Now showing items 1052-1071 of 1394

    • Prevention of obstetric anal sphincter injuries with perineal support and lateral episiotomy: A historical cohort study 

      Eggebø, Torbjørn Moe; Rygh, Astrid; von Brandis, Phillip; Skjeldestad, Finn egil (Journal article; Tidsskriftartikkel, 2023-12-05)
      <p><i>Introduction</i> - There are many risk factors for obstetric anal sphincter injury (OASIS) and the interaction between these risk factors is complex and understudied. The many observational studies that have shown a reduction of OASIS rates after implementation of perineal support have short follow-up time. We aimed to study the effect of integration of active perineal support and lateral ...
    • Primary care emergency team training in situ means learning in real context 

      Brandstorp, Helen; Halvorsen, Peder Andreas; Sterud, Birgitte; Haugland, Bjørgun; Kirkengen, Anna Luise (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-21)
      <b>Objective:</b> The purpose of our study was to explore the local learning processes and to improve in situ team training in the primary care emergency teams with a focus on interaction.<br> <b>Design, setting and subjects:</b> As participating observers, we investigated locally organised trainings of teams constituted ad hoc, involving nurses, paramedics and general practitioners, in rural Norway. ...
    • Primary care use and cardiovascular disease risk in Russian 40–69 year olds: a cross-sectional study 

      Petersen, Jakob; Kontsevaya, Anna V.; McKee, Martin; Richardson, E.; Cook, Sarah Anne; Malyutina, Sofia; Kudryavtsev, Alexander V; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-04)
      <i>Background</i> - The Russian Federation has very high cardiovascular disease (CVD) mortality rates compared with countries of similar economic development. This cross-sectional study compares the characteristics of CVD-free participants with and without recent primary care contact to ascertain their CVD risk and health status.<br><br> <i>Methods</i> - A total of 2774 participants aged 40–69 ...
    • Primærhelseteam – en mer teambasert fastlegetjeneste 

      Pedersen, Kine; Løyland, Hanna Isabel; Erik Magnus, Sæther; Sten Gahmberg, Susanna; Abelsen, Birgit; Snilsberg, Øyvind; Iversen, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-29)
      Primærhelseteam (PHT) er en ny arbeidsform i fastlegetjenesten der lege, sykepleier og helsesekretær jobber sammen i team. Teamet skal tilby gode tjenester og arbeide systematisk med pasientsikkerhet og kvalitetsforbedring. Målgruppene for primærhelseteam er listeinnbyggere med kronisk sykdom, psykiske lidelser og rusavhengighet, skrøpelige eldre, og brukere med utviklingshemming og funksjonsnedsettelser. ...
    • A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape 

