English
norskBlar i tittel Det helsevitenskapelige fakultet
Viser treff 4676-4695 av 10125
-
Improving response rate and quality of survey data with a scratch lottery ticket incentive
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)The quality of data collected in survey research is usually indicated by the response rate; the representativeness of the sample, and; the rate of completed questions (item-response). In attempting to improve a generally declining response rate in surveys considerable efforts are being made through follow-up mailings and various types of incentives. This study examines effects of including a scratch ... -
Improving the Applicability of AI for Psychiatric Applications through Human-in-the-loop Methodologies
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-26)Objectives: Machine learning (ML) and natural language processing have great potential to improve effciency and accuracy in diagnosis, treatment recommendations, predictive interventions, and scarce resource allocation within psychiatry. Researchers often conceptualize such an approach as operating in isolation without much need for human involvement, yet it remains crucial to harness human-inthe-loop ... -
Improving the spirit – increasing the chances of survival : results of multiprofessional training of medical teams in Iraq and Norway
(Doctoral thesis; Doktorgradsavhandling, 2008-05-30)This work is a synthesis of experiences gained during ten years of helping healthcare providers improve their service to victims of injury and acute disease. This work is based on my participation in two programs: The Trauma Care Foundation’s Mine Injury Management Program in Kurdistan, northern Iraq, and the BEST Foundation: Better & Systematic Trauma Care’s trauma team training program in Norwegian ... -
Improving translational research in sex-specific effects of comorbidities and risk factors in ischaemic heart disease and cardioprotection: Position paper and recommendations of the ESC Working Group on Cellular Biology of the Heart
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-02)Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and morbidity in both men and women. Sex, however, affects several aspects of IHD, including pathophysiology, incidence, clinical presentation, diagnosis as well as treatment and outcome. Several diseases or risk factors frequently associated with IHD can modify cellular signalling cascades, thus affecting ischaemia/reperfusion ... -
Improving validity of the trail making test with alphabet support
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-27)The Trail Making Test (TMT) is commonly used worldwide to evaluate cognitive decline and car driving ability. However, it has received critique for its dependence on the Latin alphabet and thus, the risk of misclassifying some participants. Alphabet support potentially increases test validity by avoiding misclassification of executive dysfunction in participants with dyslexia and those with insufficient ... -
Improvised use of a digital tool for social interaction in a Norwegian care facility during the COVID-19 pandemic: an exploratory study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-01)Background: Digital tools for social communication have been deployed in care facilities during the COVID-19 pandemic to facilitate social connectedness between older people and their next of kin in a safe manner. This study explores how and why health care professionals facilitate the ad hoc and prompt use of a technology for social communication, known as KOMP, in care facilities in western ... -
In Brief Neuropsychological Assessment, Amnestic Mild Cognitive Impairment (MCI) Is associated with Cerebrospinal Fluid Biomarkers for Cognitive Decline in Contrast to the Prevailing NIA-AA MCI Criterion
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-22)<i>Background:</i> In the care of persons with cognitive problems, it is important to use a valid mild cognitive impairment (MCI) criterion that discriminates well between normal and pathological aging.<p> <p><i>Objective:</i> To find the brief neuropsychological screening criterion that best correlates with cerebrospinal fluid (CSF) biomarkers for cognitive decline and dementia in persons ... -
’In gille huma’. De tause rommene i samtalen : samiske fortellinger om kreft
(Master thesis; Mastergradsoppgave, 2006-11-11)Dette mastergradsarbeidet handler om hvordan man kan forstå det å ha kreftsykdom ut fra hvordan sykdommen snakkes, eller ikke snakkes om i samiske samfunn. Det er i dagens kreftomsorg et sterkt fokus på å hjelpe de som rammes av kreft til å mestre krisen dette kan oppleves som. Samtale; det å snakke om og sette ord på følelser, tanker og reaksjoner anses som den viktigste metoden i krisebearbeidingen. ... -
In Home we trust. An ethnographic study of mental health and the use of traditional medicine in a North Norwegian community
(Doctoral thesis; Doktorgradsavhandling, 2019-05-24)Traditional healing practices used when faced with illness or crisis, exist in many North Norwegian communities. Northern Troms has a historical multi-ethnicity of Sami, Kven and Norwegian. The notion of culture appears ambivalent and ambiguous, particularly concerning the Sami identity, but cultural diversity is nevertheless manifested through the use of traditional healing practices such as reading. ... -
In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies
(Journal article; Tidsskriftartikkel, 2009) -
