; Svartdal, Frode; Johnsen, Jan-Are Kolset (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-20)
      Delay of dental care is a problem for dental public health. The present study explored the relationship between procrastination and dental attendance, focusing on delay in seeking dental care. This hypothetical relation was compared to other avoidance-related factors affecting dental attendance. In addition, an inquiry into the reasons for delaying dental care was conducted. Students (n = 164) ...
    • Delayed clearance of triglyceride-rich lipoproteins in young, healthy obese subjects 

      Larsen, Maria Arlén; Goll, Rasmus; Lekhal, Samira; Moen, Odd S.; Florholmen, Jon (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-15)
      Obesity is associated with the metabolic syndrome. The aims were, first, to study the postprandial triglyceride clearance in young, healthy obese subjects and, second, to investigate if fasting triglycerides can predict delayed postprandial triglyceride clearance. Eighteen apparently healthy, obese subjects with no clinical signs of metabolic disturbances participated. Controls were age‐ and ...
    • Delayed leukocytosis after hard strength and endurance exercise. Aspects of regulatory mechanisms 

      Risøy, Bjørn Audun; Lappegård, Knut T.; Raastad, Truls; Hallén, Jostein; Bæverfjord, Kjersti; Kravdal, Astrid; Siebke, Else Marie; Benestad, Haakon B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2003-12-11)
      Background: During infections, polymorphonuclear neutrophilic granulocytes (PMN) are mobilized from their bone marrow stores, travel with blood to the affected tissue, and kill invading microbes there. The signal(s) from the inflammatory site to the marrow are unknown, even though a number of humoral factors that can mobilize PMN, are well known. We have employed a standardized, non-infectious ...
    • Delayed sleep phase syndrome and melatonin treatment: A meta-analysis 

      Engebråten, Carina Femoen (Master thesis; Mastergradsoppgave, 2014-05-02)
      Delayed sleep phase syndrome er en søvnforstyrrelse som oppstår blant barn og unge voksne, som forårsaker vanskeligheter med å fungere normalt på dagtid når søvn-våken rytmen er forskjøvet. Diagnosen er vanlig, men det er allikevel ingen standardiserte rettningslinjer for behandling. Forskning de siste årene har funnet ut at hormonet melatonin påvirker søvn og endring av søvn-våken syklusen hos ...