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norskDoktorgradsavhandlinger (NT-fak): Nye registreringer
Viser treff 261-280 av 305
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Synthesis of a novel class of antitubercular peptidomimetics based on β-aminoboronates.
(Doctoral thesis; Doktorgradsavhandling, 2012-11-16)The unique properties of antimicrobial peptides have attracted the attention of chemists since the 1970’s. This class of compounds provides additional tools in the treatment of infections and the work described in this thesis was therefore focused on the synthesis of short peptidomimetics on the basis of modified amino acids and evaluation of their antimicrobial activity. The compounds of choice ... -
Synthetic aperture ultrasound imaging with application to interior pipe inspection
(Doctoral thesis; Doktorgradsavhandling, 2012-09-07)This thesis is concerned with synthetic aperture focusing of ultrasonic pulse-echo measurements, with application to multilayered media and cylindrical structures. The work is motivated by the need for accurate methods for non-destructive testing of pipelines, particularly water distribution pipelines. By improving the lateral resolution in ultrasonic measurements, the synthetic aperture algorithms ... -
A multidisciplinary subsurface analysis of mud volcanoes and salt diapirs in European Seas
(Doctoral thesis; Doktorgradsavhandling, 2012-09-13) -
Benthic foraminifera in an Arctic fjord : recent distribution and fauna of the last two millennia
(Doctoral thesis; Doktorgradsavhandling, 2012-09-13)The main objective of the PhD study was to improve the knowledge about the ecology of the benthic foraminiferal faunas thus increasing the precision of benthic foraminifera as indicators for modern and past Arctic fjord and shelf environments. The investigation of living (stained) benthic foraminifera assemblages in Kongsfjorden (western Svalbard) was performed on inter-annual and seasonal time ... -
Scale-space methodology applied to spectral feature detection, multinormality testing and the k-sample problem, and wavelet variance analysis
(Doctoral thesis; Doktorgradsavhandling, 2012-03-23)The number of scale-space statistical algorithms has been greatly increased over the last 15 years. The concept originated from computer vision, introduced in Lindeberg (1994). The seminal paper by Chaudhuri and Marron (1999) brought the scale-space concept into smoothing of curves and kernel density estimation through the SiZer tool. By using all relevant smoothing bandwidths, i.e., the scale part, ... -
Particle precipitation : effects on selected ionospheric phenomena
(Doctoral thesis; Doktorgradsavhandling, 2009-11-26)The motivation behind this thesis has been to study particle precipitation from the Sun into the Earth’s upper atmosphere and its effects on selected ionospheric phenomena. Particles from the solar wind can enter the Earth's magnetosphere through magnetic merging, either at the sub-solar point, or at higher latitudes, depending on the configuration of the interplanetary magnetic field. This interaction ... -
Arctic Ocean warmings from the last glaciation to the present : implementing and assessing the reliability of planktic foraminiferal paleoreconstructions
(Doctoral thesis; Doktorgradsavhandling, 2012-05-11)The aim of the PhD study was to use planktic foraminifera to elucidate paleoceanographic variability and the preservation state of calcium carbonate in the eastern Fram Strait throughout the last 30,000 years. Sediment cores were studied using a multiproxy approach which included analyzing planktic and benthic foraminiferal fauna distribution patterns, measurements of stable isotopes (δ18O, δ13C), ... -
Protein kinase selectivity mechanisms and structure assisted drug discovery
(Doctoral thesis; Doktorgradsavhandling, 2012-02-24)Protein fosforylering er en av de viktigste intracellulære signaltransduksjonsmekanismer i eukaryote og er involvert i nesten alle cellulære prosesser. Avvikende kinase aktivitet kan forårsake mange alvorlige sykdommer som diabetes og kreft. Bruk av små molekyler for å modulere protein kinase aktivitet er nå en validert metode for behandling av slike sykdommer. Men imidlertid har kliniske studier ... -
Palaeoenvironment of the Barents Sea during the last deglaciation and Holocene : processes and timing
(Doctoral thesis; Doktorgradsavhandling, 2012-03-01)The scope of this PhD thesis is twofold: Firstly, processes, patterns and timing of the last deglaciation in the Barents Sea are reconstructed and secondly, depositional conditions on the Barents shelf during Holocene are elucidated. This cumulative PhD thesis encompasses an introductory part and five papers - three as first-author and two as co-author. Three papers are focused on the most prominent ... -
