• Aspects of experimental cooling and rewarming with special reference to accidental hypothermia 

      Filseth, Ole Magnus (Doctoral thesis; Doktorgradsavhandling, 2012-08-17)
      Methods and aims We performed open, randomized, placebo-controlled experimental studies in intact, anesthetized pigs with the following main aims: Paper 1 To describe in detail the hemodynamic function with emphasis on left ventricular contractility during surface cooling, steady state severe hypothermia at 25°C, surface rewarming and in the post-hypothermic period of 2 h. Paper 2 1) To ...
    • Aspects of health services in Sami areas 

      Gaski, Margrete (Doctoral thesis; Doktorgradsavhandling, 2012-04-26)
      Helsepolitikk for samer har bygd på antakelser om at språk- og kulturforskjeller mellom helsepersonell og pasienter fører til et underforbruk av helsetjenester og en dårligere helsetjeneste. Første studie i denne avhandlingen analyserer forbruket av sykehus, og avviser at det er et underforbruk av helsetjenester blant samer generelt, men finner at de eldste innbyggerne i samiske kommuner er noe ...
    • Aspects of Lung Cancer by Sex 

      Hansen, Merethe Selnes (Doctoral thesis; Doktorgradsavhandling, 2020-06-12)
      Lung cancer is the most common cancer in men and the third most frequent in women across the globe, and the leading cause of cancer death worldwide. The rising worldwide incidence of lung cancer among women has raised the possibility of a sex difference in the association between smoking and lung cancer. It has been estimated that approximately 90% of all lung cancer is related to smoking. The ...
    • Aspects of the primary assessment and management of anal incontinence 

      Dehli, Trond (Doctoral thesis; Doktorgradsavhandling, 2013-04-05)
      Avhandlingens tittel er ”Aspects of the primary assessment and management of anal incontinence - The introduction of a new treatment”. Disputas for graden Ph.D. finner sted 05.04.2013. Ufrivillig lekkasje av luft og avføring er en relativt vanlig og belastende tilstand, og kan gi redusert livskvalitet. Det er utviklet en ny metode for å behandle denne lidelsen, som består i å injisere et rom-oppfyllende ...
    • Aspects on Recanalisation Therapies for Acute Ischaemic Stroke. Long-term survival after thrombolytic treatment with alteplase, endovascular thrombectomy for acute ischaemic stroke and recanalisation therapies for wake-up stroke 

      Roaldsen, Melinda Berg (Doctoral thesis; Doktorgradsavhandling, 2022-01-21)
      Stroke is a leading cause of death and disability worldwide. Approximately 85% of strokes are ischaemic strokes caused by blockage of a brain artery. Recanalisation therapies with thrombolysis (injection of drugs that dissolve the blood clot) and thrombectomy (mechanical removal of the blood clot) have revolutionised acute ischaemic stroke treatment during the last 25 years. Thrombolysis within ...
    • Assessing new prognostic biomarkers in resected colon cancer patients 

      Selven, Hallgeir (Doctoral thesis; Doktorgradsavhandling, 2023-06-22)
      Colon cancer is a common malignancy. We retrospectively established a biobank including 452 patients operated for colon cancer stage I-III in Northern Norway in the period 1998-2007. Tissue microarrays (TMAs) containing tumor tissue from these patients were constructed, and subsequently biomarker expression assessed by digital pathology. By using in situ hybridization, we assessed the expression of ...
    • An Assessment of Factors Influencing Use of Respiratory Protective Equipment in the Norwegian Smelter Industry and the Effect of a Knowledge-based Intervention 

      Robertsen, Øystein (Doctoral thesis; Doktorgradsavhandling, 2019-05-21)
      Chronic obstructive pulmonary disease (COPD), asthma and other respiratory illness have been shown to be more prevalent in Norwegian smelter workers compared to the general population. There is evidence suggesting that the use of respiratory protective equipment (RPE) can be sub-optimal in occupations with respiratory exposure. This thesis investigated psychological factors thought to influence ...
    • Assessment of LDL and HDL Subfractions and Metrics of HDL Function in High-Risk Patients of Cardiovascular Disease: Evaluation of Four Different Interventions 

      Kjellmo, Christian Abendstein (Doctoral thesis; Doktorgradsavhandling, 2023-10-27)
      Our research focused on assessing lipoprotein subfractions using the Lipoprint LDL® and HDL® system and evaluating metrics associated with HDL function. We examined data from four intervention trials involving high-risk patients of atherosclerotic cardiovascular disease (ASCVD). The interventions included lifestyle changes followed by bariatric surgery for morbidly obese patients, statin and ezetimibe ...
    • Assignment of mental health diagnoses and severity : effectiveness and reliability of online standardized assessment instruments 

      Brøndbo, Per Håkan (Doctoral thesis; Doktorgradsavhandling, 2012-09-26)
      During the last decade, child psychiatry has been a focus of the Norwegian government's plan to improve mental health care. Psychiatric assessment of children and adolescents is more complex than that of adults, and rating scales and diagnostic instruments have become increasingly important tools in both research and clinical practice. This dissertation investigates standardized assessment instruments ...
    • Associations between Primary Health Care- and Hospital Utilization among Elderly People in Norway 

