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dc.contributor.authorCouto, Elisabeth
dc.contributor.authorSandin, Sven
dc.contributor.authorLöf, Marie
dc.contributor.authorUrsin, Giske
dc.contributor.authorAdami, Hans-Olof
dc.contributor.authorWeiderpass, Elisabete
dc.date.accessioned2014-03-20T15:06:59Z
dc.date.available2014-03-20T15:06:59Z
dc.date.issued2013
dc.description.abstractBackground: A Mediterranean diet has a recognized beneficial effect on health and longevity, with a protective influence on several cancers. However, its association with breast cancer risk remains unclear. Objective: We aimed to investigate whether adherence to a Mediterranean dietary pattern influences breast cancer risk. Design: The Swedish Women’s Lifestyle and Health cohort study includes 49,258 women aged 30 to 49 years at recruitment in 1991–1992. Consumption of foods and beverages was measured at enrollment using a food frequency questionnaire. A Mediterranean diet score was constructed based on the consumption of alcohol, vegetables, fruits, legumes, cereals, fish, the ratio of unsaturated to saturated fat, and dairy and meat products. Relative risks (RR) for breast cancer and specific tumor characteristics (invasiveness, histological type, estrogen/progesterone receptor status, malignancy grade and stage) associated with this score were estimated using Cox regression controlling for potential confounders. Results: 1,278 incident breast cancers were diagnosed. Adherence to a Mediterranean dietary pattern was not statistically significantly associated with reduced risk of breast cancer overall, or with specific breast tumor characteristics. A RR (95% confidence interval) for breast cancer associated with a two-point increment in the Mediterranean diet score was 1.08 (1.00– 1.15) in all women, and 1.10 (1.01–1.21) and 1.02 (0.91–1.15) in premenopausal and postmenopausal women, respectively. When alcohol was excluded from the Mediterranean diet score, results became not statistically significant. Conclusions: Adherence to a Mediterranean dietary pattern did not decrease breast cancer risk in this cohort of relatively young women.en
dc.identifier.citationPLoS ONE (2013), vol. 8(2): e55374.en
dc.identifier.issn1932-6203
dc.identifier.otherFRIDAID 1027930
dc.identifier.otherhttp://dx.doi.org/10.1371/journal.pone.0055374
dc.identifier.urihttp://hdl.handle.net/10037/6013
dc.identifier.urnURN:NBN:no-uit_munin_5701
dc.language.isoengen
dc.publisherPublic Library of Science (PLoS)en
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Oncology: 762en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762en
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en
dc.titleMediterranean Dietary Pattern and Risk of Breast Canceren
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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