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    • CRISPR/Cas9—Advancing Orthopoxvirus Genome Editing for Vaccine and Vector Development 

      Okoli, Arinze Stanley; Okeke, malachy ifeanyi; Tryland, Morten; Moens, Ugo (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-22)
      : The clustered regularly interspaced short palindromic repeat (CRISPR)/associated protein 9 (Cas9) technology is revolutionizing genome editing approaches. Its high efficiency, specificity, versatility, flexibility, simplicity and low cost have made the CRISPR/Cas9 system preferable to other guided site-specific nuclease-based systems such as TALENs (Transcription Activator-like Effector ...