• High prevalence of echocardiographic abnormalities in older HIV-infected children taking antiretroviral therapy 

      Majonga, Edith D.; Rehman, Andrea M.; Simms, Victoria; McHugh, Grace; Mujuru, Hilda A.; Nathoo, Kusum; Odland, Jon Øyvind; Patel, Mohammad S.; Kaski, Juan P.; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-28)
      Background: Antiretroviral therapy (ART) has decreased mortality so that increasing numbers of children with HIV are reaching adolescence. However, longstanding HIV infection and/or its treatment in children is associated with noninfectious complications including cardiac disease. We investigated the prevalence, spectrum and risk factors for echocardiographic abnormalities among children established ...
    • History of tuberculosis is associated with lower exhaled nitric oxide levels in HIV-infected children 

      Sovershaeva, Evgeniya; Kranzer, Katharina; McHugh, Grace; Bandason, Tsitsi; Majonga, Edith D.; Usmani, Omar S.; Rowland-Jones, Sarah; Gutteberg, Tore Jarl; Flægstad, Trond; Ferrand, Rashida A.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-01)
      <p><i>Objective - </i>HIV disrupts host defense mechanisms and maintains chronic inflammation in the lung. Nitric oxide is a marker of lung inflammation and can be measured in the exhaled air. We investigated the relationship between exhaled nitric oxide (eNO), HIV status and airway abnormalities in perinatally HIV-infected children aged 6–19 years. <p><i>Design - </i>A cross-sectional study. <p ...
    • The impact of long-term azithromycin on antibiotic resistance in HIV-associated chronic lung disease 

      Abotsi, Regina E.; Nicol, Mark P.; McHugh, Grace; Simms, Victoria; Rehman, Andrea M.; Barthus, Charmaine; Ngwira, Lucky G.; Kwambana-Adams, Brenda; Heyderman, Robert S.; Odland, Jon Øyvind; Ferrand, Rashida A.; Dube, Felix S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-07)
      Selection for resistance to azithromycin (AZM) and other antibiotics such as tetracyclines and lincosamides remains a concern with long-term AZM use for treatment of chronic lung diseases (CLD). We investigated the impact of 48 weeks of AZM on the carriage and antibiotic resistance of common respiratory bacteria among children with HIV-associated CLD. Nasopharyngeal (NP) swabs and sputa were ...
    • The impacts of emission trends of POPs on human concentration dynamics: Lessons learned from a longitudinal study in Norway (1979-2007) 

      Nøst, Therese Haugdahl; Sandanger, Torkjel M; Nieboer, Evert; Odland, Jon Øyvind; Breivik, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-02-20)
      Background. In this short communication, our focus is on the relationship between human concentrations of select persistent organic pollutants (POPs) and environmental emissions. It is based on a longitudinal study (1979-2007) conducted in Norway. Objectives. Our aim was to extract general insights from observed and predicted temporal trends in human concentrations of 49 POPs to assist in the design ...
    • Incidence and Risk Factors of Pre-Eclampsia in the Paropakar Maternity and Women's Hospital, Nepal: A Retrospective Study 

      Das, Seema; Das, Rupesh; Bajracharya, Rashmita; Baral, Gehanath; Jabegu, Bina; Odland, Jon Øyvind; Odland, Maria Lisa (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      This study aims to determine the incidence of pre-eclampsia and distribution of risk factors of pre-eclampsia at Paropakar Maternity and Women’s Hospital, Kathmandu, Nepal. A retrospective study included 4820 pregnant women from 17 September to 18 December 2017. Data were obtained from the medical records of the hospital’s Statistics Department. Associations between the risk factors and pre-eclampsia ...
    • Key indicators of obstetric and neonatal care in the Republic of Sakha (Yakutia) 

      Burtseva, Tatyana E; Odland, Jon Øyvind; Douglas, Natalya I; Grigoreva, Antonina N; Pavlova, Tatyana Y; Chichahov, Dgulustan A; Afanasieva, Lena N; Baisheva, Nurguyana S; Rad, Yana G; Tomsky, Mikhail I; Postoev, Vitaly Alexandrovich (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-13)
      In the absence of a medical birth registry, the official statistics are the only sources of information about pregnancy outcomes in the Republic of Sakha (Yakutia) (RS). We analysed the official statistical data about birth rate, fertility, infant and maternal mortality in the RS in the period 2003-2014. Compared with all- Russian data, the RS had a higher birth rate, especially in rural districts. ...
    • Knowledge about human papillomavirus and prevention of cervical cancer among women of Arkhangelsk, Northwest Russia 

