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dc.contributor.authorBergkvist, Charlotte
dc.contributor.authorAune, Marie
dc.contributor.authorNilsson, Ingrid
dc.contributor.authorSandanger, Torkjel Manning
dc.contributor.authorHamadani, Jena Derakhshani
dc.contributor.authorTofail, Fahmida
dc.contributor.authorOdland, Jon Øyvind
dc.contributor.authorKabir, Iqbal
dc.contributor.authorVahter, Marie
dc.date.accessioned2013-03-13T10:24:53Z
dc.date.available2013-03-13T10:24:53Z
dc.date.issued2012
dc.description.abstractIn low-income countries, the use of some organochlorine pesticides is still common in order to increase food production. Monitoring the chemical exposure is an important step in risk-reducing strategies. This is the first study to report concentrations of organochlorines in breast milk of women from Bangladesh where farming is the main income source. Organochlorines such as p,p′-DDT, o,p′-DDT, p,p′-DDE, p,p′-DDD (i.e., ∑DDT), HCB, α-, β- and γ-HCH, trans-chlordane, cis-chlordane, oxy-chlordane, trans-nonachlor, cis-nonachlor, mirex and polychlorinated biphenyls (CB 28, 52, 99, 101, 105, 114, 118, 123, 128, 138, 141, 149, 153, 156, 157, 163, 167, 170, 180, 183, 187, 189, 194) were analyzed in breast milk collected in 2002 from 72 first-time mothers (median age 20 years) living in the rural area Matlab, Bangladesh. While the concentrations of PCBs and many of the pesticides were low, the concentrations of p,p′-DDT and its metabolite p,p′-DDE were high (median 349 and 1645 ng g−1 lipid, respectively) in comparison to other countries. The median value of ∑DDT was 2123 ng g−1 lipid. The estimated daily exposure to p,p′-DDT, p,p′-DDE and ∑DDTs was 10, 30 and 42 μg kg−1 body weight, respectively, in 3 months old infants. The p,p′-DDE/p,p′-DDT ratio ranged from 1 to 23, where 58% of the mothers had a ratio below 5 indicating recent or ongoing DDT exposure. This study reports infant exposure and maternal body burden of organochlorines through breast milk. Although the findings give no reason to limit breast-feeding, it is essential to identify the main exposure sources and find means to decrease the exposure.en
dc.identifier.citationChemosphere 88(2012) nr. 7 s. 784-790en
dc.identifier.cristinIDFRIDAID 967103
dc.identifier.doihttp://dx.doi.org/10.1016/j.chemosphere.2012.03.083
dc.identifier.issn0045-6535
dc.identifier.urihttps://hdl.handle.net/10037/4977
dc.identifier.urnURN:NBN:no-uit_munin_4729
dc.language.isoengen
dc.publisherElsevieren
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en
dc.titleOccurrence and levels of organochlorine compounds in human breast milk in Bangladeshen
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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