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    • Dietary amino acids and risk of stroke subtypes: a prospective analysis of 356,000 participants in seven European countries 

      Tong, Tammy Y. N.; Clarke, Robert Michael; Schmidt, Julie A.; Huybrechts, Inge; Noor, Urwah; Forouhi, Nita G.; Imamura, Fumiaki; Travis, Ruth C.; Weiderpass Vainio, Elisabete; Aleksandrova, Krasimira; Dahm, Christina C.; van der Schouw, Yvonne T.; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Kaaks, Rudolf; Katzke, Verena; Schiborn, Catarina; Schulze, Matthias B.; Mayen-Chacon, Ana-Lucia; Masala, Giovanna; Sieri, Sabina; de Magistris, Maria Santucci; Tumino, Rosario; Sacerdote, Carlotta; Boer, Jolanda M. A.; Verschuren, W. M. Monique; Brustad, Magritt; Nøst, Therese Haugdahl; Crous-Bou, Marta; Petrova, Dafina; Amiano, Pilar; Huerta, José María; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Johansson, Kristina; Lindvall, Kristina; Aglago, Elom K.; Heath, Alicia K.; Butterworth, Adam S.; Danesh, John; Key, Timothy J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-07)
      Purpose - Previously reported associations of protein-rich foods with stroke subtypes have prompted interest in the assessment of individual amino acids. We examined the associations of dietary amino acids with risks of ischaemic and haemorrhagic stroke in the EPIC study.<p> <p>Methods - We analysed data from 356,142 participants from seven European countries. Dietary intakes of 19 individual ...

    • Dietary calanus oil recovers metabolic flexibility and rescues postischemic cardiac function in obese female mice 

      Jansen, Kirsten; Moreno, Sonia; Garcia-Roves, Pablo M; Larsen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-16)
      The aim of this study was to find out whether dietary supplementation with Calanus oil (a novel marine oil) or infusion of exenatide (an incretin mimetic) could counteract obesity-induced alterations in myocardial metabolism and improve postischemic recovery of left ventricular (LV) function. Female C57bl/6J mice received high-fat diet (HFD, 45% energy from fat) for 12 wk followed by 8-wk feeding ...

    • Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery 

      Brunvoll, Sonja Hjellegjerde; Thune, Inger; Bertheussen, Gro Falkener; Fjeldheim, Frøydis Nyborg; Flote, Vidar Gordon; Frydenberg, Hanne; Lundgren, Steinar; Skjerven, Helle; Lømo, Jon; Fagerland, Morten; McTiernan, Anne; Schlichting, Ellen; Hjartåker, Anette (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-19)
      The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ dietary changes during the 12 months post-surgery and from 12 months pre-surgery to 12 months post-surgery with repeated administration of a 7-d pre-coded food diary and an FFQ, respectively. ...

    • Dietary chlorpyrifos-methyl exposure impair transcription of immune-, detoxification- and redox signaling genes in leukocytes isolated from cod (Gadus morhua) 

      Holen, Elisabeth; Espe, Marit; Larsen, Anett Kristin; Olsvik, Pål Asgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-05)
      Inclusion of new environmental toxicants increase with the amount of plant ingredients substituting marine proteins and oils in feed for farmed Atlantic salmon (Salma salar). Agricultural pesticides like chlorpyrifos-methyl, present in commercial salmon feeds, may affect salmon immune and detoxification responses. Atlantic cod (Gadus morhua), surrounding the net pens, grazing on feces and uneaten ...

    • Dietary data in the Norwegian Women and Cancer Study : validation and analyses of health related aspects 

      Hjartåker, Anette (Doctoral thesis; Doktorgradsavhandling, 2000)
      The objectives of the present thesis were to design a semi-quantitative food frequency questionnaire for use in epidemiological research among Norwegian women, to validate certain components of the dietary data, to collect dietary data from a large nation-wide sample of women, and to analyse selected nutritional aspects related to health, both cross-sectionally and prospectively. The data are ...

