• Evaluation of Merkel Cell Polyomavirus DNA in Tissue Samples from italian Patients With Diagnosis of MCC 

      Prezioso, Carla; Carletti, Raffaella; Obregon, Francisco; Piacentini, Francesca; Maricone, Anna Maria; Soda, Giuseppe; Moens, Ugo; Di Gioia, Cira; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-05)
      Because the incidence of Merkel cell carcinoma (MCC) has increased significantly during the last 10 years and it is recognized that Merkel cell polyomavirus (MCPyV) and ultraviolet (UV) radiation represent two different etiological inputs sharing clinical, histopathological, and prognostic similar features, although with different prognosis, this study investigated the detection of MCPyV in skin and ...
    • Structural Analysis of Merkel Cell Polyomavirus (MCPyV) Viral Capsid Protein (VP1) in HIV-1 Infected Individuals 

      Prezioso, Carla; Bianchi, Martina; Obregon, Francisco; Ciotti, Marco; Sarmati, Loredana; Andreoni, Massimo; Palamara, Anna Teresa; Pascarella, Stefano; Moens, Ugo; Pietropaolo, Valeria (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-27)
      Merkel cell polyomavirus (MCPyV) viral protein 1 (VP1) is the capsid protein that mediates virus attachment to host cell receptors and is the major immune target. Given the limited data on MCPyV VP1 mutations, the VP1 genetic variability was examined in 100 plasma and 100 urine samples from 100 HIV+ individuals. Sequencing of VP1 DNA in 17 urine and 17 plasma specimens, simultaneously MCPyV DNA ...