      Ried, Janina S.; Jeff, Janina M.; Chu, Audrey Y.; Bragg-Gresham, Jennifer L.; Van Dongen, Jenny; Huffman, Jennifer E.; Ahluwalia, Tarunveer S.; Cadby, Gemma; Eklund, Niina; Eriksson, Joel; Esko, Tonu; Feitosa, Mary F.; Goel, Anuj; Gorski, Mathias; Hayward, Caroline; Heard-Costa, Nancy L.; Jackson, Anne U.; Jokinen, Eero; Kanoni, Stavroula; Kristiansson, Kati; Kutalik, Zoltan; Lahti, Jari; Luan, Jian'an; Mägi, Reedik; Mahajan, Anubha; Mangino, Massimo; Medina-Gomez, Carolina; Monda, Keri L.; Nolte, Ilja M.; Perusse, Louis; Prokopenko, Inga; Qi, Lu; Rose, Lynda M.; Salvi, Erika; Smith, Megan T.; Snieder, Harold; Standakova, Alena; Ju Sung, Yun; Tachmazidou, Ioanna; Teumer, Alexander; Thorleifsson, Gudmar; Van Der Harst, Pim; Walker, Ryan W.; Wang, Sophie R.; Wild, Sarah H.; Willems, Stefan M.; Wong, Andrew; Zhang, Weihua; Albrecht, Eva; Couto Alves, Alexessander; Bakker, Stephan J.L.; Barlassina, Cristina; Bartz, Traci M.; Beilby, John; Bellis, Claire; Bergman, Richard N; Bergmann, Sven; Blangero, John; Bluher, Matthias; Boerwinkle, Eric; Bonnycastle, Lori L.; Bornstein, Stefan R.; Bruinenberg, Marcel; Campbell, Harry; Chen, Yii-Der Ida; Chiang, Charleston W.K.; Chines, Peter S.; Collins, Francis S.; Cucca, Fracensco; Cupples, L. Adrienne; D'avila, Francesca; de Geus, Eco J.C.; Dedoussis, George; Dimitriou, Maria; Döring, Angela; Eriksson, Johan G.; Farmaki, Aliki-Eleni; Farrall, Martin; Ferreira, Teresa; Fischer, Krista; Forouhi, Nita G.; Friedrich, Nele; Gjesing, Anette Prior; Glorioso, Nicola; Graff, Mariaelisa; Grallert, Harald; Grarup, Niels; Gräßler, Jurgen; Grewal, Jagvir; Hamsten, Anders; Harder, Marie Neergaard; Hartman, Catharina A.; Hassinen, Maija; Hastie, Nicholas; Hattersley, Andrew Tym; Havulinna, Aki S.; Heliövaara, Markku; Hillege, Hans; Hofman, Albert; Holmen, Oddgeir; Homuth, Georg; Hottenga, Jouke-Jan; Hui, Jennie; Husemoen, Lise Lotte; Hysi, Pirro G; Isaacs, Aaron; Ittermann, Till; Jalilzadeh, Shapour; James, Alan L; Jørgensen, Torben; Jousilahti, Pekka; Jula, Antti; Marie Justesen, Johanne; Justice, Anne E; Kähönen, Mika; Karaleftheri, Maria; Tee Khaw, Kay; Keinanen-Kiukaanniemi, Sirkka M; Kinnunen, Leena; Knekt, Paul B; Koistinen, Heikki A; Kolcic, Ivana; Kooner, Ishminder K; Koskinen, Seppo; Kovacs, Peter; Kyriakou, Theodosios; Laitinen, Tomi; Langenberg, Claudia; Lewin, Alexandra M; Lichtner, Peter; Lindgren, Cecilia M; Lindström, Jaana; Linneberg, Allan; Lorbeer, Roberto; Lorentzon, Mattias; Luben, Robert; Lyssenko, Valeriya; Männistö, Satu; Manunta, Paolo; Leach, Irene Mateo; Mcardle, Wendy L; Mcknight, Barbara; Mohlke, Karen L; Mihailov, Evelin; Milani, Lili; Mills, Rebecca; Montasser, May E; Morris, Andrew P; Muller, Gabriele; Musk, Arthur W; Narisu, Narisu; Ong, Ken K; Oostra, Ben A; Osmond, Clive; Palotie, Aarno; Pankow, James S; Paternoster, Lavinia; Penninx, Brenda W; Pichler, Irene; Pilia, Maria G; Polasek, Ozren; Pramstaller, Peter P; Raitakari, Olli T; Rankinen, Tuomo; Rao, DC; Rayner, Nigel W; Ribel-Madsen, Rasmus; Rice, Treva K; Richards, Marcus; Ridker, Paul M; Rivadeneira, Fernando; Ryan, Kathy A; Sanna, Serena; Sarzynski, Mark A; Scholtens, Salome; Scott, Robert A; Sebert, Sylvain; Southam, Lorraine; Sparsø, Thomas Hempel; Steinthorsdottir, Valgerdur; Stirrups, Kathleen; Stolk, Ronald P; Strauch, Konstantin; Stringham, Heather M; Swertz, Morris A; Swift, Amy J; Tönjes, Anke; Tsafantakis, Emmanouil; Van Der Most, Peter J; Van Vliet-Ostaptchouk, Jana V; Vandenput, Liesbeth; Vartiainen, Erkki; Venturini, Cristina; Verweij, Niek; Viikari, Jorma S; Vitart, Veronique; Vohl, Marie-Claude; Vonk, Judith M; Waeber, Gerard; Widen, Elisabeth; Willemsen, Gonneke; Wilsgaard, Tom; Winkler, Thomas W; Wright, Alan F; Yerges-Armstrong, Laura M; Zhao, Jing Hua; Carola Zillikens, M; Boomsma, Dorret I; Bouchard, Claude; Chambers, John C; Chasman, Daniel I; Cusi, Daniele; Gansevoort, Ron T; Gieger, Christian; Hansen, Torben; Hicks, Andrew A; Hu, Frank; Hveem, Kristian; Jarvelin, Marjo-Riitta; Kajantie, Eero; Kooner, Jaspal S; Kuh, Diana; Kuusisto, Johanna; Laakso, Markku; Lakka, Timo A; Lehtimäki, Terho; Metspalu, Andres; Njølstad, Inger; Ohlsson, Claes; Oldehinkel, Albertine J; Palmer, Lyle J; Pedersen, Oluf; Perola, Markus; Peters, Annette; Psaty, Bruce M; Puolijoki, Hannu; Rauramaa, Rainer; Rudan, Igor; Salomaa, Veikko; Schwarz, Peter E H; Shudiner, Alan R; Smit, Jan H; Sørensen, Thorkild I A; Spector, Timothy D; Stefansson, Kari; Stumvoll, Michael; Tremblay, Angelo; Tuomilehto, Jaakko; Uitterlinden, Andre G; Uusitupa, Matti; Völker, Uwe; Vollenweider, Peter; Wareham, Nicholas J; Watkins, Hugh; Wilson, James F; Zeggini, Eleftheria; Abecasis, Goncalo R; Boehnke, Michael; Borecki, Ingrid B; Deloukas, Panos; Van Duijn, Cornelia M; Fox, Caroline; Groop, Leif C; Heid, Iris M; Hunter, David J; Kaplan, Robert C; Mccarthy, Mark I; North, Kari E; O'connell, Jeffrey R; Schlessinger, David; Thorsteinsdottir, Unnur; Strachan, David P; Frayling, Timothy; Hirschhorn, Joel N; Muller-Nurasyid, Martina; Loos, Ruth J.F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-23)
      Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that is represented by a combination of anthropometric traits. We developed an approach that calculates averaged PCs (AvPCs) representing body shape derived from six anthropometric traits (body mass index, ...
    • Priority setting for improvement of cervical cancer prevention in Iran 