    • Dietary fat intake and gestational weight gain in relation to estradiol and progesterone plasma levels during pregnancy : a longitudinal study in Swedish women 

      Weiderpass, Elisabete; Lof, Marie; Hilakivi-Clarke, Leena; Sandin, Sven S.; de Assis, Sonia; Yu, Wei (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-04-30)
      Background: Elevated pregnancy hormone levels, such as oestrogen and progesterone, may increase the risk of developing breast cancer both in mothers and offspring. However, the reasons for large inter-individual variations in estrogen and progesterone levels during pregnancy remain unknown. The objectives of this study were to investigate whether a) intakes of total dietary fat, types of fat ...

    • Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition 

      Yammine, S.G.; Huybrechts, I.; Biessy, C.; Dossus, L.; Panico, S.; Sánchez, M.J.; Benetou, V.; Turzanski-Fortner, R.; Katzke, V.; Idahl, A.; Skeie, Guri; Olsen, Karina Standahl; Tjønneland, A.; Halkjaer, J.; Colorado-Yohar, S.; Heath, A.K.; Sonestedt, E.; Sartor, H.; Schulze, M.B.; Palli, D.; Crous-Bou, M.; Dorronsoro, A.; Overvad, K.; Gurrea, A. Barricarte; Severi, G.; Vermeulen, R.C.H.; Sandanger, Torkjel M; Travis, R.C.; Key, T.; Amiano, P.; Van Guelpen, Guelpen; Johansson, Mattias; Sund, M.; Tumino, R.; Wareham, N.; Sacerdote, C.; Krogh, V.; Brennan, P.; Riboli, E.; Weiderpass, Elisabete; Gunter, M.J.; Chajès, V. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-16)
      Background - Diet may impact important risk factors for endometrial cancer such as obesity and inflammation. However, evidence on the role of specific dietary factors is limited. We investigated associations between dietary fatty acids and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).<p> <p>Methods - This analysis includes 1,886 incident ...

    • Dietary fatty acids, macronutrient substitutions, food sources and incidence of coronary heart disease: Findings from the EPIC-CVD case-cohort study across nine european countries 

      Steur, Marinka; Johnson, Laura; Sharp, Stephen J.; Imamura, Fumiaki; Sluijs, Ivonne; Key, Timothy J.; Wood, Angela M.; Chowdhury, Rajiv; Guevara, Marcela; Jakobsen, Marianne Uhre; Johansson, Ingegerd; Koulman, Albert; Overvad, Kim; Sánchez, Maria-José; van der Schouw, Yvonne T.; Trichopoulou, Antonia; Weiderpass, Elisabete; Wennberg, Maria; Zheng, Ju-Sheng; Boeing, Heiner; Boer, Jolanda M. A.; Boutron-Ruault, Marie-Christine; Ericson, Ulrika; Heath, Alicia K.; Huybrechts, Inge; Imaz, Liher; Kaaks, Rudolf; Krogh, Vittorio; Kühn, Tilman; Kyrø, Cecilie; Masala, Giovanna; Melander, Olle; Moreno-Iribas, Conchi; Panico, Salvatore; Quirós, José R.; Rodríguez-Barranco, Miguel; Sacerdote, Carlotta; Santiuste, Carmen; Skeie, Guri; Tjønneland, Anne; Tumino, Rosario; Monique Verschuren, Verschuren; Zamora-Ros, Raúl; Dahm, Christina C.; Perez-Cornago, Aurora; Schulze, Matthias B.; Tong, Tammy Y.N.; Riboli, Elio; Wareham, Nick; Danesh, John; Butterworth, Adam S.; Forouhi, Nita G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-07)
      BACKGROUND: There is controversy about associations between total dietary fatty acids, their classes (saturated fatty acids [SFAs], monounsaturated fatty acids, and polyunsaturated fatty acids), and risk of coronary heart disease (CHD). Specifically, the relevance of food sources of SFAs to CHD associations is uncertain.<p> METHODS AND RESULTS: We conducted a case-cohort study involving 10 529 ...

