Det helsevitenskapelige fakultet: Nye registreringer
Viser treff 641-660 av 10982
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Cutaneous nerve biopsy in patients with symptoms of small fiber neuropathy: a retrospective study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-22)Objectives - We aimed to investigate to what extent small fiber tests were abnormal in an unselected retrospective patient material with symptoms suggesting that small fiber neuropathy (SFN) could be present, and to evaluate possible gender differences.<p> <p>Methods - Nerve conduction studies (NCS), skin biopsy for determination of intraepidermal nerve fiber density (IENFD) and quantitative ... -
Serum and salivary inflammatory biomarkers in juvenile idiopathic arthritis—an explorative cross-sectional study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-09)Background - Biomarkers may be useful in monitoring disease activity in juvenile idiopathic arthritis (JIA). With new treatment options and treatment goals in JIA, there is an urgent need for more sensitive and responsive biomarkers.<p> <p>Objective - We aimed to investigate the patterns of 92 inflammation-related biomarkers in serum and saliva in a group of Norwegian children and adolescents ... -
Prevention of obstetric anal sphincter injuries with perineal support and lateral episiotomy: A historical cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-05)Introduction - There are many risk factors for obstetric anal sphincter injury (OASIS) and the interaction between these risk factors is complex and understudied. The many observational studies that have shown a reduction of OASIS rates after implementation of perineal support have short follow-up time. We aimed to study the effect of integration of active perineal support and lateral episiotomy on ... -
Repeat expansions in AR, ATXN1, ATXN2 and HTT in Norwegian patients diagnosed with amyotrophic lateral sclerosis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-14)Genetic repeat expansions cause neuronal degeneration in amyotrophic lateral sclerosis as well as other neurodegenerative disorders such as spinocerebellar ataxia, Huntington’s disease and Kennedy’s disease. Repeat expansions in the same gene can cause multiple clinical phenotypes. We aimed to characterize repeat expansions in a Norwegian amyotrophic lateral sclerosis cohort. Norwegian amyotrophic ... -
Valg og erfaringer innvandrerkvinner gjør seg ved deltakelse på Mammografiprogrammet
(Master thesis; Mastergradsoppgave, 2022-08-21)<p>Bakgrunn: I både kvantiative og kvalitative studier om innvandrerkvinner og kreftscreening har fokuset vært på faktorer som svekker oppmøte og deltakelse. Brukerkunnskap i form av kunnskap om kvinners rasjonale, erfaringer og tilfredshet ved deltakelse på Mammografi- programmet har vært fokuset i mange studier. Derimot har et fåtall studier sett på innvandrerkvinner som faktisk møter opp på ... -
Utfordringer og suksessfaktorer ved rehabilitering av sykelig overvektige i spesialisthelsetjenesten i Nord-Norge: En observasjonsstudie som tar utgangspunkt i pasientenes og behandlernes erfaringer ved behandlingen av fedme
(Master thesis; Mastergradsoppgave, 2019-08-20)Bakgrunn: Fedme er økende globalt, også i Norge. Konservativ behandling i form av adferdsterapi kombinert med fysisk aktivitet og lavkalori diett er et alternativ som tilbys av spesialisthelsetjenesten for sykelig overvektige i Nord-Norge. Formål: Hovedformålet er å se på pasientenes, det tverrfaglige rehabiliteringsteamets og fastlegers erfaringer og meninger om behandlingen av fedme, med fokus ... -
Hypoparathyreoidisme etter total thyreoidektomi - har vi blitt bedre?
(Master thesis; Mastergradsoppgave, 2022-08-18)Denne studien har som formål å følge opp en studie fra 2017 hvor en fant høy insiders av PHP hos pasienter operert med total thyreoidektomi ved UNN, og undersøke om insidensen fremdeles er like høy. Et sentralt spørsmål er å identifisere eventuelle risikofaktorer, med mål om å senke komplikasjonsraten. Resultater og konklusjon: 108 pasienter ble registrert i Eurocrine-registeret med operasjonskode ... -
Forekomst av funksjonelle psykoser i den eldre befolkningen: Et systematisk litteraturstudium
(Master thesis; Mastergradsoppgave, 2022-08-17)Andelen eldre mennesker (>60 år) i befolkningen øker, det samme gjør levealderen. Fagfeltet geriatri er i vekst, men fortsatt mangler det mye forskning, særlig når det gjelder psykoselidelser blant eldre. En del forskning er gjort med tanke på de sekundære psykosene, derimot finnes det lite god forskning når det gjelder primære psykoselidelser blant eldre. Formålet med denne studien er å kartlegge ... -
Bruk av hormonell prevensjon og brukerkarakteristika hos kvinner 40-49 år
(Master thesis; Mastergradsoppgave, 2022-08-17)Bakgrunn: Formålet med oppgaven er å undersøke bruk av hormonell prevensjon og brukerkarakteristika hos kvinner i alderen 40-49 år med data fra den syvende Tromsøundersøkelsen. Materiale og metode: Studien er en deskriptiv analyse. Vi inkluderte kvinner i alderen 40-49 år som var seksuelt aktive det siste året, og ekskluderte kvinner som var seksuelt inaktive, gravide, prøvde å bli gravide, infertile ... -
Group dynamics in avalanche terrain. A qualitative study of backcountry skier’s experiences with group dynamics and their influence on decision-making in avalanche terrain
(Master thesis; Mastergradsoppgave, 2024-05-29)This study examines how the influence of group dynamics affects decision-making among experienced backcountry skiers in avalanche terrain. The study explores individual skiers' perspectives of group experiences in avalanche terrain and investigates how group dynamics have affected their decision-making. The study has a scientific-theoretical position of a critical qualitative orientation. This ... -