      Majidi, Azam; Ghiasvand, Reza; Hadji, Maryam; Nahvijou, Azin; Mousavi, Azam-Sadat; Pakgohar, Minoo; Khodakarami, Nahid; Abedini, Mehrandokht; Hashemi, Farnaz Amouzegar; Farzami, Marjan Rahnamaye; Shahsiah, Reza; Sajedinejhad, Sima; Mohagheghi, Mohammad Ali; Nadali, Fatemeh; Rashidian, Arash; Weiderpass, Elisabete; Mogensen, Ole; Zendehdel, Kazem (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-22)
      Background:<br> Cervical cancer is the fourth most common cancer among women worldwide. Organized cervical screening and vaccination against human papilloma virus (HPV) have been successful interventions for prevention of invasive cervical cancer (ICC). Because of cultural and religious considerations, ICC has low incidence in Iran and many other Muslim countries. There is no organized cervical ...
    • Privacy-preserving architecture for providing feedback to clinicians on their clinical performance 

      Yigzaw, Kassaye Yitbarek; Budrionis, Andrius; Ruiz, Luis Marco; Henriksen, Torje Dahle; Halvorsen, Peder Andreas; Bellika, Johan Gustav (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-22)
      <i>Background</i> - Learning from routine healthcare data is important for the improvement of the quality of care. Providing feedback on clinicians’ performance in comparison to their peers has been shown to be more efficient for quality improvements. However, the current methods for providing feedback do not fully address the privacy concerns of stakeholders.<p><p> <i>Methods</i> - The paper ...
    • A Probabilistic Bag-to-Class Approach to Multiple-Instance Learning 

      Møllersen, Kajsa; Hardeberg, Jon Yngve; Godtliebsen, Fred (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
      Multi-instance (MI) learning is a branch of machine learning, where each object (bag) consists of multiple feature vectors (instances)—for example, an image consisting of multiple patches and their corresponding feature vectors. In MI classification, each bag in the training set has a class label, but the instances are unlabeled. The instances are most commonly regarded as a set of points in a ...
    • Probability revision in general practice: the cases of occult blood in stool in patients with indigestion, and daily smoking in patients who cough 

      Holtedahl, Knut A. (Journal article; Tidsskriftartikkel; Peer reviewed, 1990)
      Prior calculation of the sex- and age-distributed positive predictive value (PPV) of a symptom in relation to a disease forms the basis for probability revision based on new information about signals observed during the medical encounter: a symptom, a sign, a piece of information based on the medical history, a laboratory test. Probability revision requires estimates of sensitivity and specificity ...
    • Probing the differential tissue distribution and bioaccumulation behavior of per- and polyfluoroalkyl substances of varying chain-lengths, isomeric structures and functional groups in crucian carp 

      Shi, Yali; Vestergren, Robin; Nøst, Therese Haugdahl; Zhou, Zhen; Cai, Yaqi (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-03)
      Understanding the bioaccumulation mechanisms of per- and polyfluoroalkyl substances (PFASs) across different chain-lengths, isomers and functional groups represents a monumental scientific challenge with implications for chemical regulation. Here, we investigate how the differential tissue distribution and bioaccumulation behavior of 25 PFASs in crucian carp from two field sites impacted by point ...
    • A processual model for functional analyses of carcinogenesis in the prospective cohort design 