    • Dietary Fibre Intake and Risks of Cancers of the Colon and Rectum in the European Prospective Investigation into Cancer and Nutrition (EPIC) 

      Murphy, Neil; Norat, Teresa; Ferrari, Pietro; Jenab, Mazda; Bueno-de-Mesquita, H. Bas; Skeie, Guri; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Clavel-Chapelon, Françoise; Boutron-Ruault, Marie Christine; Racine, Antoine; Kaaks, Rudolf; Teucher, Birgit; Boeing, Heiner; Bergmann, Manuela M.; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Lagiou, Pagona; Palli, Domenico; Pala, Valeria; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Siersema, Peter D.; van Duijnhoven, Fränzel J.B.; Peeters, Petra H M; Hjartåker, Anette; Engeset, Dagrun; Gonzalez, Carlos A.; Sánchez, Maria-José; Dorronsoro, Miren; Navarro, Camen; Ardanaz, Eva; Quirós, José R.; Sonestedt, Emily; Ericson, Ulrika; Nilsson, Lena; Palmqvist, Richard; Khaw, Kay-Tee; Wareham, Nick; Key, Timothy J.; Crowe, Francesca L.; Fedirko, Veronika; Wark, Petra A.; Chuang, Shu-Chun; Riboli, Eilo (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Earlier analyses within the EPIC study showed that dietary fibre intake was inversely associated with colorectal cancer risk, but results from some large cohort studies do not support this finding. We explored whether the association remained after longer follow-up with a near threefold increase in colorectal cancer cases, and if the association varied by gender and tumour location. After a mean ...

    • Dietary flavonoid intake and colorectal cancer risk in the European prospective investigation into cancer and nutrition (EPIC) cohort 

      Zamora-Ros, Raul; Barupal, Dinesh Kumar; Rothwell, Joseph A.; Jenab, Mazda; Fedirko, Veronika; Romieu, Isabelle; Aleksandrova, Krasimira; Overvad, Kim; Kyrø, Cecilie; Tjønneland, Anne; Affret, Aurélie; His, Mathilde; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; Naska, Androniki; Kritikou, Maria; Saieva, Calogero; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Fasanelli, Francesca; Weiderpass, Elisabete; Skeie, Guri; Merino, Susana; Jakszyn, Paula; Sánchez, María-José; Dorronsoro, Miren; Navarro, Carmen; Ardanaz, Eva; Sonestedt, Emily; Ericson, Ulrika; Maria Nilsson, Lena; Bodén, Stina; Bueno-De-Mesquita, Hendrik Bastiaan; Peeters, Petra H.; Perez-Cornago, Aurora; Wareham, Nicholas J.; Khaw, Kay-Thee; Freisling, Heinz; Cross, Amanda J.; Riboli, Elio; Scalbert, Augustin (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-22)
      Flavonoids have been shown to inhibit colon cancer cell proliferation in vitro and protect against colorectal carcinogenesis in animal models. However, epidemiological evidence on the potential role of flavonoid intake in colorectal cancer (CRC) development remains sparse and inconsistent. We evaluated the association between dietary intakes of total flavonoids and their subclasses and risk of ...

    • Dietary folate intake and pancreatic cancer risk: Results from the European prospective investigation into cancer and nutrition 

      Park, Jin Young; Bueno-de-Mesquita, Hendrik Bastiaan; Ferrari, Pietro; Weiderpass, Elisabete; de Batlle, Jordi; Tjønneland, Anne; Kyrø, Cecilie; Rebours, Vinciane; Boutron-Ruault, Marie-Christine; Mancini, Francesca Romana; Katzke, Verena; Kühn, Tilman; Boeing, Heiner; Trichopoulou, Antonia; La Vecchia, Carlo; Kritikou, Maria; Masala, Giovanna; Pala, Valeria; Tumino, Rosario; Panico, Salvatore; Peeters, Petra H.; Skeie, Guri; Merino, Susana; Duell, Eric J.; Rodríguez-Barranco, Miguel; Dorronsoro, Miren; Chirlaque, Maria-Dolores; Ardanaz, Eva; Gylling, Björn; Schneede, Jørn; Ericson, Ulrika; Sternby, Hanna; Khaw, Kay-Tee; Bradbury, Kathryn E.; Huybrechts, Inge; Aune, Dagfinn; Vineis, Paolo; Slimani, Nadia (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-04)
      Pancreatic cancer (PC) has an exceptionally low survival rate and primary prevention strategies are limited. Folate plays an important role in one‐carbon metabolism and has been associated with the risk of several cancers, but not consistently with PC risk. We aimed to investigate the association between dietary folate intake and PC risk, using the standardised folate database across 10 European ...

