Blar i forfatter "Wilsgaard, Tom"

Viser treff 21-40 av 190

    • Blood pressure and age-related GFR decline in the general population 

      Eriksen, Bjørn Odvar; Stefansson, Vidar Tor Nyborg; Jenssen, Trond Geir; Mathisen, Ulla Dorte; Schei, Jørgen; Solbu, Marit Dahl; Wilsgaard, Tom; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-28)
      Background: <br> Hypertension is one of the most important causes of end-stage renal disease, but it is unclear whether elevated blood pressure (BP) also accelerates the gradual decline in the glomerular filtration rate (GFR) seen in the general population with increasing age. The reason may be that most studies have considered only baseline BP and not the effects of changes in BP, antihypertensive ...

    • Blood pressure target achievement and antihypertensive medication use in women and men after first-ever myocardial infarction: the Tromsø Study 1994-2016 

      Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Løchen, Maja-Lisa; Mathiesen, Ellisiv B.; Nilsen, Amalie; Njølstad, Inger; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-03)
      Background: <br> Recurrent cardiovascular events after myocardial infarction (MI) are frequent, and gender differences in blood pressure treatment have been reported. Despite increased focus on secondary prevention, recent reports indicate that treatment targets are not achieved. There is a need for gender-specific analyses of post-MI blood pressure treatment target achievement and ...

    • Blood pressure, cardiorespiratory fitness and body mass : results from the Tromsø activity study 

      Wilsgaard, Tom; Furberg, Anne-Sofie (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)

    • Body mass index and mortality in elderly men and women: the Tromso and HUNT studies 

      Kvamme, Jan-Magnus; Holmen, Jostein; Wilsgaard, Tom; Florholmen, Jon; Midthjell, Kristian; Jacobsen, Bjarne Koster (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The impact of body mass index (BMI; kg/m2) and waist circumference (WC) on mortality in elderly individuals is controversial and previous research has largely focused on obesity. With special attention to the lower BMI categories, associations between BMI and both total and cause-specific mortality were explored in 7604 men and 9107 women aged ≥65 years who participated in the Tromsø Study (1994–1995) ...

    • Botulinum Toxin A in the treatment of frostbite sequelae–results from a blinded, early-phase, comparative trial 

      Norheim, Arne Johan; Borud, Einar Kristian; Mercer, James; de Weerd, Louis; Weiss, Thomas; Wilsgaard, Tom (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-15)
      Introduction: Freezing Cold Injuries (FCI) have been associated with long-term sequelae including vasospasm. The aims of the pilot study are to explore the research methodology and investigate the tolerability and safety of treatment with Botulinum Toxin-A (BTX-A) in FCI Sequelae. Methodology: This pilot study tests the logistics, the treatment setting and the follow-up procedure in an early-phase, ...

    • Burden of hip fracture using disability-adjusted life-years: a pooled analysis of prospective cohorts in the CHANCES consortium 

      Papadimitriou, Nikos; Tsilidis, Konstantinos K.; Orfanos, Philippos; Benetou, Vassiliki; Ntzani, Evangelia E.; Soerjomataram, Isabelle; Künn-Nelen, Annemarie; Pettersson-Kymmer, Ulrika; Eriksson, Sture; Brenner, Hermann; Schöttker, Ben; Saum, Kai-Uwe; Holleczek, Bernd; Grodstein, Francine D.; Feskanich, Diane; Orsini, Nicola; Wolk, Alicja; Bellavia, Andrea; Wilsgaard, Tom; Jørgensen, Lone; Boffetta, Paolo; Trichopoulos, Dimitrios; Trichopoulou, Antonia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-11)
      <p><i>Background</i>: No studies have estimated disability-adjusted life-years (DALYs) lost due to hip fractures using real-life follow-up cohort data. We aimed to quantify the burden of disease due to incident hip fracture using DALYs in prospective cohorts in the CHANCES consortium, and to calculate population attributable fractions based on DALYs for specific risk factors.</p> <p><i>Methods</i>: ...

