With an aging patient population and increasing complexity in patient disease trajectories, physicians are often met with complex patient histories from which clinical decisions must be made. Due to the increasing rate of adverse events and hospitals facing financial penalties for readmission, there has never been a greater need to enforce evidence-led medical decision-making using available ...

Melanoma is the deadliest form of skin cancer, and early detection is crucial for patient survival. Computer systems can assist in melanoma detection, but are not widespread in clinical practice. In 2016, an open challenge in classification of dermoscopic images of skin lesions was announced. A training set of 900 images with corresponding class labels and semi-automatic/manual segmentation masks ...

Black carbon (BC) and other light-absorbing particles deposited on snow and ice are known to perturb the surface radiative balance. There are few published observations of the concentration of these particles in the snow in Scandinavia and the European Arctic. We measured BC concentrations in snow samples collected in this region from 2007 to 2009, and we present the results here. The data set ...

This paper studies regional climate variability for the time period 1900–2013 using parsimonious stochastic models. Instrumental data records on 5° × 5°, 2° × 2°, and equal-area grids are examined. A long-range dependent (LRD) stochastic process is used as a simplified description of the multitude of response times in the climate system. Fitting a linear trend to the global mean surface temperature ...

The climate system approaches a tipping point if the prevailing climate state loses stability, making a transition to a different state possible. A result from the theory of randomly driven dynamical systems is that the reduced stability in the vicinity of a tipping point is accompanied by increasing fluctuation levels and longer correlation times (critical slowing down) and can in principle serve ...

In this article it is discussed how temperature variability on centennial timescales and longer can be described in a simplistic way. By analysing the scaling in late Holocene temperature reconstructions and longer temperature records from Greenland and Antarctic ice cores, we find that the choice of model depends heavily on the data material and timescale one chooses to emphasize. Ignoring data ...

In order to have a scaling description of the climate system that is not inherently non-stationary, the rapid shifts between stadials and interstadials during the last glaciation (the Dansgaard-Oeschger events) cannot be included in the scaling law. The same is true for the shifts between the glacial and interglacial states in the Quaternary climate. When these events are omitted from a scaling ...

Background: Previous studies have relied on international spirometry criteria to diagnose COPD in patients with lung cancer without considering the effect lung cancer might have on spirometric results. The aim of this study was to examine the prevalence of COPD and emphysema at the time of primary lung cancer diagnosis and to examine factors associated with survival. Materials and methods: Medical ...

We give a generalization of Kung’s theorem on critical exponents of linear codes over a finite field, in terms of sums of extended weight polynomials of linear codes. For all i=k+1,…,ni=k+1,…,n, we give an upper bound on the smallest integer m such that there exist m codewords whose union of supports has cardinality at least i.