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dc.contributor.authorStorm, Benjamin Stage
dc.contributor.authorChristiansen, Dorte
dc.contributor.authorDybwik, Knut
dc.contributor.authorMollnes, Tom Eirik
dc.contributor.authorNielsen, Erik Waage
dc.date.accessioned2018-10-03T08:01:49Z
dc.date.available2018-10-03T08:01:49Z
dc.date.issued2017-10-01
dc.description.abstract<p><i>Introduction</i>: Venous air embolism (VAE) may arise during surgical procedures. VAE might be complicated with a systemic inflammatory response, disseminated intervascular coagulation, multi-organ failure and cardiovascular collapse. During a short time-span, three patients at our institution developed signs of VAE in conjunction with gynecological surgery. One died, one developed severe cerebral infarctions and one developed myocardial infarction.<p> <p>Previously, air embolisms have been shown to trigger complement C3 and C5 activation in plasma. We have examined in vitro in human whole blood and in vivo in a porcine model, how air triggers inflammation and activation of complement and coagulation and their cross-talk.</p>en_US
dc.descriptionAccepted manuscript version, licensed <a href=http://creativecommons.org/licenses/by-nc-nd/4.0/> CC BY-NC-ND 4.0. </a> Source at: <a href=https://doi.org/10.1016/j.molimm.2017.06.196> https://doi.org/10.1016/j.molimm.2017.06.196 </a>en_US
dc.identifier.citationStorm, B. S. (2017). Gas embolism during surgery. A complement mediated condition?. Molecular Immunology, 2017(89), 193-193. https://doi.org/10.1016/j.molimm.2017.06.196en_US
dc.identifier.cristinIDFRIDAID 1572062
dc.identifier.doihttps://doi.org/10.1016/j.molimm.2017.06.196
dc.identifier.issn0161-5890
dc.identifier.issn1872-9142
dc.identifier.urihttps://hdl.handle.net/10037/13899
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.journalMolecular Immunology
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S0161589017303693
dc.rights.accessRightsopenAccessen_US
dc.subjectVDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Medisinsk immunologi: 716en_US
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710::Medical immunology: 716en_US
dc.titleGas embolism during surgery. A complement mediated condition?en_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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