Design and Evaluation of a Medical Microwave Radiometer for Observing Temperature Gradients Subcutaneously in the Human Body
(Doctoral thesis; Doktorgradsavhandling, 2012-02-01)The topic covered in this thesis is medical temperature measurement of subcutaneous parts of human tissue with use of microwave radiometry. Radiometry is a completely non-invasive, non-toxic and relatively inexpensive sensing modality. The radiometric technique is based on the measurement of electromagnetic noise power emitted by lossy materials. The method has explicit low investment costs and ... -
Cogset : A High-Performance MapReduce Engine
(Doctoral thesis; Doktorgradsavhandling, 2012-01-30)MapReduce has become a widely employed programming model for large-scale data-intensive computations. Traditional MapReduce engines employ dynamic routing of data as a core mechanism for fault tolerance and load balancing. An alternative mechanism is static routing, which reduces the need to store temporary copies of intermediate data, but requires a tighter coupling between the components for ... -
The Dayside Open/Closed Field line Boundary -Ground-based optical determination and examination
(Doctoral thesis; Doktorgradsavhandling, 2011-12-20)The Open/Closed eld line Boundary (OCB) is the most important boundary in the magnetospheric system. On the dayside, the equatorward edge of the 6300 Å[OI] cusp aurora can be used as a proxy for the OCB. This work, which is a dissertation for the degree of philosophiæ Doctor consists of three scienti c papers focusing on the latitude of the optical cusp OCB and one paper focusing on polar cap patch ... -
Automatic Inspection of Cod (Gadus Morhua L.) Fillets by Hyperspectral Imaging
(Doctoral thesis; Doktorgradsavhandling, 2011-11-11)The manual trimming and inspection of cod fillets by candling, is considered the bottleneck of cod fillet processing. The operation is both labour intensive and expensive, reported to account for as much as 50 % of the cost with cod fillet production. Due to the high labour costs in Norway, it is of great interest for the industry to optimize this process. In this work a hyperspectral imaging ... -
Interactive Visualization on High-Resolution Tiled Display Walls with Network Accessible Compute- and Display-Resources
(Doctoral thesis; Doktorgradsavhandling, 2011-09-26)The vast volume of scientific data produced today requires tools that can enable scientists to explore large amounts of data to extract meaningful information. One such tool is interactive visualization. The amount of data that can be simultaneously visualized on a computer display is proportional to the display’s resolution. While computer systems in general have seen a remarkable increase in ... -
Practical Fault-Tolerance for Mobile Agents
(Doctoral thesis; Doktorgradsavhandling, 2011-10-18)The amount of computational resources available on the Internet is increasing. Effectively using these resources for distributed computations is challenging. An infrastructure called computational grids provides tools for structuring and deploying large-scale distributed computations on the Internet. One of the key problems in computational grids is managing the available computational resources; ... -
U-Pb geochronology of crustal evolution and orogeny Contributions from Caledonide Spitsbergen and the Precambrian West Troms Basement Complex, North Norway
(Doctoral thesis; Doktorgradsavhandling, 2011-09-23) -
Minor element abundances in the corona and solar wind
(Doctoral thesis; Doktorgradsavhandling, 2011-10-21)Using a time-dependent numerical model that spans the chromosphere, corona and solar wind, abundance variations resulting from gravitational settling in the chromosphere and corona have been studied. \noindent Gravitational settling in the chromosphere may lead to a depletion in the abundances of minor elements in the solar wind relative to the photosphere. The observed overabundance (relative ... -
Theoretical studies of natural and magnetic circular dichroism
(Doctoral thesis; Doktorgradsavhandling, 2011-06-23)This dissertation presents theoretical studies mainly of natural and magnetic circular dichroism spectra. For magnetic circular dichroism, the importance of electron correlation effects, here included at the density-functional functional level of theory, and solvent effects are discussed, both being shown to have significant impact on the final spectra. In addition, a unified approach for calculating ... -
Theoretical studies of natural and electromagnetically induced birefringences
(Doctoral thesis; Doktorgradsavhandling, 2011-06-01) -
Model based Statistics for Protein Sequence Families
(Doctoral thesis; Doktorgradsavhandling, 2011-07-01)