    • Dietary intake and changes in relation to BMI SDS and metabolic measures in a childhood obesity intervention – Finnmark Activity School 

      Berglund, Thea (Master thesis; Mastergradsoppgave, 2021-05-16)
      Background: Overweight and obesity in childhood doubles the risk of becoming overweight as an adult, as well as it increases the risk of related comorbidities. Cardiovascular diseases are a consequence of obesity and the most common cause of death worldwide. Diet and physical activity are modifiable causes of overweight. Overweight and obesity should be prevented, but treatment must be optimized as ...

    • Dietary Intake of 91 Individual Polyphenols and 5-Year Body Weight Change in the EPIC-PANACEA Cohort 

      Gil-Lespinard, Mercedes; Castañeda, Jazmín; Almanza-Aguilera, Enrique; Gómez, Jesús Humberto; Tjønneland, Anne; Kyrø, Cecilie; Overvad, Kim; Katzke, Verena; Schulze, Matthias B.; Masala, Giovanna; Agnoli, Claudia; Santucci de Magistris, Maria; Tumino, Rosario; Sacerdote, Carlotta; Skeie, Guri; Lasheras, Cristina; Molina-Montes, Esther; Huerta, José María; Barricarte, Aurelio; Amiano, Pilar; Sonestedt, Emily; da Silva, Marisa Eleonor; Johansson, Ingegerd; Hultdin, Johan; May, Anne M.; Forouhi, Nita G.; Heath, Alicia K.; Freisling, Heinz; Weiderpass, Elisabete; Scalbert, Augustin; Zamora-Ros, Raul (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)
      Polyphenols are bioactive compounds from plants with antioxidant properties that may have a protective role against body weight gain, with adipose tissue and systemic oxidative stress as potential targets. We aimed to investigate the dietary intake of individual polyphenols and their association with 5-year body weight change in a sub-cohort of the European Prospective Investigation into Cancer and ...

    • Dietary intake of acrylamide and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort 

      Obon-Santacana, M; Kaaks, R; Slimani, N; Lujan-Barroso, L; Freisling, H; Ferrari, P; Dossus, L; Chabbert-Buffet, N; Baglietto, L; Fortner, RT; Boeing, H; Tjønneland, A; Olsen, A; Overvad, K; Menéndez, V; Molina-Montes, E; Larrañaga, N; Chirlaque, MD; Ardanaz, E; Khaw, KT; Wareham, N; Travis, RC; Lu, Y; Merritt, MA; Trichopoulou, A; Benetou, V; Trichopoulos, D; Saieva, C; Sieri, S; Tumino, R; Sacerdote, C; Galasso, R; Bueno-De-Mesquita, HB; Wirfält, E; Ericson, U; Idahl, A; Ohlson, N; Skeie, Guri; Gram, Inger Torhild; Weiderpass, Elisabete; Onland-Moret, NC; Riboli, E; Duell, EJ (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Dietary Intake of Advanced Glycation End Products (AGEs) and Mortality among Individuals with Colorectal Cancer 

      Mao, Ziling; Aglago, Elom K.; Zhao, Zhiwei; Schalkwijk, Casper C; Jiao, Li; Freisling, Heinz; Weiderpass, Elisabete; Hughes, David J.; Eriksen, Anne Kirstine; Tjønneland, Anne; Gianluca, Severi; Rothwell, Joseph A; Boutron-Ruault, Marie-Christine; Katzke, Verena; Kaaks, Rudolf; Birukov, Anna; Schulze, Matthias B; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Ricceri, Fulvio; Bueno-De-Mesquita, Bas; Vermeulen, Roel C.H.; Gram, Inger Torhild; Skeie, Guri; Sandanger, Torkjel M; Quiros, J Ramon; Crous-Bou, Marta; Sanchez, Maria-Jose; Amiano, Pilar; Chirlaque, Maria-Dolores; Barricarte Gurrea, Aurelio; Manjer, Jonas; Johansson, Ingegerd; Perez-Cornago, Aurora; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Advanced glycation end-products (AGEs) may promote oxidative stress and inflammation and have been linked to multiple chronic diseases, including cancer. However, the association of AGEs with mortality after colorectal cancer (CRC) diagnosis has not been previously investigated. Multivariable Cox proportional hazards models were used to calculate hazard ratios and corresponding 95% confidence ...

