Evaluation of a pharmacist-led cardiovascular risk clinic for patients with diabetes attending a hospital out-patient clinic
ForfatterMajid Alwan, Ahmed
Cardiovascular disease is strongly associated with diabetes; hypertension is prominent in diabetic patients. In 2003 a pharmacist-led cardiovascular risk reduction clinic was established to reduce cardiovascular risk in diabetic patients. The aim of this study was to evaluate the feasibility of outcome measures to inform a future prospective study to evaluate the pharmacist-led clinic and to measure the impact of the clinic on cardiovascular risk reduction. A spreadsheet was designed to be populated with patients’ information from patients attending the pharmacist-led clinic and the usual care. The process of data collection was performed retrospectively by case note review. Forty five patients were included in the intervention group (pharmacist's patients) and 42 in the control group (doctor's patients). There were significant differences in duration of diabetes (p=0.003), HbA1c (p=0.026) and number of comorbidities (p0.022) at baseline. The reduction in SBP was significant (p=0.0088) and the number of patients reaching target BP was significant (p =0.0036). Reduction in DBP, ACR and total cholesterol was insignificant. There was a significant difference in the number of antihypertensives started or increased (p<0.001) and a significant difference in the number of medication related problems actioned (p=0.0058). Reduction in BP and the proportion of patients reaching target BP change in pharmaceutical care plan drug therapy problems actioned can be used as outcome measures and primary end point in the future study. Reduction in ACR and the number of hospital admission might be used as feasible outcome measures if the intervention and the control group in the future study are similar and randomised correctly.
ForlagUniversitetet i Tromsø
University of Tromsø
Følgende lisensfil er knyttet til denne innførselen:
Viser innførsler relatert til tittel, forfatter og emneord.
Nikolaisen, Trygg Einar (Mastergradsoppgave; Master thesis, 2018-05-15)Introduction: Liposomes as drug delivery systems has been widely studied as a way to solubilize poorly soluble drugs, reduce side effects of chemotherapeutics and increase circulation time in vivo. Since the first descriptions of liposomes over 60 years ago, they have shown tendencies to shrink and swell when the external environment of the liposomes is altered. This phenomenon has been studied in ...
The Temporomandibular Joint in Juvenile Idiopathic Arthritis, focusing on Quality of Life, Oral Microbiome and Intervention Frid, Paula (Doctoral thesis; Doktorgradsavhandling, 2020-10-02)The temporomandibular joint (TMJ) is commonly involved in juvenile idiopathic arthritis (JIA), and may lead to impaired mouth opening, pain and facial growth disturbances. Asymptomatic TMJ arthritis may be diagnosed late in the disease course, thus management is challenging. The overall objectives of this thesis were to provide new knowledge on quality of life (QoL), the oral microbiome and interventions ...
Prognostic Impacts of Angiopoietins in NSCLC Tumor Cells and Stroma : VEGF-A Impact Is Strongly Associated with Ang-2 Andersen, Sigve; Dønnem, Tom; Al-Shibli, Khalid Ibrahim; Al-Saad, Samer; Stenvold, Helge; Busund, Lill-Tove; Bremnes, Roy M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Angiopoietins and their receptor Tie-2 are, in concert with VEGF-A, key mediators in angiogenesis. This study evaluates the prognostic impact of all known human angiopoietins (Ang-1, Ang-2 and Ang-4) and their receptor Tie-2, as well as their relation to the prognostic expression of VEGF-A. 335 unselected stage I-IIIA NSCLC-patients were included and tissue samples of respective tumor cells and ...