<p>You cannot imagine powering through the day without your favorite beverage being on your desk all the time. Have you ever wondered what the consequences might be? </p> <p>It seems that even before you have opened your eyes, there’s already a kettle on the stove or the coffee machine is purring. On the way to work, you have another cup to go from the nearby coffee chop. Long meetings demand ...

<p>Autolog hematopoietisk stamcelletransplantasjon (HSCT) er en behandlingsform som er foreslått for en liten gruppe pasienter med attakkpreget multippel sklerose der tilgjengelig medikamentell behandling har begrenset effekt eller gir store bivirkninger. I denne metodevurderingen har vi oppsummert og vurdert forskning om effekt, sikkerhet, økonomiske evalueringer og etiske problemstillinger knyttet ...

<p><i>Objective</i>: This study aimed to assess and compare the distribution of cardiovascular risk factors and the estimated 10-year risk of fatal or non-fatal acute myocardial infarction (AMI) or cerebral stroke (CS) among the Sami and non-Sami populations of Northern Norway.</p> <p><i>Methods</i>: The SAMINOR 2 Clinical Survey is a cross-sectional survey conducted in 10 municipalities in the ...

Background: <br>The joint effect of atherosclerosis and CRP (C-reactive protein) on risk of ischemic stroke (IS) and myocardial infarction (MI) has been sparsely studied. The aim of this study was to explore whether CRP mediates the risk of events in subjects with prevalent carotid plaque, examine synergism, and test whether CRP and carotid plaque add to risk prediction beyond traditional risk ...

<p><i>Background</i>: Oral health (OH) is poor among young adults in Russia, but there is little information on OH-related quality of life (OHRQoL) in this population. We investigated how socio-demographic factors, self-reported OH characteristics, oral health behaviour, and clinically-assessed OH are related to OHRQoL in medical and dental students in North-West Russia.</p> <p><i>Methods</i>: ...

Norwegians are the second highest consumers of coffee in the world. Lately, several studies have suggested that beneficial health effects are associated with coffee consumption. By analyzing whole-blood derived, microarray based mRNA gene expression data from 958 cancer-free women from the Norwegian Women and Cancer Post-Genome Cohort, we assessed the potential associations between coffee consumption ...

<p><i>Background</i>: The relationship between the various items in an HRQoL instrument is a key aspect of interpreting and understanding preference weights. The aims of this paper were i) to use theoretical models of HRQoL to develop a conceptual framework for causal and effect relationships among the five dimensions of the EQ-5D instrument, and ii) to empirically test this framework.</p> ...

<p><i>Purpose</i>: Early age at menarche (AAM) has been associated with increased mortality and morbidity, including premature death from all causes, breast cancer and cardiovascular diseases. The aim of this study was to examine the association between AAM and all-cause mortality.</p> <p><i>Subjects and methods</i>: A total of 12,409 women aged 25–94 years who took part in the fourth Tromsø Study ...

Regularly conducted population cohort studies contribute important new knowledge to medical research. A high participation rate is required in these types of studies in order to claim representativeness and validity of study results. Participation rates are declining worldwide, and re-searchers are challenged to develop new data collection strategies and tools to motivate people to participate. The ...

The main objectives of this study were to investigate the association between childhood violence and psychological distress and post-traumatic stress symptoms (PTS) among Sami and non-Sami adults, and to explore a possible mediating effect of childhood violence on any ethnic differences in mental health. This study is part of a larger questionnaire survey on health and living conditions in Mid- and ...