      Roik, Elena Evgenievna; Sharashova, Ekaterina; Nieboer, Evert; Kharkova, Olga Alexandrovna; Postoev, Vitalij A.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-13)
      <p><i>Background - </i>Knowledge about cervical cancer (CC) risk factors and benefits of CC prevention motivates women to participate in its screening. However, several studies show that there is a significant knowledge deficit worldwide about human papillomavirus (HPV). The current study explores the level of knowledge about HPV and CC prevention in the context of sociodemographic and behavioral ...
    • Levels and trends of contaminants in humans of the Arctic 

      Gibson, Jennifer; Adlard, Bryan; Olafsdottir, Kristin; Sandanger, Torkjel M; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-13)
      The Arctic Monitoring and Assessment Programme (AMAP) is one of the six working groups established under the Arctic Council. AMAP is tasked with monitoring the levels of contaminants present in the Arctic environment and people as well as assessing their effects on a continuous basis, and reporting these results regularly. Most of the presented data have been collected over the last 20 years and are ...
    • Maternal Risk Factors for Preterm Birth in Murmansk County, Russia: A Registry-Based Study 

      Usynina, Anna Alexandrovna; Postoev, Vitaly Alexandrovich; Grjibovski, Andrej; Krettek, Alexandra; Nieboer, Evert; Odland, Jon Øyvind; Anda, Erik Eik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      Background: Globally, about 11% of all liveborn infants are preterm. To date, data on prevalence and risk factors of preterm birth (PTB) in Russia are limited. The aims of this study were to estimate the prevalence of PTB in Murmansk County, Northwestern Russia and to investigate associations between PTB and selected maternal factors using the Murmansk County Birth Registry. Methods: We conducted ...
    • Maternal serum levels of perfluoroalkyl substances and organochlorines and indices of fetal growth: a Scandinavian case-cohort study 

      Lauritzen, Hilde Brun; Larose, Tricia L; Øien, Torbjørn; Sandanger, Torkjel M; Odland, Jon Øyvind; van de Bor, Margot; Jacobsen, Geir Wenberg (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-26)
      <b>Background:</b> The associations between prenatal exposure to endocrine disruptive chemicals (EDCs) and fetal growth are inconsistent, and few studies have considered small-for-gestational-age (SGA) birth as an outcome. Our current study of Scandinavian parous women aimed to address these inconsistencies and gaps in the literature.<br> <b>Methods:</b> This case–cohort study included 424 ...
    • MercuNorth – monitoring mercury in pregnant women from the Arctic as a baseline to assess the effectiveness of the Minamata Convention 

      Adlard, Bryan; Lemire, Mélanie; Bonefeld-Jørgensen, Eva Cecilie; Long, Manhai; Ólafsdóttir, Kristín; Odland, Jon Øyvind; Rautio, Arja; Myllynen, Päivi; Sandanger, Torkjel M; Dudarev, Alexey A.; Bergdahl, Ingvar A.; Wennberg, Maria; Berner, James; Ayotte, Pierre (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-03)
      Exposure to mercury (Hg) is a global concern, particularly among Arctic populations that rely on the consumption of marine mammals and fish which are the main route of Hg exposure for Arctic populations.The MercuNorth project was created to establish baseline Hg levels across several Arctic regions during the period preceding the Minamata Convention. Blood samples were collected from 669 pregnant ...
    • The Northern Norway mother-and-child contaminant cohort study: implementation, population characteristics and summary of dietary findings 

      Veyhe, Anna Sofia; Hansen, Solrunn; Sandanger, Torkjel Manning; Nieboer, Evert; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-05-28)
      <p><i>Objectives.</i> To describe the essential features of a new Northern Norway mother-and-child contaminant cohort study called MISA, including its rationale, content, implementation and selected findings (mostly dietary). <p><i>Study design. </i>Cross-sectional with longitudinal aspects. <p><i>Methods.</i> Five hundred and fifteen eligible women were enrolled in early pregnancy, with 391 ...
    • Occupational Medicine and Environmental Health in the Border Areas of Euro-Arctic Barents Region: A Review of 30-Year Russian–Norwegian Research Collaboration Outcomes 

      Chashchin, Valery; Gorbanev, Sergei; Thomassen, Yngvar; Nieboer, Evert; Ellingsen, Dag; Syurin, Sergei; Nikanov, Alaksandr; Chashchin, Max; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-30)
      This year marks 30 years of close collaboration between a consortium of institutions, namely, the Northwest Public Health Research Center, Saint-Petersburg (NWPHRC); the Institute of Community Medicine (ICM) of UiT (The Arctic University of Norway, Tromsø); the National Institute of Occupational Health (NIOH), Oslo; the University Hospital of Northern Norway (UNN) at Tromsø; and McMaster University ...
    • Overview of human health in the Arctic: conclusions and recommendations 