Isolation of trophoblast cells from first trimester placentas - Optimizing a protocol for future investigation of placenta and platelet alloimmunization
(Master thesis; Mastergradsoppgave, 2022-08-19)Background: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a pregnancy complication caused by an HPA-incompatibility between mother and fetus. In Caucasians, mainly maternal anti-HPA-1a antibodies cause FNAIT. It has been hypothesized that maternal anti-HPA-1a antibodies might affect not only the fetal platelets, but also the placenta, in alloimmunized pregnancies. However, the link between ... -
Diabetesretinopati i Tromsøundersøkelsen Prevalens, insidens og risikofaktorer
(Master thesis; Mastergradsoppgave, 2022-08-19)Sammendrag Bakgrunn: Diabetes retinopati (DR) er en av de viktigste årsakene til nedsatt syn og blindhet globalt. Denne studien undersøker prevalens, risikofaktorer og kumulativ insidens av øyesykdommen basert på data fra den sjette- og syvende Tromsøundersøkelsen. Materiale og metode: Tromsø øyestudie (TES) er en delstudie av den befolkningsbaserte Tromsøundersøkelsen. Basert på data fra Tromsø ... -
Preoperativ adenomlokalisering ved primær hyperparatyreoidisme - En retrospektiv registerstudie av opererte pasienter på UNN
(Master thesis; Mastergradsoppgave, 2022-08-18)Bildeundersøkelser har blitt standard preoperativ prosedyre ved behandling av primær hyperparatyreoidisme (pHPT), og ultralyd og scintigrafi er de to mest brukte bildediagnostiske verktøyene. Choline-PET har de siste ti årene fått økt aksept som preoperativ lokaliseringsteknikk ved behandling av pHPT. I 2019 startet Bryst- og endokrinkirurgisk seksjon på UNN å registrere sine operasjonsdata i det ... -
Environmental contaminants in Arctic human populations: Trends over 30 years
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-05-25)Introduction - Arctic Monitoring and Assessment Programme (AMAP) monitors persistent organic pollutant (POP) levels in the Arctic populations and assesses health effects related to exposure to them. Many internationally regulated POPs persist in humans and biota, while new Emerging Contaminants of Arctic Concern (ECAC), many of which are unregulated, present additional challenges. Biomonitoring ... -
Perceived Parenting Stress Is Related to Cardiac Flexibility in Mothers: Data from the NorBaby Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-05)Heart rate variability (HRV) is an indicator of autonomic nervous system activity, and high levels of stress and/or depressive symptoms may reduce HRV. Here, we assessed whether (a) parental stress affected HRV in mothers during the perinatal period and whether this is mediated by bonding and (b) whether antenatal maternal mental states, specifically repetitive negative thinking, depressive symptoms, ... -
Metaproteomics of Gut Fungi in Gnotobiotic Mice
(Journal article; Tidsskriftartikkel, 2024-06-29)Intestinal fungi are a fundamental component of the gut microbiome and play important roles in mammalian host biology. At the same time, the contribution of gut fungi to host health and disease remains understudied due to their low abundance. In that respect, gnotobiotic animals with defined microbial populations of reduced complexity represent a well-suited model system that highlights the effects ... -
Age and healthy lifestyle behavior’s disparities and similarities on knowledge of myocardial infarction symptoms and risk factors among public and outpatients in a resource-limited setting, cross-sectional study in greater Gaborone, Botswana
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-04)Objectives In this cross-sectional study from Botswana, we investigated knowledge of myocardial infarction (MI) symptoms and risk factors among the general public and outpatients with MI risk factors based on age and lifestyle behaviors, in addition to assessing associations with sociodemographic and MI risk factors.<p> <p>Method Open-ended questionnaires about 8 MI symptoms and 10 risk factors, ... -
Activity-Based Protein Profiling (ABPP) and functional validation of uncharacterized enzymes in bacterial pathogens Staphylococcus aureus and Klebsiella pneumoniae
(Doctoral thesis; Doktorgradsavhandling, 2024-08-30)<i>Staphylococcus aureus</i> and <i>Klebsiella pneumoniae</i> often reside in the human body as harmless commensal bacteria but can cause various infections once they breach the host's immune defenses. These pathogens are increasingly difficult to treat due to the emergence of antibiotic-resistant strains such as methicillin-resistant <i>S. aureus</i> (MRSA) and carbapenem-resistant <i>K. pneumoniae</i>. ... -
Integrating Pharmacists in Emergency Departments: Exploring Key Factors for Future Physician-Pharmacist Collaboration
(Doctoral thesis; Doktorgradsavhandling, 2024-08-30)Medication-related problems pose a significant burden to patients and healthcare services, especially during transitions of care, such as moving from home to the emergency department (ED). Based upon the knowledge that up to 80% of medication lists in hospitals contain discrepancies upon hospital admission and that approximately 20% of admissions are medication-related, the "Pharmacist in the Emergency ... -
The effect of hormonal contraception on skeletal muscle hypertrophy and strength over an 8-week training intervention in recreational female strength athletes
(Master thesis; Mastergradsoppgave, 2024-05-29)Background: There is limited research on how hormonal contraceptives (HC) may influence skeleton muscle hypertrophy and strength adaptations from resistance exercise training (RET), with no studies to date investigating long-acting reversible contraceptives (LARCs). Current research on HC shows mixed results regarding their impact on hypertrophy and strength. Furthermore, most research has been ...