Blar i forfatter Artikler, rapporter og annet (medisinsk biologi) "Efe, Gizem"

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    • MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy 

      Owyong, Mark; Chou, Jonathan; van den Bijgaart, Renske; Kong, Niwen; Efe, Gizem; Maynard, Carrie; Talmi-Frank, Dalit; Solomonov, Inna; Koopman, Charlotte; Hadler-Olsen, Elin Synnøve; Headley, Mark; Lin, Charlene; Wang, Chih-Yang; Sagi, Irit; Werb, Zena; Plaks, Vicki (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-14)
      Metastasis, the main cause of cancer-related death, has traditionally been viewed as a late-occurring process during cancer progression. Using the MMTV-PyMT luminal B breast cancer model, we demonstrate that the lung metastatic niche is established early during tumorigenesis. We found that matrix metalloproteinase 9 (MMP9) is an important component of the metastatic niche early in tumorigenesis and ...