In need of percutaneous coronary intervention in an arctic setting– patients’ experience of safety and quality of care: a qualitative study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-29)Patients with coronary heart disease need timely treatment for survival and optimum prognosis. There is limited research exploring patients’ experience regarding distance to percutaneous coronary intervention. The aim was to explore patients’ experiences of aspects contributing to safety and quality of care regarding health services following percutaneous coronary intervention in Northern Norway. A ... -
In plastico: laboratory material newness affects growth and reproduction of Daphnia magna reared in 50-ml polypropylene tubes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-20)Plastic laboratory materials are found to affect vital parameters of the waterflea Daphnia magna. The main responsible factor is defined as “newness” of the materials. Juvenile D. magna were raised individually in; a) new laboratory-standard 50 ml polypropylene tubes, and; b) identical tubes which had been washed and aerated for several weeks. Newness had significant effects on growth and fecundity ... -
In search of a common currency: A comparison of seven EQ‐5D‐5L value sets
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-24)The recently published EQ‐5D‐5L value sets from Canada, England, Japan, Korea, the Netherlands, Spain, and Uruguay are compared with an aim to identify any similarities in preference pattern. We identify some striking similarities for Canada, England, the Netherlands, and Spain in terms of (a) the relative importance of the 5 dimensions; (b) the relative utility decrements across the 5 levels; and ... -
In Silico Methods for the Discovery of Orthosteric GABAB Receptor Compounds
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-07)The GABA<sub>B</sub> receptor (GABA<sub>B</sub>-R) is a heterodimeric class C G protein-coupled receptor comprised of the GABA<sub>B1a/b</sub> and GABA<sub>B2</sub> subunits. The endogenous orthosteric agonist γ-amino-butyric acid (GABA) binds within the extracellular Venus flytrap (VFT) domain of the GABA<sub>B1a/b</sub> subunit. The receptor is associated with numerous neurological and ... -
In silico screening for GAT-3 inhibitors
(Master thesis; Mastergradsoppgave, 2017-05-15)ϒ-aminobutyric acid (GABA) is the main inhibitory neurotransmitter of the central nervous system (CNS). GABA exert is function by binding to three different receptor subtypes, the GABAA, GABAB and GABAC receptor. The GABA level in different brain regions are regulated by four GABA transporters (GATs); GAT-1, GAT-2, GAT-3 and BGT-1. GAT-3 is located in glial cells that is controlling GABA function ... -
In silico site-directed mutagenesis of the Daphnia magna ecdysone receptor identifies critical amino acids for species-specific and inter-species differences in agonist binding
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-04)Molting is an essential process in the life cycle of arthropods and is regulated by complex neuroendocrine pathways where activation of the ecdysone receptor (EcR) plays a major role. The EcR forms a non-covalent heterodimer with the ultraspiracle protein (USP) when activated by endogenous ecdysteroids, but can also be activated by several insecticides and other environmental chemicals. Environmental ... -
In situ simulation training strengthened bachelor of nursing students’ experienced learning and development process– a qualitative study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-15)Background In advanced clinical learning labs on campus, high-fidelity simulation has become an essential educational approach in the Bachelor of Nursing Education programme. However, simulation while in clinical placement, in situ, is rarely used in Bachelor of Nursing Education. The aim of the present study was to explore how in situ simulation training at a surgical hospital ward, according ... -
In the Blink of an Eye: Investigating the Role of Awareness in Fear Responding by Measuring the Latency of Startle Potentiation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2012)The latency of startle reflex potentiation may shed light on the aware and unaware processes underlying associative learning, especially associative fear learning. We review research suggesting that single-cue delay classical conditioning is independent of awareness of the contingency between the conditioned stimulus (CS) and the unconditioned stimulus (US). Moreover, we discuss research that argues ... -
In utero exposure to endocrine disrupting chemicals, micro-RNA profiles, and fetal growth: a pilot study protocol
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-05)<i>Background</i>: The developing fetus is particularly vulnerable to the effects of endocrine disrupting chemicals (EDCs). Molecular fingerprints of EDCs can be identified via microRNA (miRNA) expression profiles and may be etiologically implicated in the developmental origin of disease (DOHaD).<p> <p><i>Methods/design</i>: This pilot study includes pregnant women at high risk (smoking at ... -
In Vitro and in Silico Competitive Binding of Brominated Polyphenyl Ether Contaminants with Human and Gull Thyroid Hormone Transport Proteins
(Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-28)Tetradecabromo-1,4-diphenoxybenzene (TeDB-DiPhOBz) is a highly brominated additive flame retardant (FR). Debrominated photodegradates of TeDBDiPhOBz are hydroxylated <i>in vitro</i> in liver microsomal assays based on herring gulls (<i>Larus argentatus</i>), including one metabolite identified as 4<i>″</i>-OH-2,2<i>′</i>,2<i>″</i>,4-tetrabromo-DiPhOBz. Chemically related methoxylated tetra- ...