    • Cardiovascular health and the modifiable burden of incident myocardial infarction: The Tromsø Study 

      Wilsgaard, Tom; Loehr, LR; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Bønaa, Kaare Harald; Njølstad, Inger; Heiss, G (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-06)
      Background: The American Heart Association has proposed an impact goal for the year 2020 to improve cardiovascular health by 20%. The objectives of the study were to assess the association between the proposed cardiovascular health metric score and incident myocardial infarction (MI) and to estimate the generalized impact fraction (GIF). <p>Methods: The health metric score was derived from ideal ...

    • Change in cardiovascular risk assessment tool and updated Norwegian guidelines for cardiovascular disease in primary prevention increase the population proportion at risk: The Tromsø Study 2015-2016 

      Nilsen, Amalie; Hanssen, Tove Aminda; Lappegård, Knut Tore; Eggen, Anne Elise; Løchen, Maja-Lisa; Selmer, Randi Marie; Njølstad, Inger; Wilsgaard, Tom; Hopstock, Laila Arnesdatter (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-30)
      Aims - To compare the population proportion at high risk of cardiovascular disease (CVD) using the Norwegian NORRISK 1 that predicts 10-year risk of CVD mortality and the Norwegian national guidelines from 2009, with the updated NORRISK 2 that predicts 10-year risk of both fatal and non-fatal risk of CVD and the Norwegian national guidelines from 2017.<p> <p>Methods - We included participants ...

    • The Clinical Effectiveness of Web-Based Cognitive Behavioral Therapy With Face-to-Face Therapist Support for Depressed Primary Care Patients: Randomized Controlled Trial 

      Høifødt, Ragnhild Sørensen; Lillevoll, Kjersti; Griffiths, Kathleen M; Wilsgaard, Tom; Eisemann, Martin; Waterloo, Knut; Kolstrup, Nils (Journal article; Tidsskriftartikkel; Peer reviewed, 2013-08-05)

    • Cohort profile: The Tromsø Study 

      Jacobsen, Bjarne Koster; Eggen, Anne Elise; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Njølstad, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The Tromsø Study was initiated in 1974 in an attempt to help combat the high mortality of cardiovascular diseases in Norway, that was particularly pronounced among middle-aged men. In the mid-1970s, Norwegian men had a 20% risk of dying of myocardial infarction (MI) before the age of 75 years. The situation in Northern Norway was even worse.1 The primary aim of the Tromsø Study was to determine ...

    • Collagen-covered autologous chondrocyte implantation versus autologous matrix-induced chondrogenesis: A randomized trial comparing 2 methods for repair of cartilage defects of the knee 

      Fossum, Vegard; Hansen, Ann Kristin; Wilsgaard, Tom; Knutsen, Gunnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-17)
      <i>Background</i>: Autologous matrix-induced chondrogenesis (AMIC) is a single-stage alternative to autologous chondrocyte implantation for treatment of localized cartilage defects of the knee. To our knowledge, no randomized controlled trial exists comparing the 2 methods.<p><p> <i>Purpose</i>: To evaluate any difference in the outcome of AMIC as compared with collagen-covered autologous chondrocyte ...

    • Combined Influence of Waist and Hip Circumference on Risk of Death in a Large Cohort of European and Australian Adults 

