<p><i>Objectives - </i>The purpose of the study is to explore the prevalence and predictors of not engaged in education, employment or training (NEET) status in a multicultural young adult population in Northern Norway. <p><i>Design and setting - </i>The longitudinal design link a selfreported survey (2003–2005) with an objective registry linkage follow-up 8–10 years later. <p><i>Participants - ...

To study the flow of objects (tracers) in opaque flow processes, the PEPT (positron emission particle tracking) technique is utilized. The PEPT technique is based on the same principle of PET (positron emission tomography) which detects the characteristic back-to-back gamma pairs caused by positron-electron annihilation. The annihilation takes place within a few millimeters around the tracers labeled ...

<i>Background</i> - Many cases of acute lymphoblastic leukemia (ALL) carry visible acquired chromosomal changes of pathogenetic, diagnostic, and prognostic importance. Nevertheless, from one-fourth to half of newly diagnosed ALL patients have no visible chromosomal changes detectable by G-banding analysis at diagnosis. The introduction of powerful molecular methodologies has shown that many ...

<p>Introduction - LncRNAs have become a growing field of research. They are involved in diverse biological processes including expression regulation, and chromatin modification. Many lncRNAs have been characterized as involved in the occurrence and development of various human diseases, including cancer. A growing body of evidence implies a role for lncRNAs in UC by modulating the intestinal barrier, ...

Polyomaviruses are a family of small non-enveloped DNA viruses that encode oncogenes and have been associated, to greater or lesser extent, with human disease and cancer. Currently, twelve polyomaviruses are known to circulate within the human population. To further examine the diversity of human polyomaviruses, we have utilized a combinatorial approach comprised of initial degenerate primer-based ...

Two classical multivariate statistical problems, testing of multivariate normality and the <i>k</i>-sample problem, are explored by a novel analysis on several resolutions simultaneously. The presented methods do not invert any estimated covariance matrix. Thereby, the methods work in the High Dimension Low Sample Size situation, i.e. when <i>n</i> ≤ <i>p</i>. The output, a significance map, is ...

Aims The aim of this study was to establish age-specific and sex-specific cut-off values for N-terminal pro-brain natriuretic peptide (NT-proBNP) and high-sensitivity troponin T (hs-troponin T) in healthy subjects and assess cardiac biomarkers as screening tools for subclinical heart failure (HF) in a general population.<p> <p>Methods and results Altogether, 1936 participants were randomly selected ...

Denne rapporten er andre del av et oppdrag fra Sosial- og helsedirektoratet og RHF - fagdirektørene med fokus på virkestoffet trastuzumab ved adjuvant behandling av brystkreft. Adjuvant behandling gis i tillegg til hovedbehandlingen (for eksempel kirurgi) for å påvirke eventuelt gjenværende kreftceller hos pasienten. Denne delen av oppdraget vurderer de helseøkonomiske konsekvensene av adjuvant ...

I en ny studie, utført i flere europeiske land, er det undersøkt om legemiddelet Sulodexide kan forebygge at man får en ny blodpropp etter å først ha fått én. Etter at man har fått en blodpropp vil man få behandling med blodfortynnende medisin. For noen pasienter er dessverre risikoen for indre blødninger for stor med denne behandlingen, og behandlingen blir derfor avsluttet etter 3-12 måneder. Det ...