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norskDoktorgradsavhandlinger (Helsefak): Nye registreringer
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Analysis of the Vibrionaceae pan-genome
(Doctoral thesis; Doktorgradsavhandling, 2013-06-21)In the presented work the bacterial family Vibrionaceae was used as a model to investigate bacterial diversity on a gene level and to analyze the underlying concepts of bacterial niche adaptation and evolution. For this, the genomes of a diverse dataset of 64 Vibrionaceae isolates from various environments and temperature zones were analyzed using existing as well as newly developed bioinformatics ... -
Retinopathy with and without diabetes: Risk factors and visual impairment.
(Doctoral thesis; Doktorgradsavhandling, 2013-03-22)Diabetic retinopathy is a well-known complication of diabetes and a major cause of visual impairment and blindness in developed countries. We explored visual impairment and diabetic retinopathy among participants with diabetes in the Tromsø Eye Study. The prevalence of visual impairment (corrected Snellen visual acuity < 20/40) was 4.1% in the better-seeing eye. We found no legally blind participants. ... -
Using the Internet to Manage Atopic Eczema
(Doctoral thesis; Doktorgradsavhandling, 2013-06-21) -
An assessment of decision-making by surgeons in management of colorectal cancer. International controversies and national practice.
(Doctoral thesis; Doktorgradsavhandling, 2013-05-10) -
Age-related macular degeneration: Prevalence and risk factors - a cross-sectional study : The Tromsø Study 2007/2008
(Doctoral thesis; Doktorgradsavhandling, 2013-05-30)Age-related macular degeneration (AMD) is an important cause of visual impairment and blindness worldwide. The number of people affected by the disease is expected to rise due to increasing longevity. Development of adequate eye care for these patients should be based on knowledge about the prevalence of AMD. Further, preventive measures are the best strategy for any disease. The aims of this ... -
Vitamin D, Depression and Headache - Results from the Tromsø Study and an intervention study with vitamin D
(Doctoral thesis; Doktorgradsavhandling, 2013-04-19)Vitamin D is well known for the effect in bone metabolism and calcium regulation. In the past decade increasing evidence that vitamin D might be important in other areas has emerged. Especially glucose metabolism, cardiovascular disease and infectious diseases have been investigated. In addition, several population studies have shown that an association between vitamin D and depression might be of ... -
Co-constructing standards in nursing
(Doctoral thesis; Doktorgradsavhandling, 2013-04-05)Avhandlingen presenterer en kvalitativ studie av innføring og bruk av standarder i sykepleie og bygger på empiriske studier fra ulike sykehusmiljø. Standardisering er ofte ansett som en viktig forutsetning for å oppnå sømløs integrasjon ved bruk av informasjons – og kommunikasjonsteknologi (IKT) i helsesektoren. Terminologier og retningslinjer blir ofte utviklet av internasjonale organisasjoner som ... -
Mucosal cytokine profiles as biomarkers in inflammatory bowel disease -Translating molecular biology into clinical medicine
(Doctoral thesis; Doktorgradsavhandling, 2013-01-11)Patogenesen ved inflammatorisk tarmsykdom (IBD) er fortsatt ikke fullstendig klarlagt. Mye forskning har blitt gjort de siste tjue årene for å kartlegge immunresponsen ved ulcerøs kolitt og Crohns sykdom. Man antar at et samspill mellom genetiske faktorer, miljøfaktorer og bakterier ligger bak utviklingen av sykdommen. Kartleggingen av immunresponsen i tarmen har vært grunnlaget for utviklingen av ... -
Family members' experiences of decision-making processes in the context of withholding or withdrawing treatment in the ICU. A qualitative interview study
(Doctoral thesis; Doktorgradsavhandling, 2013-01-24)This thesis is based on the decision-making process involved in treatment termination in intensive care. ICU patients often have impaired consciousness and may therefore lack capacity to consent. In such cases, the health care personnel have the decision-making authority, but where a serious intervention for the patient is involved, information should if possible be obtained from the patient’s ... -
Reducing infarct size by ischemic preconditioning versus insulin treatment in the heart : same outcome - similar mechanisms?
