• Betydelsen av teori- och metodutvecklingen inom historieskrivningen för undervisningen i ämnet teknikhistoria 

      Wråkberg, Urban (Journal article; Tidsskriftartikkel; Peer reviewed, 1990)
    • The TNF Receptors p55 and p75 Mediate Chemotaxis of PMN Induced by TNFα and a TNFα 36–62 Peptide 

      Espevik, T.; Rekdal, Ø.; Konopski, Z.; Svendsen, J. S.; Winberg, J.-O.; Østerud, B. (Journal article; Tidsskriftartikkel; Peer reviewed, 1994)
      The present study was performed to examine whether residues 36–62 of TNFα contain the chemotactic domain of TNFα, and whether the p55 and p75 TNF receptors are involved in TNFα induced chemotaxis. The chemotactic effect of TNFα on PMN was inhibited by the mAbs Hrt-7b and Utr-1, against the p55 and p75 TNF receptors, respectively. Both receptors may therefore be required for mediating the chemotactic ...
    • Salivary glands in Svalbard reindeer (Rangifer tarandus platyrhynchus) and in Norwegian reindeer (Rangifer tarandus tarandus). 

      Rædergård, V.B.; Mathiesen, S.D.; Vader, M.A.; Haga, Ø.E.; Norberg, H.J.; Sørmo, W.; Tyler, N.J.C. (Journal article; Peer reviewed; Tidsskriftartikkel, 1999)
    • Loss of deuterium in faecal solids and by sequestration in reindeer. Effect on doubly labelled water studies. 

      Gotaas, Geir; Milne, Eric; Tyler, Nicholas J.C.; Haggarty, Paul (Journal article; Peer reviewed; Tidsskriftartikkel, 2000)
    • Biological rhythms in Arctic vertebrates. 

      Van Oort, B.E.H.; Tyler, N.J.C.; Reierth, E.; Stokkan, K.-A. (Journal article; Peer reviewed; Tidsskriftartikkel, 2000)
    • Energy expenditure of free-living reindeer estimated by the doubly labelled water method. 

      Milne, Eric; Gotaas, Geir; Tyler, Nicholas J.C.; Haggarty, Paul (Journal article; Peer reviewed; Tidsskriftartikkel, 2000)
    • Liver sinusoidal endothelial cells represents an important blood clearance system in pigs 

      Elvevold, Kjetil H.; Nedredal, Geir I.; Olsen, Randi; Ytrebø, Lars M.; Smedsrød, Bård; Revhaug, Arthur (Journal article; Tidsskriftartikkel; Peer reviewed, 2003-01-03)
      Background: Numerous studies in rats and a few other mammalian species, including man, have shown that the sinusoidal cells constitute an important part of liver function. In the pig, however, which is frequently used in studies on liver transplantation and liver failure models, our knowledge about the function of hepatic sinusoidal cells is scarce. We have explored the scavenger function of pig ...
    • Scavenger properties of cultivated pig liver endothelial cells 

      Elvevold, Kjetil H.; Nedredal, Geir I.; Revhaug, Arthur; Smedsrød, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2004-08-12)
      Background: The liver sinusoidal endothelial cells (LSEC) and Kupffer cells constitute the most powerful scavenger system in the body. Various waste macromolecules, continuously released from tissues in large quantities as a consequence of normal catabolic processes are cleared by the LSEC. In spite of the fact that pig livers are used in a wide range of experimental settings, the scavenger ...
    • Site-specific reverse splicing of a HEG-containing group I intron in ribosomal RNA 

      Birgisdottir, Åsa Birna; Johansen, Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The myxomycete Didymium iridis (isolate Panama 2) contains a mobile group I intron named Dir.S956-1 after position 956 in the nuclear small subunit (SSU) rRNA gene. The intron is efficiently spread through homing by the intron-encoded homing endonuclease I-DirI. Homing endonuclease genes (HEGs) usually spread with their associated introns as a unit, but infrequently also spread independent ...
    • The value of population campaigns offering free-of-charge HIV-testing 

      Holtedahl, Knut A.; Bonono, Leonard; Salpou, Daniel (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
    • The recent transfer of a homing endonuclease gene 

      Haugen, Peik; Wikmark, Odd-Gunnar; Vader, Anna; Coucheron, Dag H.; Sjøttem, Eva; Johansen, Steinar D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The myxomycete Didymium iridis (isolate Panama 2) contains a mobile group I intron named Dir.S956-1 after position 956 in the nuclear small subunit (SSU) rRNA gene. The intron is efficiently spread through homing by the intron-encoded homing endonuclease I-DirI. Homing endonuclease genes (HEGs) usually spread with their associated introns as a unit, but infrequently also spread independent of ...
    • The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions 

