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dc.contributor.authorGrønli, Ole Kristian
dc.contributor.authorKvamme, Jan-Magnus
dc.contributor.authorJorde, Rolf
dc.contributor.authorWynn, Rolf
dc.date.accessioned2014-12-15T07:37:34Z
dc.date.available2014-12-15T07:37:34Z
dc.date.issued2014-05-08
dc.description.abstractBackground:Previous studies have found an association between psychiatric disorders and vitamin D deficiency, but most studies have focused on depression. This study aimed to establish the prevalence of vitamin D deficiency in elderly patients with a wider range of psychiatric diagnoses. Method: The study included elderly patients (>64 years) referred to a psychiatric hospital in Northern Norway and a control group from a population survey in the same area. An assessment of psychiatric and cognitive symptoms and diagnoses was conducted using the Montgomery and Aasberg Depression Rating Scale, the Cornell Scale for Depression in Dementia, the Mini Mental State Examination, the Clockdrawing Test, and the Mini International Neuropsychiatric Interview (MINI+), as well as clinical interviews and a review of medical records. The patients’ mean level of 25-hydroxyvitamin D (25(OH)D) and the prevalence of vitamin D deficiency were compared with those of a control group, and a comparison of vitamin D deficiency across different diagnostic groups was also made. Vitamin D deficiency was defined as 25(OH)D <50 nmol/L (<20 ng/ml). Results: The mean levels of 25(OH)D in the patient group (n = 95) and the control group (n = 104) were 40.5 nmol/L and 65.9 nmol/L (p < 0.001), respectively. A high prevalence of vitamin D deficiency was found in the patient group compared with the control group (71.6% and 20.0%, respectively; p < 0.001). After adjusting for age, gender, season, body mass index, and smoking, vitamin D deficiency was still associated with patient status (OR: 12.95, CI (95%): 6.03-27.83, p < 0.001). No significant differences in the prevalence of vitamin D deficiency were found between patients with different categories of psychiatric diagnoses, such as depression, bipolar disorders, psychosis, and dementia. Conclusion: Vitamin D deficiency is very common among psychogeriatric patients, independent of diagnostic category. Even though the role of vitamin D in psychiatric disorders is still not clear, we suggest screening for vitamin D deficiency in this patient group due to the importance of vitamin D for overall health.en
dc.descriptionThis article is part of Ole Kristian Grønli's doctoral thesis which is available in Munin at <a href=http://hdl.handle.net/10037/6930>http://hdl.handle.net/10037/6930</a>en
dc.identifier.citationBMC Psychiatry 2014, 14:134en
dc.identifier.cristinIDFRIDAID 1130890
dc.identifier.doiDOI: 10.1186/1471-244X-14-134
dc.identifier.issn1471-244X
dc.identifier.urihttps://hdl.handle.net/10037/6934
dc.identifier.urnURN:NBN:no-uit_munin_6535
dc.language.isoengen
dc.publisherBioMed Centralen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Gasteroenterologi: 773en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Psykiatri, barnepsykiatri: 757en
dc.titleVitamin D deficiency is common in psychogeriatric patients, independent of diagnosisen
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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