Infections due to carbapenemase-producing Gram-negative pathogens are associated with limited treatment options and consequently lead to increased mortality and morbidity. In response, combinations of existing β-lactams and novel β-lactamase inhibitors, such as ceftazidime-avibactam (CAZ-AVI), have been developed as alternative treatment options. To understand the development of resistance and ...

A recent study on magnetically induced currents in 10-isocorrole derivatives indicated that both the free-base and metal-complexed forms of the unsubstituted macrocycle are homoaromatic. Furthermore, depending on the substituents at the 10-position, the aromatic character was found to swing between substantially homoaromatic to substantially antihomoaromatic. Heteroisocorroles, in which the saturated ...

The purpose of this article is to discuss the concept of “indigenous education” in Norway and Aotearoa New Zealand. The point of departure is that both states face a common challenge with regard to indigenous education: Valuable resources are used on indigenous schools, but the majority of indigenous students attend mainstream schools. The article claims that the emphasis on indigenous schools has ...

<i>Background</i>: The coordination of group behaviors in bacteria is achieved by a cell-cell signaling process called quorum sensing (QS). QS is an intercellular communication system, which synchronously controls expression of a vast range of genes in response to changes in cell density and is mediated by autoinducers that act as extracellular signals. <i>Aliivibrio salmonicida</i>, the causative ...

<i>Background</i>: Rapid and precise dispatch of resources is a key element in pre‐hospital emergency medicine. Emergency medical communication centres (EMCCs) dispatch resources based on protocols and guidelines, balancing the acute need of the individual and the resource allocation of the pre‐hospital emergency medical system. The aim of this study was to determine the validity of stroke ...

Goals are central to theories of happiness and previous research has shown that successful goal pursuit typically leads to a boost in wellbeing. Taking these ideas further, the current study adopts the distinction between hedonic wellbeing (HWB) and eudaimonic wellbeing (EWB) and suggests that it is the former that increases when goals are achieved. By contrast, EWB is hypothesized to have a causal ...

<p>During the late nineteenth century two neighbouring peasants, Anders Nilsson and Johannes Persson, lived in the small village of Kroppåkra in southern Sweden. They were both landowning peasants, both were married men and had several children. What is more, they were both members of the local parochial library. The library was established in 1859 on a local initiative, and was jointly owned by the ...

Although separate titles in their own right, these two books, The Swedish Hymnbook and a collection of Biblical passages for all Sundays and Holy Days, are seen so often together that they can rightfully be called the yin and yang of the early modern Swedish book market. Bestsellers in their time, with new editions coming every other year, they were a must-have for both wealthy and poor. This blog ...

<p>Hvordan bidrar etnografisk film til antropologisk forståelse? Hva er likheter og forskjeller i perspektiver og metoder i etnografiske filmopptak og en mer konvensjonell antropologi? Film og tekst er to ulike representasjonsformer med ulike styrker og svakheter. Jeg vil her argumentere for at det i møtet mellom den i utgangspunktet tekstbaserte situasjonsanalysen, slik den formuleres av Manchesterskolen, ...

The present work reports on new mineralogical and whole-rock geochemical data from the Breivikbotn silicocarbonatite (Seiland igneous province, North Norway), allowing conclusions to be drawn concerning its origin and the role of late fluid alteration. The rock shows a rare mineral association: calcite + pyroxene + amphibole + zeolite group minerals + garnet + titanite, with apatite, allanite, ...