      Lund, Eiliv; Plancade, Sandra Caroline; Nuel, Gregory; Bøvelstad, Hege; Thalabard, Jean-Christophe (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)
      Traditionally, the prospective design has been chosen for risk factor analyses of lifestyle and cancer using mainly estimation by survival analysis methods. With new technologies, epidemiologists can expand their prospective studies to include functional genomics given either as transcriptomics, mRNA and microRNA, or epigenetics in blood or other biological materials. The novel functional analyses ...
    • Profesjonalitet i legeutdanningen: Om kunnskapskoder, praktiske synteser og koherens. En analyse av studieplanen for profesjonsstudiet i medisin ved Universitetet i Tromsø, Norges arktiske universitet 

      Hovdenak, Sylvi Stenersen; Risør, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Artikkelen analyserer revidert studieplan for profesjonsstudiet i medisin ved Universitetet i Tromsø, Norges arktiske universitet. Vi spør i hvilken grad og på hvilken måte den nye studieplanen ivaretar profesjonalitet. Praktiske synteser og koherens samt kunnskapskoder og kunnskapsformer danner et begrepsmessig utgangspunkt for analysen. Søkelyset rettes mot ulike kunnskapskoder der en ...
    • Progestin-only and combined oral contraceptives and receptor-defined premenopausal breast cancer risk: The Norwegian Women and Cancer Study 

      Busund, Marit Katinka; Stensland-Bugge, Nora; Braaten, Tonje; Waaseth, Marit; Rylander, Charlotta; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-19)
      Receptor-defined subtypes of breast cancer represent distinct cancer types and have differences in risk factors. Whether the two main hormonal forms of oral contraceptives (OCs); i.e. progestin-only (POC) and combined oral contraceptives (COC), are differentially associated with these subtypes are not well known. The aim of our study was to assess the effect of POC and COC use on hormone receptor-defined ...
    • The prognostic ease and difficulty of invasive breast carcinoma 

      Tofigh, Ali; Suderman, Matthew; Paquet, Eric R.; Livingstone, Julie; Bertos, Nicholas; Saleh, Sadiq M.; Zhao, Hong; Souleimanova, Margarita; Cory, Sean; Lesurf, Robert; Shahalizadeh, Solmaz; Garcia Lopez, Norberto; Riazalhosseini, Yasser; Omeroglu, Atilla; Ursini-Siegel, Josie; Park, Morag; Dumeaux, Vanessa; Hallett, Michael (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-02)
      Breast carcinoma (BC) has been extensively profiled by high-throughput technologies for over a decade, and broadly speaking, these studies can be grouped into those that seek to identify patient subtypes (studies of heterogeneity) or those that seek to identify gene signatures with prognostic or predictive capacity. The sheer number of reported signatures has led to speculation that everything ...
    • Prospective analysis of circulating metabolites and breast cancer in EPIC 

      His, Mathilde; Viallon, Vivian; Dossus, Laure; Gicquiau, Audrey; Achaintre, David; Scalbert, Augustin; Ferrari, Pietro; Romieu, Isabelle; Onland-Moret, N. Charlotte; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Olsen, Anja; Tjønneland, Anne; Fournier, Agnès; Rothwell, Joseph A.; Severi, Gianluca; Kühn, Tilman; Fortner, Renée Turzanski; Boeing, Heiner; Trichopoulou, Antonia; Karakatsani, Anna; Martimianaki, Georgia; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Vineis, Paolo; Panico, Salvatore; van Gils, Carla H.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Skeie, Guri; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Amiano, Pilar; Huerta, José María; Ardanaz, Eva; Schmidt, Julie A.; Travis, Ruth C.; Riboli, Elio; Tsilidis, Konstantinos K.; Christakoudi, Sofia; Gunter, Mark J.; Rinaldi, Sabina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-24)
      <i>Background</i> - Metabolomics is a promising molecular tool to identify novel etiologic pathways leading to cancer. Using a targeted approach, we prospectively investigated the associations between metabolite concentrations in plasma and breast cancer risk.<p> <p><i>Methods</i> - A nested case-control study was established within the European Prospective Investigation into Cancer cohort, which ...
    • Prospective analysis of circulating metabolites and endometrial cancer risk 

