Age-related changes in the liver sinusoidal endothelium, particularly the reduction in fenestrations, contribute to insulin resistance in old age. Metformin impacts on the aging process and improves insulin resistance. Therefore, the effects of metformin on the liver sinusoidal endothelium were studied. Metformin increased fenestrations in liver sinusoidal endothelial cells isolated from both young ...

Background - The safety and efficacy of oral anticoagulation for prevention of major adverse cardiovascular events in people with atrial fibrillation and spontaneous intracranial haemorrhage are uncertain. We planned to estimate the effects of starting versus avoiding oral anticoagulation in people with spontaneous intracranial haemorrhage and atrial fibrillation.<p> <p>Methods - In this prospective ...

An experimental investigation of the relationship between communicator dominance and persuasion is reported. In the study, persuasion was examined as a function of experimental treatments that differed only in the perceived dominance of stimulus embedded within a text. Perceived dominance of the stimulus is operationally defined as the degree to which the stimulus makes the recipient feel ...

Selective serotonin reuptake inhibitors (SSRIs) are increasingly prescribed as medication for various affective disorders during pregnancy. SSRIs cross the placenta and affect serotonergic neurotransmission in the fetus, but the neurobehavioral consequences for the offspring remain largely unclear. Recent research has linked perinatal SSRI exposure to alterations in both social and non-social ...

In this systematic review, I investigated the effect of psychological and psychosocial interventions for refugees. The objective of this master thesis was to look at the effects of psychological and psychosocial intervention on PTSD and/or depression for adult refugees in Europe who suffers from PTSD and/or depression.

<p><i>Background - </i>Birth weight is an important indicator for predicting newborn baby’s health. Particular toxic elements: lead (Pb), arsenic (As), mercury (Hg), cadmium (Cd) have ability to cross the transplacental barrier and effect the fetal growth and development. These toxic elements exposure during pregnancy have been associated with negative birth outcomes like low birth weight (LBW). ...

<p>Objective: Team handball is a physically demanding sport. Research has not kept up with the increasing number of women participating in exercise and sports. The menstrual cycle (MC) is complex and should be included when conducting sport and exercise research on female athletes. Therefore, the main aim of this study was to investigate the potential effects of three different phases of the menstrual ...

Objectives: From a developmental perspective, infancy is a critical stage of life. Early childhood interventions aim to support caretakers, but the effects of universal interventions for parents with infants are unknown. The objective is to determine the effects of universal parenting interventions offered to parents with infants 0–12 months on measures of child development and parent–child relationship. ...

Objective: Respiratory function is linked to sensory, affective, and cognitive processes and it is affected by environmental constraints such as cognitive demands. It is suggested that specific cognitive processes, such as working memory or executive functioning, may impact breathing. In turn, various lines of research have suggested a link between peak expiratory airflow (PEF) and cognitive function. ...