Blar i forfatter Artikler, rapporter og annet (medisinsk biologi) "Raghavan, Manoj"

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    • Crosstalk between AML and stromal cells triggers acetate secretion through the metabolic rewiring of stromal cells 

      Vilaplana-Lopera, Nuria; Cuminetti, Vincent; Almaghrabi, Ruba; Papatzikas, Grigorios; Rout, Ashok Kumar; Jeeves, Mark; González, Elena; Alyahyawi, Yara; Cunningham, Alan; Erdem, Ayşegül; Schnütgen, Frank; Raghavan, Manoj; Potluri, Sandeep; Cazier, Jean-Baptiste; Schuringa, Jan Jacob; Reed, Michelle AC; Arranz, Lorena; Günther, Ulrich L; Garcia, Paloma (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-02)
      Acute myeloid leukaemia (AML) cells interact and modulate components of their surrounding microenvironment into their own benefit. Stromal cells have been shown to support AML survival and progression through various mechanisms. Nonetheless, whether AML cells could establish beneficial metabolic interactions with stromal cells is underexplored. By using a combination of human AML cell lines and AML ...