    • Dietary intake of advanced glycation endproducts (AGEs) and cancer risk across more than 20 anatomical sites: A multinational cohort study 

      Córdova, Reynalda; Mayén, Ana-Lucia; Knaze, Viktoria; Aglago, Elom Kouassivi; Schalkwijk, Casper; Wagner, Karl-Heinz; Overvad, Kim; Tjønneland, Anne; Kyrø, Cecilie; Katzke, Verena Andrea; Cornet, Charlotte Le; Schulze, Matthias Bernd; Birukov, Anna; Palli, Domenico; Grioni, Sara; Pasanisi, Fabrizio; Catalano, Alberto; Sandanger, Torkjel M; Gram, Inger Torhild; Skeie, Guri; Crous-Bou, Marta; Molina-Montes, Esther; Amiano, Pilar; Colorado-Yohar, Sandra Milena; Ardanaz, Eva; Drake, Isabel; Manjer, Jonas; Johansson, Ingegerd; Esberg, Anders; Perez-Cornago, Aurora; Weiderpass, Elisabete; Jenab, Mazda; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-04)

    • Dietary intake of advanced glycation endproducts and risk of hepatobiliary cancers: A multinational cohort study 

      Ana-Lucia, Mayén; Aglago, Elom K.; Knaze, Viktoria; Cordova, Reynalda; Schalkwijk, Casper G.; Wagner, Karl-Heinz; Aleksandrova, Krasimira; Fedirko, Veronika; Keski-Rahkonen, Pekka; Leitzmann, Michael F.; Katzke, Verena; Srour, Bernard; Schulze, Matthias B.; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Bueno-de-Mesquita, Bas; Brustad, Magritt; Agudo, Antonio; López, María Dolores Chirlaque; Amiano, Pilar; Ohlsson, Bodil; Ramne, Stina; Aune, Dagfinn; Weiderpass, Elisabete; Jenab, Mazda; Freisling, Heinz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-25)
      Advanced glycation endproducts (AGEs) may contribute to liver carcinogenesis because of their proinflammatory and prooxidative properties. Diet is a major source of AGEs, but there is sparse human evidence on the role of AGEs intake in liver cancer etiology. We examined the association between dietary AGEs and the risk of hepatobiliary cancers in the European Prospective Investigation into Cancer ...

    • Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population 

      Hedelin, Maria; Weiderpass, Elisabete; Löf, Marie; Olsson, Marita; Lewander, T; Nilsson, Björn; Hultman, Christina M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)

    • Dietary intake of marine n-3 polyunsaturated fatty acids and future risk of venous thromboembolism 

      Isaksen, Trond; Evensen, Line Holtet; Johnsen, Stein Harald; Jacobsen, Bjarne K.; Hindberg, Kristian; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-13)
      <p><i>Background</i>: Studies on the association between long‐chained n‐3 polyunsaturated fatty acids (n‐3 PUFAs) and risk of venous thromboembolism (VTE) are conflicting, potentially due to challenges related to assessment of n‐3 PUFA intake and changes in diet during follow‐up.</p> <p><i>Objectives</i>: To investigate whether dietary intake of marine n‐3 PUFAs was associated with risk of incident ...

    • Dietary intake of marine polyunsaturated fatty acids and incidence, recurrence and mortality related to venous thromboembolism 

      Isaksen, Trond (Doctoral thesis; Doktorgradsavhandling, 2020-11-27)
      Venøs tromboembolisme (VTE) er en fellesbetegnelse på dyp venetrombose (DVT) og lungeemboli (LE). VTE er en vanlig og alvorlig karsykdom hvor forekomsten har vært svakt økende de siste årene. Marine omega-3 fettsyrer (n-3 PUFAs) har flere gunstige effekter på hemostasemekanismen. Målet med denne doktorgradsavhandlingen var å undersøke sammenhengen mellom inntak av marine n-3 PUFAs i kosten og risikoen ...