Now showing items 1-4 of 4

    • Effects of Vitamin D binding protein phenotypes and Vitamin D supplementation on serum total 25(OH)D and directly measured free 25(OH)D 

      Sollid, Stina Therese; Strand Hutchinson, Moira; Berg, Vivian; Fuskevåg, Ole-Martin; Figenschau, Yngve Anton; Thorsby, Per Medbøe; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-05)
      Objective:<br>To determine the relationship between serum total 25-hydroxyvitamin D (25(OH)D), directly measured free 25(OH)D and calculated free 25(OH)D with regard to vitamin D-binding protein (DBP) phenotypes, sex, BMI, age and season, and their interrelationship to vitamin D supplementation.<br>Design, patients and interventions:<br>A randomized controlled trial with 20 000 IU of vitamin D3 per ...
    • Estimated GFR is biased by non-traditional cardiovascular risk factors 

      Melsom, Toralf; Fuskevåg, Ole-Martin; Mathisen, Ulla Dorte; Strand, Harald; Schei, Jørgen; Jenssen, Trond Geir; Solbu, Marit Dahl; Eriksen, Bjørn Odvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-23)
      Background: Estimated glomerular filtration rate (eGFR) based on either cystatin C or creatinine perform similarly in estimating measured GFR, but associate differently with cardiovascular disease (CVD) and mortality. This could be due to confounding by non-GFRrelated traits associated with cystatin C and creatinine levels. We investigated non-GFRrelated associations between eGFR and two types ...
    • The impact of partial hepatectomy on oxidative state in the liver remnant - An in vivo swine model 

      Florholmen-Kjær, Åse; Goll, Rasmus; Fuskevåg, Ole-Martin; Nygård, Ingvild; Paulssen, Ruth H; Revhaug, Arthur; Mortensen, Kim Erlend (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-24)
      Background Previous studies on oxidative state after partial hepatectomy (PHx) report conflicting data on levels of glutathione (GSH) and are mainly presented in rodent models by methodology less sensitive than the present technologies. The current swine model presents GSH levels and the following genetic response post-PHx, utilizing an analytical platform more sensitive and precise than earlier ...
    • Urinary Markers of Oxidative Stress Are Associated With Albuminuria But Not GFR Decline 

      Schei, Jørgen; Fuskevåg, Ole-Martin; Stefansson, Vidar Tor Nyborg; Solbu, Marit Dahl; Jenssen, Trond Geir; Eriksen, Bjørn Odvar; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-07)
      <p><i>Introduction</i>: Markers of oxidative stress increase with age and are prevalent with chronic kidney disease. However, the role of oxidative stress markers as predictors for kidney function decline in the general population is unclear.</p> <p><i>Methods</i>: We investigated whether a baseline urinary excretion of oxidative DNA damage (8-oxo-7,8-dihydro-2′-deoxyguanosine [8-oxodG]) and ...