      Cameron, Adrian J.; Romaniuk, Helena; Orellana, Liliana; Dallongeville, Jean; Dobson, Annette J; Drygas, Wojciech; Ferrario, Marco; Ferrieres, Jean; Giampaoli, Simona; Gianfagna, Francesco; Iacoviello, Licia; Jousilahti, Pekka; Kee, Frank; Moitry, Marie; Niiranen, Teemu J; Pajak, Andrzej; Palmieri, Luigi; Palosaari, Tarja; Mannisto, Satu; Tamosiunas, Abdonas; Thorand, Barbara; Toft, Ulla; Vanuzzo, Diego; Salomaa, Veikko; Veronesi, Giovanni; Wilsgaard, Tom; Kuulasmaa, Kari; Söderberg, Stefan (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)
      Background - Waist circumference and hip circumference are both strongly associated with risk of death; however, their joint association has rarely been investigated.<p> <p>Methods and Results - The MONICA Risk, Genetics, Archiving, and Monograph (MORGAM) Project was conducted in 30 cohorts from 11 countries; 90 487 men and women, aged 30 to 74 years, predominantly white, with no history of ...

    • Comparing the sociodemographic characteristics of participants and non-participants in the population-based Tromsø Study 

      Vo, Chi Quynh; Samuelsen, Per-Jostein; Sommerseth, Hilde Leikny; Wisløff, Torbjørn; Wilsgaard, Tom; Eggen, Anne Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-29)
      Background Diferences in the sociodemographic characteristics of participants and non-participants in populationbased studies may introduce bias and reduce the generalizability of research fndings. This study aimed to compare the sociodemographic characteristics of participants and non-participants of the seventh survey of the Tromsø Study (Tromsø7, 2015–16), a population-based health survey.<p> ...

    • Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: Meta-analysis of individual participant data of seven prospective cohorts in Europe 

      Freisling, Heinz; Arnold, Melina; Soerjomataram, Isabelle; O'Doherty, Mark George; Ordóñez-Mena, José Manuel; Bamia, Christina; Kampman, Ellen; Leitzmann, Michael; Romieu, Isabelle; Kee, Frank; Tsilidis, Konstantinos; Tjønneland, Anne; Trichopoulou, Antonia; Boffetta, Paolo; Benetou, Vassiliki; Bueno-De-Mesquita, Hendrik Bastiaan; Huerta, José María; Brenner, Hermann; Wilsgaard, Tom; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-25)

    • Continuing increased risk of second cancer in long-term testicular cancer survivors after treatment in the cisplatin era 

      Hellesnes, Ragnhild; Kvammen, Øivind; Myklebust, Tor Åge; Bremnes, Roy M.; Karlsdottir, Åsa; Negaard, Helene Francisca Stigter; Tandstad, Torgrim; Wilsgaard, Tom; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-09)
      Using complete information on total treatment burden, this population‐based study aimed to investigate second cancer (SC) risk in testicular cancer survivors (TCS) treated in the cisplatin era. The Cancer Registry of Norway identified 5,625 1‐year TCS diagnosed 1980–2009. Standardized incidence ratios (SIRs) were calculated to evaluate the total and site‐specific incidence of SC compared to the ...

    • Cost-Effectiveness of Telemedicine in Remote Orthopedic Consultations: Randomized Controlled Trial 

      Buvik, Astrid Synnøve; Bergmo, Trine Strand; Bugge, Einar; Småbrekke, Arvid; Wilsgaard, Tom; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-19)
      <p><i>Background</i>: Telemedicine consultations using real-time videoconferencing has the potential to improve access and quality of care, avoid patient travels, and reduce health care costs.</p> <p><i>Objective</i>: The aim of this study was to examine the cost-effectiveness of an orthopedic videoconferencing service between the University Hospital of North Norway and a regional medical center ...