(Doctoral thesis; Doktorgradsavhandling, 2008-10-31)Doktoravhandlingen omhandler de gunstige effektene av å gi insulin når man åpner opp årene etter et hjerteinfarkt. Dette blir sammenliknet med beskyttelsen som ischemisk prekondisjonering (IPC) av hjertet gir. IPC er en metode hvor man stenger av blodtilførselen til hjertet i korte perioder fulgt av reperfusjon før en lengre ischemisk periode. Dette har vist seg å gi meget god beskyttelse mot det ... -
Respiratory symptoms, lung function, and occupational exposure among seafood industry workers. A study among employees at Norwegian salmon factories and Russian North-West trawl fleet (Arkhangelsk)
(Doctoral thesis; Doktorgradsavhandling, 2013-01-24) -
The coagulase negative staphylococci; molecular studies on Staphylococcus haemolyticus and novel treatment of staphylococcal biofilms in vitro and in vivo
(Doctoral thesis; Doktorgradsavhandling, 2013-01-25)The coagulase negative staphylococci (CoNS) were earlier regarded as innocuous inhabitants of the human normal skin flora, but are now emerging as opportunistic pathogens. In addition to their biofilm producing ability CoNS are frequently multi-resistant, and a high prevalence of methicillin resistant CoNS is found. Staphylococcus haemolyticus is an emerging cause of nosocomial infections, primarily ... -
Physical activity, mortality and breast cancer risk
(Doctoral thesis; Doktorgradsavhandling, 2013-03-21)4. Avhandlingen tar for seg effekten av fysisk aktivitet i forhold til total dødelighet, hjerte-kar og kreft dødelighet og risiko for brystkreft, samt validerer selv-rapportert fysisk aktivitet i Kvinner – og Kreft studien. Vi sammenlignet en fysisk aktivitetsskala fra 1 til 10, der deltagerne ble bedt om å krysse av fysisk aktivitetsnivå, med en sensor som målte puls og bevegelse over 4 døgn. ... -
Differentiated birth care for low-risk women Medical and economic perspectives
(Doctoral thesis; Doktorgradsavhandling, 2013-03-08) -
Prevalence, risk factors for and clinical impact of persistent hyperCKemia in a general population. The Tromsø Study
(Doctoral thesis; Doktorgradsavhandling, 2014-02-21) -
Staphylococcus epidermidis - virulence factors and innate immune response
(Doctoral thesis; Doktorgradsavhandling, 2012-04-26)S. epidermidis rank first among the causative agent of nosocomial infections, and accounts for more than 50% of the late-onset sepsis episodes in neonates. S. epidermidis often cause infections in immune-compromised patients Biofilm formation is the most important virulence factor of S. epidermidis. Its relevance has risen the past decades with the increased use of indwelling medical devices such ... -
Aspects of the primary assessment and management of anal incontinence
(Doctoral thesis; Doktorgradsavhandling, 2013-04-05)Avhandlingens tittel er ”Aspects of the primary assessment and management of anal incontinence - The introduction of a new treatment”. Disputas for graden Ph.D. finner sted 05.04.2013. Ufrivillig lekkasje av luft og avføring er en relativt vanlig og belastende tilstand, og kan gi redusert livskvalitet. Det er utviklet en ny metode for å behandle denne lidelsen, som består i å injisere et rom-oppfyllende ... -
The terminal phase of liver regeneration -differential gene expression, tissue remodelling and growth arrest of regenerating porcine liver
(Doctoral thesis; Doktorgradsavhandling, 2013-03-15)Etter et større vevstap vil leveren vokse ut igjen helt til den har gjenopprettet sitt opprinnelige volum og funksjon. Hos de fleste pattedyr slutter den å vokse når den veier omtrent 2,5% av den totale kroppsvekten. Det er forsket mye på hva som får leveren til å begynne å vokse, men når den er stor nok vet man lite om hva som får den til å “slå av” veksten. Vi ønsket å undersøke hvilke faktorer ... -
A study of fish consumption and cardiometabolic risk factors among the circumpolar population of the rural Nenets Autonomous Area in comparison with the urban population of Arkhangelsk County
(Doctoral thesis; Doktorgradsavhandling, 2012-12-14)Russia is a country with a high level of cardiovascular diseases (CVD) death. The nation has experienced several economic crises after the dissolution of the Soviet Union in 1991. While CVD-related deaths have decreased in Japan, North America and Western Europe during recent decades, CVD deaths in Russia have increased. Fish consumption is believed to have cardio-protective effects. Fish consumption ... -
Road traffic crashes in Arkhangelsk, Russia in 2005-2010
(Doctoral thesis; Doktorgradsavhandling, 2013-01-11)The research project “Road traffic crashes in Arkhangelsk, Russia in 2005-2010” is the basis for my PhD dissertation. It addresses traffic safety – a major public health concern in Russia. The dissertation describes recent trends and determinants of traffic safety in Arkhangelsk and will contribute a part of the evidence basis for planning local road safety measures in future. The Department of ...