      Dossus, Laure; Kouloura, Eirini; Biessy, Carine; Viallon, Vivian; Siskos, Alexandros P.; Dimou, Niki; Rinaldi, Sabina; Merritt, Melissa A.; Allen, Naomi E.; Fortner, Renée T.; Kaaks, Rudolf; Weiderpass, Elisabete; Gram, Inger Torhild; Rothwell, Joseph A.; Lécuyer, Lucie; Severi, Gianluca; Schulze, Matthias B.; Nøst, Therese Haugdahl; Crous-Bou, Marta; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Schmidt, Julie A.; Palli, Domenico; Agnoli, Claudia; Tumino, Rosario; Sacerdote, Carlotta; Mattiello, Amalia; Vermeulen, Roel; Heath, Alicia K.; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Travis, Ruth C.; Gunter, Marc J.; Keun, Hector C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Background. Endometrial cancer is strongly associated with obesity and dysregulation of metabolic factors such as estrogen and insulin signaling are causal risk factors for this malignancy. To identify additional novel metabolic pathways associated with endometrial cancer we performed metabolomic analyses on pre-diagnostic plasma samples from 853 case-control pairs from the European Prospective ...
    • A prospective cohort study on risk factors of musculoskeletal complaints (pain and/or stiffness) in a general population. The Tromsø study 

      Andorsen, Ole Fredrik; Ahmed, Luai A.; Emaus, Nina; Klouman, Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-20)
      Background: Female gender has been associated with musculoskeletal complaints (MSCs), but there are limited studies on how other factors may influence women and men differently. The aim of this prospective cohort study was to explore possible predictors of MSCs in women and men free of MSCs at baseline. <br>Methods: The present study included participants from the population-based Tromsø study, with ...
    • A Prospective Diet-Wide Association Study for Risk of Colorectal Cancer in EPIC 

      Papadimitriou, Nikos; Bouras, Emmanouil; van den Brandt, Piet A.; Muller, David C.; Papadopoulou, Areti; Heath, Alicia K.; Critselis, Elena; Gunter, Marc; Vineis, Paolo; Ferrari, Pietro; Weiderpass, Elisabete; Boeing, Heiner; Bastide, Nadia; Merritt, Melissa A.; Lopez, David S.; Bergmann, Manuela M.; Perez-Cornago, Aurora; Schulze, Matthias; Skeie, Guri; Srour, Bernard; Eriksen, Anne Kirstine; Boden, Stina; Johansson, Ingegerd; Nøst, Therese Haugdahl; Lukic, Marko; Ricceri, Fulvio; Ericson, Ulrika; Huerta, José-Maria; Dahm, Christina C.; Agnoli, Claudia; Amiano, Pilar; Tjønneland, Anne; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Ardanaz, Eva; Berntsson, Jonna; Sánchez, Maria-Jose; Tumino, Rosario; Panico, Salvatore; Katzke, Verena; Jakszyn, Paula; Masala, Giovanna; Derksen, Jeroen W.G.; Quirós, J. Ramón; Severi, Gianluca; Cross, Amanda J.; Riboli, Ellio; Tzoulaki, Ioanna; Tsilidis, Konstantinos K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-24)
      Background & Aims - Evidence regarding the association of dietary exposures with colorectal cancer (CRC) risk is not consistent with a few exceptions. Therefore, we conducted a diet-wide association study (DWAS) in the European Prospective Investigation into Cancer and Nutrition (EPIC) to evaluate the associations between several dietary exposures with CRC risk.<p> <p>Methods - The association ...
    • Prospective evaluation of 92 serum protein biomarkers for early detection of ovarian cancer 

      Mukama, Trasias; Fortner, Renée Turzanski; Katzke, Verena; Hynes, Lucas Cory; Petrera, Agnese; Hauck, Stefanie M.; Johnson, Theron; Schulze, Matthias; Schiborn, Catarina; Rostgaard-Hansen, Agnetha Linn; Tjønneland, Anne; Overvad, Kim; Pérez, María José Sánchez; Crous-Bou, Marta; Chirlaque, María-Dolores; Amiano, Pilar; Ardanaz, Eva; Watts, Eleanor L.; Travis, Ruth C.; Sacerdote, Carlotta; Grioni, Sara; Masala, Giovanna; Signoriello, Simona; Tumino, Rosario; Gram, Inger Torhild; Sandanger, Torkjel M; Sartor, Hanna; Lundin, Eva; Idahl, Annika; Heath, Alicia K.; Dossus, Laure; Weiderpass, Elisabete; Kaaks, Rudolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-01-14)
      BACKGROUND: CA125 is the best available yet insufficiently sensitive biomarker for early detection of ovarian cancer. There is a need to identify novel biomarkers, which individually or in combination with CA125 can achieve adequate sensitivity and specificity for the detection of earlier-stage ovarian cancer.<p> <p>METHODS: In the European Prospective Investigation into Cancer and Nutrition ...