Atherogenesis is associated with elevated plasma levels of oxidized low-density lipoproteins (oxLDL). In vivo, oxLDL causes liver endothelial swelling, and disrupts liver sinusoidal endothelial cell (LSECs) fenestrations. We mapped the nanoscale kinetics of these changes in vitro in isolated rat LSECs challenged with oxLDL and monitored viability with endocytosis and cytotoxicity assays. OxLDL ...

During the Last Glacial Period (LGP), Greenland experienced approximately 30 abrupt warming phases, known as Dansgaard–Oeschger (D–O) events, followed by cooling back to baseline glacial conditions. Studies of mean climate change across warming transitions reveal indistinguishable phase offsets between shifts in temperature, dust, sea salt, accumulation, and moisture source, thus preventing a ...

This thesis explores the role of social capital in enhancing resilience within small communities in Northern Norway, focusing on the municipalities of Bardu and Karlsøy. Employing a mixed-methods approach with a qualitative emphasis, the study examines how bonding, bridging, and linking social capital contribute to community resilience during different phases of crises: preparation, response, and ...

The need for more skilled human resources and higher operational costs in conventional shipping will create the need for autonomous shipping. To make autonomous shipping a reality, the shipping industry will require building supportive infrastructure and facilities to ensure the safe operations of future autonomous vessels. To provide necessary support functions in autonomous vessel operations is ...

Current convolutional neural networks (CNNs) are not designed for large scientific images with rich multi-scale features, such as in satellite and microscopy domain. A new phase of development of CNNs especially designed for large images is awaited. However, application-independent high-quality and challenging datasets needed for such development are still missing. We present the ‘UltraMNIST ...

Accelerated Arctic warming and wetting has global impacts, as the region’s glaciers and ice caps respond to variations in temperature and precipitation, impacting global sea-level change. But as the observations needed to calibrate models are scarce, predictions cannot confirm if increases in snowfall can help offset melt. Here, we analyze two 14,000-year-long glacier-fed lake sediment records ...

The domain of online learning has experienced multifaceted expansion owing to its prevalence in real-life applications. Nonetheless, this progression operates under the assumption that the input feature space of the streaming data remains constant. In this survey paper, we address the topic of online learning in the context of haphazard inputs, explicitly foregoing such an assumption. We discuss, ...

Glacial groundwater is a conduit for geologic methane release in areas of glacier retreat on Svalbard, representing a large, climate-sensitive source of the greenhouse gas. Methane emissions from glacial melt rivers are known to occur in other regions of the Arctic, but such emissions have not yet been considered on Svalbard. Over the summer of 2021, we monitored methane concentrations in the ...

Textural, mineralogical and mineral compositional observations in a suite of Neoproterozoic aillikite and calcite kimberlite dykes from southern West Greenland point to consistent variations in melt major element compositions amongst these silica-undersaturated magma types. The aillikites have notably higher bulk SiO₂/CO₂, H₂O/CO₂ and K₂O compared ...

Increased temperature and high pressure are applied to β-lactoglobulin fibrils in the autoclave, resulting in the acquisition of a composite material comprised of partially disassembled amyloid fibrils and carbon dots. Confirmation of the preservation of the β-sheet motif attributed to amyloids in the hydrothermally treated fibrils is obtained through wide-angle X-ray scattering and ThT assay. Z-scan ...