      Deraas, Trygve Sigvart (Doctoral thesis; Doktorgradsavhandling, 2013-12-11)
      Summary Background: Geographical variations in health-care utilization in many countries have been an area of debate. Health-care supply factors, population and/or environmental need factors might explain the so-called small-area variations (SAVs). Demographic forecasts indicated a significant increase in the elderly population over the next few decades, with a resulting increased need for ...
    • Associations of widespread pain sensitivity, comorbid chronic pain and psychological distress with Irritable Bowel Syndrome and abdominal pain 

      Stabell, Niklas (Doctoral thesis; Doktorgradsavhandling, 2014-09-25)
      This is the first report documenting widespread hyperalgesia among adolescent and adult individuals with symptoms of IBS in the general population. Results were found to be independent of sex, comorbid pain and psychological distress. Increased pain sensitivity may contribute in triggering and maintaining chronic pain, but prospective studies are needed to examine these possible causal relationships. The ...
    • The ATLET study: Can subjects with long-standing motor incomplete spinal cord injury learn to walk? A randomized clinical trial 

      Piira, Anu Mirjam (Doctoral thesis; Doktorgradsavhandling, 2020-05-19)
      Body-weight supported locomotor training (BWSLT) has been used to improve walking function in subjects with incomplete Spinal Cord Injuries (SCI), but randomized controlled trials (RCTs) among subjects with long-standing (>2 years) incomplete SCI and poor walking function are scarce. This research aims to describe the methodology and report the results from two parallel, but independent, single-blinded ...
    • Atrial fibrillation in The Tromsø Study 1994-2007. Risk factors, occurrence and gender differences. 

      Nyrnes, Audhild (Doctoral thesis; Doktorgradsavhandling, 2016-01-14)
      Summary Atrial fibrillation (AF) is a common cardiac arrhythmia, which increases morbidity and mortality and thereby imposes high health costs on society. The prevalence of AF has increased for several decades, and is expected to increase further, with the rising numbers of elderly people and survivors of heart diseases. Several risk factors for AF related to genetics and diseases have been ...
    • Atrial Fibrillation: A prospective population study of risk factors and complications. The Tromsø Study 

      Tiwari, Sweta (Doctoral thesis; Doktorgradsavhandling, 2018-04-26)
      Background: Atrial Fibrillation (AF) is the most common arrhythmia associated with increased mortality and morbidity. It increases the lifetime risk of stroke and heart failure and affects one’s quality of life and cognition. Objective: To investigate diastolic dysfunction as risk factor for AF and AF as a risk factor for stroke and cognitive decline. Methods: Participants from the Tromsø Study ...
    • Attachment problems and mental health issues among long-term unemployed youth who had dropped out of high school 

      Ramsdal, Gro Hilde (Doctoral thesis; Doktorgradsavhandling, 2018-10-01)
      <i>Objectives</i>: We wanted to explore how unemployed youth, between 18 and 25 years of age, who had dropped out of school and were registered at the Norwegian Labour and Welfare Administration (NLWA), would describe and explain critical aspects of their school dropout processes (Study 1). Second, we wanted to investigate critically present knowledge on the role of parent-child attachment in school ...
    • Attitudes to evidence-based interventions and routine outcome measures in mental health professionals 

      Rye, Marte (Doctoral thesis; Doktorgradsavhandling, 2019-06-20)
      The complicated relationship between clinical health science and clinical practice has widely been referred to as the “science-practice gap”. This is for instance visible in the discrepancy between the amount of resources spent to develop and apply evidence-based treatment programmes and interventions (EBI) and the extent to which these interventions are used in real-life mental health care service ...
    • Autism Spectrum Disorders: Complexities associated with sex-differences, screening and diagnosis 

      Øien, Roald Andreas (Doctoral thesis; Doktorgradsavhandling, 2018-06-28)
      The present doctoral thesis examines screening and sex differences in autism spectrum disorders (ASD), and how behavioral, developmental and temperamental features of males and females affect early identification of the disorder. The present doctoral thesis found marked sex differences across all three studies, and furthermore found evidence of difficulties at identifying all children with an ASD ...
    • Å få og å ta i bruk eit teknisk hjelpemiddel - ei gåtefull reise. Ei kvalitativ undersøking av heimebuande eldre sine erfaringar. 

      Gramstad, Astrid (Doctoral thesis; Doktorgradsavhandling, 2014-09-26)
      Formidling av tekniske hjelpemiddel er eit hyppig brukt verkty for å gjere eldre i stand til å bu heime så lenge som mogleg. Likevel veit ein lite om korleis eldre erfarer det å få og å ta i bruk tekniske hjelpemiddel. Kunnskap om erfaringane til brukarar av hjelpemiddel kan bidra til ei vidareutvikling av klientsentrerte og effektive helsetenester. Formålet med prosjektet var difor å undersøkje ...
    • “Å sette staven igjen” – tilhørighet til familie, sted, personer og natur. Å fremme et meningsfylt liv for personer med demenssykdom i sykehjem i Nord-Norge. 

      Drageset, Ingrid Marie Saga (Doctoral thesis; Doktorgradsavhandling, 2015-01-23)
      Spørsmålet ”Eldre mennesker med demenssykdom: Hva betyr tilhørighet i eget liv for en meningsfylt tilværelse i sykehjemmet?” ble undersøkt ved intervju og feltarbeid med personer med demenssykdom, pårørende, pleiere og sykepleieledere i sykehjem i Nord-Norge. Et livsløpsperspektiv ble lagt til grunn. Dataene fra intervjuene ble analysert ved narrativ- og innholdsanalyse. Å få demenssykdom, og ...