Browsing Artikler, rapporter og annet (medisinsk biologi) by Author "Zykova, Svetlana"
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Hepatic disposal of advanced glycation end products during maturation and aging
Svistounov, Dmitri; Oteiza, Ana; Zykova, Svetlana; Sørensen, Karen Kristine; McCourt, Peter Anthony; McLachlan, Andrew J; Mccuskey, Robert Scott; Smedsrød, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)Aging is characterized by progressive loss of metabolic and biochemical functions and accumulation of metabolic by-products, including advanced glycation end products (AGEs), which are observed in several pathological conditions. A number of waste macromolecules, including AGEs are taken up from the circulation by endocytosis mainly into liver sinusoidal endothelial cells (LSECs) and Kupffer cells ... -
Low adiponectin is associated with diastolic dysfunction in women: A cross-sectional study from the Tromsø Study
Norvik, Jon Viljar; Schirmer, Henrik; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eggen, Anne Elise; Eriksen, Bjørn Odvar; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-14)Background: Heart failure with preserved ejection fraction is closely associated with diastolic dysfunction and related to obesity and female sex. We investigated whether adiponectin, an adipocyte-secreted protein hormone with cardioprotective effects, was associated with indices of diastolic dysfunction, and whether the association was sex dependent. <br>Methods: We conducted a cross-sectional ... -
Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study
Norvik, Jon Viljar; Storhaug, Hilde-Merete; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eriksen, Bjørn Odvar; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-10)Background: Elevated uric acid (UA) is associated with the presence of the metabolic syndrome (MetS). In a prospective cohort study, we assessed whether baseline and longitudinal change in UA were risk factors for development of MetS and its individual components. <br> Methods: We included 3087 women and 2996 men who had UA measured in the population based Tromsø Study 1994–95. The participants ... -
Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis
Zykova, Svetlana; Tveita, Anders Aune; Rekvik, Ole Petter (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)