Blar i forfatter Artikler, rapporter og annet (medisinsk biologi) "Zahoor, Muhammad"

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    • A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression 

      Ghannoum, Salim; Fantini, Damiano; Zahoor, Muhammad; Reiterer, Veronika; Phuyal, Santosh; Leoncio Netto, Waldir; Sørensen, Øystein; Iyer, Arvind; Sengupta, Debarka; Prasmickaite, Lina; Mælandsmo, Gunhild Mari; Kohn Luque, Alvaro; Farhan, Hesso (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-17)
      Our understanding of how speed and persistence of cell migration affects the growth rate and size of tumors remains incomplete. To address this, we developed a mathematical model wherein cells migrate in two-dimensional space, divide, die or intravasate into the vasculature. Exploring a wide range of speed and persistence combinations, we find that tumor growth positively correlates with increasing ...