Blar i forfatter Artikler, rapporter og annet (medisinsk biologi) "Øyjord, Tove Ragnhild"

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    • The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma 

      Nunes-Xavier, Caroline Elisabeth; Emaldi, Maite; Mingo, Janire; Øyjord, Tove Ragnhild; Mælandsmo, Gunhild Mari; Fodstad, Øystein; Errarte, Peio; Larrinaga, Gorka; Llarena, Roberto; López, José I.; Pulido, Rafael (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-05)
      Renal cancer cells constitute a paradigm of tumor cells with a glycolytic reprogramming which drives metabolic alterations favouring cell survival and transformation. We studied the expression and activity of pyruvate dehydrogenase kinases (PDK1-4), key enzymes of the energy metabolism, in renal cancer cells. We analysed the expression, subcellular distribution and clinicopathological correlations ...

    • p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance 

      Flem-Karlsen, Karine; Tekle, Christina; Øyjord, Tove Ragnhild; Flørenes, Vivi Ann; Mælandsmo, Gunhild Mari; Fodstad, Øystein; Nunes-Xavier, Caroline Elisabeth (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-09)
      Immunoregulatory protein B7-H3 is involved in the oncogenic and metastatic potential of cancer cells, as well as in drug resistance. Resistance to conventional chemotherapy is an important aspect of melanoma treatment, and a better understanding of how B7-H3 enhances drug resistance may lead to the development of more effective therapies. We investigated the <i>in vitro</i> and <i>in vivo</i> ...