Objective: To evaluate the drug release, cytocompatibility with periodontal ligament cells (PDLCs), and therapeutic efficacy of GelMA hydrogel loaded with resolvin D1 (RvD1) in treating rat periodontal inflammation and alveolar bone damage. <p> <p>Methods: An RvD1 complexed with GelMA was prepared, and its release kinetics and compatibility with PDLCs were assessed. Rats with induced periodontitis ...

This article will present the data collection from the Norwegian scientists' research project on board Le Commandant Charcots North Pole expedition in AugustSeptember 2023, with a scope within Global Navigation Satellite Systems (GNSS), Low Earth Orbit (LEO) Communication Satellites and Ice Buoys. Operational testing in the artic environment is of particular interest, due to its high latitude, ...

Artikkelen handler om medvirkning for unge over 18 år som mottar hjelp fra barnevernet. Forskningsspørsmålet er: Hvilken betydning har medvirkningsprosesser i barnevernets oppfølging av unge over 18 år? Studien har et kvalitativt design, og en fenomenologisk og hermeneutisk tilnærming er valgt. Datamaterialet består av intervjuer med 30 ungdommer i alderen 17–25 år og er utforsket ved refleksiv ...

Recent advances in artificial intelligence (AI) have laid the foundation for developing a sophisticated collision avoidance system for use in maritime autonomous surface ships, potentially enhancing maritime safety and decreasing the navigator’s workload. Understanding the reasoning behind an AI system is inherently difficult. To help the human operator understand what the AI system is doing ...

Arctic sea-ice diatoms fuel polar marine food webs as they emerge from winter darkness into spring. Through their photosynthetic activity they manufacture the nutrients and energy that underpin secondary production. Sea-ice diatom abundance and biomolecular composition vary in space and time. With climate change causing short-term extremes and long-term shifts in environmental conditions, understanding ...

Nitroxides are stable organic radicals with exceptionally long lifetimes, which render them uniquely suitable as observable probes or polarising agents for spectroscopic investigation of biomolecular structure and dynamics. Radical-based probes for biological applications are ideally characterized by both robustness towards reductive degradation and beneficial electron spin relaxation parameters. ...

Context: Parker Solar Probe (PSP) counts dust impacts in the near-solar region, but modeling effort is needed to understand the dust population’s properties.<p> <p>Aims: We aim to constrain the dust cloud’s properties based on the flux observed by PSP.<p> <p>Methods: We developed a forward model for the bound dust detection rates using the formalism of 6D phase space distribution of the dust. ...

Objectives - Considering that the remission rate for major depressive disorder (MDD) in elderly patients is below 50%, there is a compelling requirement for an enhanced comprehension of the underlying mechanisms. Chronic low-grade inflammation has been posited as one potential contributor to treatment-resistant MDD in the elderly. Accordingly, the objective of our study was to explore the longitudinal ...

The WHO research agenda for antimicrobial resistance (AMR) in human health has identified 40 research priorities to be addressed by the year 2030. These priorities focus on bacterial and fungal pathogens of crucial importance in addressing AMR, including drug-resistant pathogens causing tuberculosis. These research priorities encompass the entire people-centred journey, covering prevention, diagnosis, ...

Background. Substance use may be associated with the onset of psychotic symptoms, necessitating treatment for individuals with comorbid mental health and substance use disorders (MHD/SUD). COVID-19 significantly impacted individuals with MHD/SUD, reducing access to appropriate care and treatment. Changes in drug availability and prices during the pandemic may have influenced drug consumption. ...