    • Cystatin C and cardiovascular disease: a Mendelian randomization study 

      van der Laan, Sander W; Fall, Tove; Sourmare, Aicha; Teumer, Alexander; Sedaghat, Sanaz; Baumert, Jens; Zahaneh, Delilah; van Setten, Jessica; Isgum, Ivana; Galesloot, Tessel E.; Arpegård, Johannes; Amouyel, Philippe; Trompet, Stella; Waldenberger, Melanie; Dörr, Marcus; Magnusson, Patrik K.; Giedraitis, Vilmantas; Larsson, Anders; Morris, Andrew P.; Felix, Janine F.; Morrison, Alanna C.; Franceschini, Nora; Bis, Joshua C.; Kavousi, Maryam; O'Donnell, Christopher J.; Drenos, Fotios; Tragante, Vinicius; Munroe, Patricia B.; Malik, Rainer; Dichgans, Martin; Worrall, Bradford B.; Erdmann, Jeanette; Nelson, Christopher P.; Samani, Nilesh J.; Schunkert, Heribert; Marchini, Jonathan; Patel, Riyaz S.; Hingorani, Aroon D.; Lind, Lars; Pedersen, Nancy L.; de Graaf, Jacqueline; Kiemeney, Lambertus A.L.M.; Baumeister, Sebastian E.; Franco, Oscar H.; Hofman, Albert; Uitterlinden, André G.; Koenig, Wolfgang; Meisinger, Christa; Peters, Annette; Thorand, Barbara; Jukema, J.Wouter; Eriksen, Bjørn Odvar; Toft, Ingrid; Wilsgaard, Tom; Onland-Moret, N. Charlotte; van der Schouw, Yvonne T.; Debette, Stéphanie; Kumari, Meena; Svensson, Per; van der Harst, Pim; Kivimäki, Mika; Keating, Brendan J.; Sattar, Naveed; Dehghan, Abbas; Reiner, Alex P.; Ingelsson, Erik; Den Ruijter, Hester M.; de Bakker, Paul I.W.; Pasterkamp, Gerard; Ärnlöv, Johan; Holmes, Michael V.; Asselbergs, Folkert W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-08-30)
      BACKGROUND<br> Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based renal function measurements. It is unclear whether this relationship is causal, arises from residual confounding, and/or is a consequence of reverse causation.<br> OBJECTIVES<br>The aim of this study was to use Mendelian randomization ...

    • Data from national health registers as endpoints for the Tromsø Study: Correctness and completeness of stroke diagnoses 

      Varmdal, Torunn; Løchen, Maja-Lisa; Wilsgaard, Tom; Njølstad, Inger; Nyrnes, Audhild; Grimsgaard, Sameline; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-14)
      Aim: To assess whether stroke diagnoses in national health registers are sufficiently correct and complete to replace manual collection of endpoint data for the Tromsø Study, a population-based epidemiological study.<p> <p>Method: Using the Tromsø Study Cardiovascular Disease Register for 2013–2014 as the gold standard, we calculated correctness (defined as positive predictive value, PPV) and ...

    • Data on gender contrasts in the risk of incident myocardial infarction by age. The Tromsø Study 1979–2012 

      Albrektsen, Grethe; Heuch, Ivar; Løchen, Maja-Lisa; Thelle, Dag Steinar; Wilsgaard, Tom; Njølstad, Inger; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-08)
      The data presented in this article relate to the research article entitled “Risk of incident myocardial infarction by gender: Interactions with serum lipids, blood pressure and smoking. The Tromsø Study 1979–2012” (Albrektsen et al., 2017) [1]. Data quantify the gender differences in the risk of myocardial infarction (MI) in terms of incidence rate ratios (IRR), in subgroups defined by serum lipids, ...

    • The DBP Phenotype Gc-1f/Gc-1f is associated with reduced risk of cancer. The Tromsø Study 

      Jorde, Rolf; Schirmer, Henrik; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Løchen, Maja-Lisa; Joakimsen, Ragnar Martin; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-18)
      Background and Objective In addition to its role as a transport protein, the vitamin D binding protein (DBP) may also affect lipid metabolism, inflammation and carcinogenesis. There are three common variants of the DBP, Gc1s (1s), Gc1f (1f), Gc2 (2) that result in six common phenotypes (1s/1s, 1s/ 1f, 1s/2, 1f/1f, 1f/2, and 2/2). These phenotypes can be identified by genotyping for the two single ...