      Donaldson, Shawn; Adlard, Bryan; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-23)
      This article is intended to provide an overview of the key conclusions, knowledge gaps and key recommendations based on the recent 2015 Arctic human health assessment under the Arctic Monitoring and Assessment Program. This assessment was based primarily on data from human health monitoring and research studies and peer-reviewed literature published since the last assessment in 2009.
    • Overview of ongoing cohort and dietary studies in the Arctic 

      Weihe, Pál; Bjerregaard, Peter; Bonefeld-Jørgensen, Eva; Dudarev, Alexey; Halling, Jónrit; Hansen, Solrunn; Muckle, Gina; Nøst, Therese Haugdahl; Odland, Jon Øyvind; Petersen, Maria Skaalum; Rautio, Arja; Veyhe, Anna Sofia; Wennberg, Maria; Bergdahl, Ingvar (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-23)
      This article gives an overview of the ongoing cohort and dietary studies underlying the assessment of population health in the Arctic. The emphasis here is on a description of the material, methods and results or preliminary results for each study. Detailed exposure information is available in an article in this journal, whereas another paper describes the effects associated with contaminant ...
    • Patterns of detectable viraemia among children and adults with HIV infection taking antiretroviral therapy in Zimbabwe 

      Sovershaeva, Evgeniya; Shamu, Tinei; Wilsgaard, Tom; Bandason, Tsitsi; Flægstad, Trond; Katzenstein, David; Ferrand, Rashida A.; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-31)
      <i>Objective</i>: To investigate the incidence and predictors of viraemia among individuals on antiretroviral therapy (ART) in Harare, Zimbabwe.<p> <p><i>Methods</i>: Children (0–19 years) and adults (>19 years) starting ART between 2013 and 2015 were followed for a median of 2.8 and 2.7 years, respectively. The incidence rates of virological failure (VF), low-level viraemia (LLV), and viral ...
    • Persistent Organic Pollutants and the Association with Maternal and Infant Thyroid Homeostasis: A Multipollutant Assessment 

      Berg, Vivian; Nøst, Therese Haugdahl; Pettersen, Rolf Dagfinn; Hansen, Solrunn; Veyhe, Anna Sofia; Jorde, Rolf; Odland, Jon Øyvind; Sandanger, Torkjel M (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01)
      Background:<br>Disruption of thyroid homeostasis has been indicated in human studies targeting effects of persistent organic pollutants (POPs). Influence on the maternal thyroid system by POPs is of special interest during pregnancy because such effects could impair infant thyroid homeostasis.<br> Objectives:<br>We investigated the association between POPs and thyroid-stimulating hormone (TSH) ...
    • Polychlorinated biphenyls (PCBs) as sentinels for the elucidation of Arctic environmental change processes: a comprehensive review combined with ArcRisk project results 

      Carlsson, Pernilla; Breivik, Knut; Brorström-Lundén, Eva; Cousins, Ian; Christensen, Jesper; Grimalt, Joan O.; Halsall, Crispin; Kallenborn, Roland; Abass, Khaled; Lammel, Gerhard; Munthe, John; MacLeod, Matthew; Odland, Jon Øyvind; Pawlak, Janet; Rautio, Arja; Reiersen, Lars-Otto; Schlabach, Martin; Stemmler, Irene; Wilson, Simon; Wöhrnschimmel, Henry (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-28)
      Polychlorinated biphenyls (PCBs) can be used as chemical sentinels for the assessment of anthropogenic influences on Arctic environmental change. We present an overview of studies on PCBs in the Arctic and combine these with the findings from ArcRisk—a major European Union-funded project aimed at examining the effects of climate change on the transport of contaminants to and their behaviour of in ...
    • Prenatal Exposure to Aluminum and Status of Selected Essential Trace Elements in Rural South AfricanWomen at Delivery 

      Rollin, Halina B.; Nogueira, Claudina; Olutola, Bukola G; Channa, Kalavati; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-15)
      This study sought to evaluate the in utero exposure to aluminum and status of selected trace elements in South African women at delivery since aluminum is known to be toxic in all developmental stages even at low concentrations. Serum aluminum was negatively correlated with aluminum in urine, both uncorrected and corrected for creatinine, which suggests the retention of aluminum in body stores. ...
    • Prenatal exposure to cadmium, placental permeability and birth outcomes in coastal populations of South Africa 

      Röllin, Halina B.; Kootbodien, Tahira; Channa, Kalavati; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-06)
      Background The impact of prenatal exposure to cadmium (Cd) on birth outcomes is an area of concern. This study aimed to assess an impact of prenatal Cd exposure on birth outcomes in distinct coastal populations of South Africa. <p>Methods Cadmium was measured in maternal blood (CdB) (n = 641), cord blood and in maternal urine (n = 317). This investigation assessed the associations between CdB ...