      Bruun, Jack-Ansgar; Thomassen, Ernst I.s.; Kristiansen, Kurt; Tylden, Garth Daryl; Holm, Turid; Mikkola, Ingvild; Bjørkøy, Geir; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2005)
      The transcription factor Pax6 is essential for the development of the eyes and the central nervous system of vertebrates and invertebrates. Pax6 contains two DNA-binding domains; an N-terminal paired domain and a centrally located homeodomain. We have previously shown that the vertebrate paired-less isoform of Pax6 (Pax6ΔPD), and several other homeodomain proteins, interact with the full-length ...
    • Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C 

      Ingebretsen, Ole C.; Kuklin, Vladimir N.; Kirov, Mikhail Y.; Sovershaev, Mikhail; Andreasen, Thomas; Ytrehus, Kirsti; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005-03-04)
      Introduction: Studies in vitro reveal that endothelin-1 (ET-1) activates the α isoform of protein kinase C (PKC-α) in cultures of endothelial cells, thereby deranging cellular integrity. Sepsis and endotoxemia are associated with increased plasma concentrations of ET-1 that induce acute lung injury (ALI). We recently reported that non-selective ET-1 receptor blockade attenuates ALI in sheep by ...
    • Characterisation of parapoxviruses isolated from Norwegian semi-domesticated reindeer (Rangifer tarandus tarandus) 

      Klein, Jörn; Tryland, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2005-09-05)
      Background: Two outbreaks of the disease contagious ecthyma were reported in 1999 and 2000 in Norwegian semi-domesticated reindeer (Rangifer tarandus tarandus). Contagious ecthyma is an epidermal disease of sheep and goats worldwide, which is caused by the zoonotic parapoxvirus orf virus. Characterisation of clinical samples from the two outbreaks in semi-domesticated reindeer in Norway by ...
    • Tezosentan reduces the microvascular filtration coefficient in isolated lungs from rats subjected to cecum ligation and puncture 

      Kuklin, Vladimir N.; Sovershaev, Mikhail; Andreasen, Thomas; Skogen, Vegard; Ytrehus, Kirsti; Bjertnæs, Lars J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005-10-18)
      Introduction: We recently demonstrated that the non-selective endothelin-1 (ET-1) receptor blocker tezosentan antagonizes ovine acute lung injury (ALI) following infusion of endotoxin or ET-1 by reducing the enhanced lung microvascular pressure, although we could not exclude the possibility of a simultaneous decline in microvascular permeability. In the present study, our aim was to find out if ...
    • A third approach to gene prediction suggests thousands of additional human transcribed regions 

      El-Gewely, M. Raafat; Glusman, Gustavo; Qin, Shizhen; Siegel, Andrew F.; Roach, Jared C.; Hood, Leroy; Smit, Arian F.A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-03)
      The identification and characterization of the complete ensemble of genes is a main goal of deciphering the digital information stored in the human genome. Many algorithms for computational gene prediction have been described, ultimately derived from two basic concepts: (1) modeling gene structure and (2) recognizing sequence similarity. Successful hybrid methods combining these two concepts have ...
    • Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron 

      Wikmark, Odd-Gunnar; De Jonckheere, Johan F.; Einvik, Christer; Johansen, Steinar D. (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-05-02)
      Background Ribosomal DNA of several species of the free-living Naegleria amoeba harbors an optional group I intron within the nuclear small subunit ribosomal RNA gene. The intron (Nae.S516) has a complex organization of two ribozyme domains (NaGIR1 and NaGIR2) and a homing endonuclease gene (NaHEG). NaGIR2 is responsible for intron excision, exon ligation, and full-length intron RNA circularization, ...
    • Alpha-actinin-binding antibodies in relation to systemic lupus erythematosus and lupus nephritis 

      Becker-Merok, Andrea; Kalaaji, Manar; Haugbro, Kaia; Nikolaisen, Cathrin; Nilsen, Kirsten; Rekvig, Ole Petter; Nossent, Johannes C (Journal article; Tidsskriftartikkel; Peer reviewed, 2006-10-24)
      This study investigated the overall clinical impact of anti-α- actinin antibodies in patients with pre-selected autoimmune diseases and in a random group of anti-nuclear antibody (ANA)- positive individuals. The relation of anti-α-actinin antibodies with lupus nephritis and anti-double-stranded DNA (anti-dsDNA) antibodies represented a particular focus for the study. Using a cross-sectional ...
    • Researching complementary and alternative treatments : the gatekeepers are not at home 

      Fønnebø, Vinjar; Grimsgaard, sameline; Norheim, Arne Johan; Walach, Harald; Ritenbaugh, Cheryl; Launsø, Laila; MacPherson, Hugh; Lewith, George; Koithan, Mary; Falkenberg, Torkel; Boon, Heather; Aickin, Mikel (Journal article; Tidsskriftartikkel; Peer reviewed, 2007)
    • Intensity Dependent Confidence Intervals on Microarray Measurements of Differentially Expressed Genes : A Case Study of the Effect of MK5, FKRP and TAF4 on the Transcriptome 

      Jakobsen, Kirsti; Van, Belle Werner; Brox, Vigdis; Gerits, Nancy; Van Ghelue, Marijke; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2007)