Now showing items 1-4 of 4

    • Hepatic disposal of advanced glycation end products during maturation and aging 

      Svistounov, Dmitri; Oteiza, Ana; Zykova, Svetlana; Sørensen, Karen Kristine; McCourt, Peter Anthony; McLachlan, Andrew J; Mccuskey, Robert Scott; Smedsrød, Bård (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Aging is characterized by progressive loss of metabolic and biochemical functions and accumulation of metabolic by-products, including advanced glycation end products (AGEs), which are observed in several pathological conditions. A number of waste macromolecules, including AGEs are taken up from the circulation by endocytosis mainly into liver sinusoidal endothelial cells (LSECs) and Kupffer cells ...
    • Low adiponectin is associated with diastolic dysfunction in women: A cross-sectional study from the Tromsø Study 

      Norvik, Jon Viljar; Schirmer, Henrik; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eggen, Anne Elise; Eriksen, Bjørn Odvar; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-14)
      Background: Heart failure with preserved ejection fraction is closely associated with diastolic dysfunction and related to obesity and female sex. We investigated whether adiponectin, an adipocyte-secreted protein hormone with cardioprotective effects, was associated with indices of diastolic dysfunction, and whether the association was sex dependent. <br>Methods: We conducted a cross-sectional ...
    • Overweight modifies the longitudinal association between uric acid and some components of the metabolic syndrome: The Tromsø Study 

      Norvik, Jon Viljar; Storhaug, Hilde-Merete; Ytrehus, Kirsti; Jenssen, Trond Geir; Zykova, Svetlana; Eriksen, Bjørn Odvar; Solbu, Marit Dahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-10)
      Background: Elevated uric acid (UA) is associated with the presence of the metabolic syndrome (MetS). In a prospective cohort study, we assessed whether baseline and longitudinal change in UA were risk factors for development of MetS and its individual components. <br> Methods: We included 3087 women and 2996 men who had UA measured in the population based Tromsø Study 1994–95. The participants ...
    • Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis 

      Zykova, Svetlana; Tveita, Anders Aune; Rekvik, Ole Petter (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)