Viser treff 4941-4960 av 10152

    • Interactive disease maps for the snow agent system 

      Dhakal, Sanjaya Babu (Master thesis; Mastergradsoppgave, 2009-06-03)
      The aim of this research was to develop an interactive disease map framework and integrate Silverlight map support for the research project developing the Snow Agent System. The interactive disease map can be used for visualizing information on the map during disease outbreak situations. An engineering approach was used for system design, development and testing. Three different inputs, Microsoft ...
    • Interaksjonen mellom glukokortikoidreseptoren og Pax6 under genregulering i sebrafiskembryo og mammalske celler i kultur 

      Skaue, Lillann Wilsgård (Master thesis; Mastergradsoppgave, 2013-05-20)
      Det er kjent at glukokortikoidreseptoren (GR) og Pax6 som begge er transkripsjonsfaktorer og blant annet er viktig for normal embryoutvikling, har noen felles målgener blant matriks metalloproteinasene (MMP.) MMPer sørger for remodellering av ekstracellulær matriks (ECM) og er svært viktige under embryogenesen. Fra før av er det kjent at både GR og Pax6 regulerer uttrykket MMP2 og MMP9. I ...
    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) – a randomized controlled trial 

      Johansen, Jeanette Schultz; Halvorsen, Kjell H.; Svendsen, Kristian; Havnes, Kjerstin; Robinson, Eirin Guldsten; Wetting, Hilde Ljones; Haustreis, Stine; Småbrekke, Lars; Kamycheva, Elena; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      <b><p>Background</b> Suboptimal medication use contributes to a substantial proportion of hospitalizations and emergency department visits in older adults. We designed a clinical pharmacist intervention to optimize medication therapy in older hospitalized patients. Based on the integrated medicine management (IMM) model, the 5-step IMMENSE intervention comprise medication reconciliation, medication ...
    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial 

      Johansen, Jeanette Schultz; Havnes, Kjerstin; Halvorsen, Kjell H.; Haustreis, Stine-Mari; Skaue, Lillann Wilsgård; Kamycheva, Elena; Mathiesen, Liv; Viktil, Kirsten Kilvik; Granås, Anne Gerd; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-23)
      <p><i>Introduction:</i> Drug-related problems (DRPs) are common in the elderly, leading to suboptimal therapy, hospitalisations and increased mortality. The integrated medicines management (IMM) model is a multifactorial interdisciplinary methodology aiming to optimise individual medication therapy throughout the hospital stay. IMM has been shown to reduce readmissions and drug-related hospital ...
    • Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (The IMMENSE study) – a randomized controlled trial 

      Johansen, Jeanette Schultz; Halvorsen, Kjell H.; Svendsen, Kristian; Havnes, Kjerstin; Robinson, Eirin Guldsten; Ljones Wetting, Hilde; Haustreis, Stine; Småbrekke, Lars; Kamycheva, Elena; Garcia, Beate Hennie (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)
      Background - Suboptimal medication use contributes to a substantial proportion of hospitalizations and emergency department visits in older adults. We designed a clinical pharmacist intervention to optimize medication therapy in older hospitalized patients. Based on the integrated medicine management (IMM) model, the 5-step IMMENSE intervention comprise medication reconciliation, medication review, ...
    • Interkommunal legevaktssamarbeid kan styrke pasientsikkerheten 

      Pedersen, Anita Monsen (Master thesis; Mastergradsoppgave, 2013-05-13)
      Denne oppgaven tar primært for seg to legevakter i distriktet med store avstander, der man ser på problemstillingen rundt kommunenes ofte anstrengte økonomi, som reiser spørsmål om interkommunale legevaktsordninger. Oppgaven belyser i stor grad pasientsikkerheten slik situasjonen er i dag, og om denne vil endres ved et legevaktssamarbeid. For å besvare problemstillingen er det utført et ...
    • Interlaboratory evaluation of a digital holographic microscopy–based assay for label-free in vitro cytotoxicity testing of polymeric nanocarriers 

      Marzi, Anne; Eder, Kai Moritz; Barroso, Álvaro; Wågbø, Ane Marit; Mørch, Ýrr Asbjørg; Hatletveit, Anne Rein; Visnes, Torkild; Schmid, Ruth Baumberger; Klinkenberg, Geir; Kemper, Björn; Schnekenburger, Jürgen (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-08)
      State-of-the-art in vitro test systems for nanomaterial toxicity assessment are based on dyes and several staining steps which can be affected by nanomaterial interference. Digital holographic microscopy (DHM), an interferometry-based variant of quantitative phase imaging (QPI), facilitates reliable proliferation quantification of native cell populations and the extraction of morphological features ...
    • Interleukin 33: a locally induced alarmin in the colonic mucosa of ulcerative colitis 

      Gundersen, Mona Dixon (Doctoral thesis; Doktorgradsavhandling, 2022-09-27)
      Ulcerative colitis (UC) is a chronic inflammatory bowel disease involving the mucosal lining of the large bowel (colon and rectum). Common symptoms include bouts of diarrhoea, rectal bleeding and abdominal pain. The pathogenesis of UC is complex and multifactorial. This thesis investigated interleukin 33 (IL-33), an alarmin of the innate immune system. IL-33 is of interest as it is found to be ...
    • Interleukin-1β as emerging therapeutic target in hematological malignancies and potentially in their complications 

      Arranz, Lorena; Arriero Sanchez, Maria Del Mar; Villatoro, Alicia (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-03)
      Interleukin-1β (IL-1β) is a pleiotropic cytokine that exerts multiple roles in both physiological and pathological conditions. It is produced by different cell subsets, and drives a wide range of inflammatory responses in numerous target cells. Enhanced IL-1β signaling is a common event in patients of hematological malignancies. Recent body of evidence obtained in preclinical models shows the ...
    • Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction 

      Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål; Damås, Jan Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-29)
      <p><i>Aim</i>: To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network in patients with acute non-ST-elevation myocardial infarction (NSTEMI).</p> <p><i>Methods</i>: 117 patients with acute NSTEMI were randomised to an intravenous infusion of 280 mg tocilizumab or placebo prior to coronary angiography. Blood samples were obtained at baseline, at 6 consecutive ...
    • Intermittent Absence of Control during Reinforcement Learning Interferes with Pavlovian Bias in Action Selection 

      Csifcsak, Gabor; Melsæter, Eirik; Mittner, Matthias (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-02)
      The ability to control the occurrence of rewarding and punishing events is crucial for our well-being. Two ways to optimize performance are to follow heuristics like Pavlovian biases to approach reward and avoid loss or to rely more on slowly accumulated stimulus–action associations. Although reduced control over outcomes has been linked to suboptimal decision-making in clinical conditions associated ...
    • Intern kvalitetsundersøkelse av rutiner og forhold rundt elektiv elektrokonvertering hos pasienter på hjertemedisinsk avdeling, Universitetssykehuset Tromsø 

      Dons, Tine Nilsen (Master thesis; Mastergradsoppgave, 2009-09-15)
      Formålet med oppgaven er å kunne si noe om: 1) Rutinene rundt den elektive elektrokonverteringen ved Universitetssykehuset Nord-Norge (UNN) Tromsø i forhold til retningslinjene laget av American College of Cardiology (ACC), American Heart Association (AHA) og European Society of Cardiology (ESC). 2) Resultatene av elektiv elektrokonvertering på hjertemedisinsk avdeling, UNN Tromsø. 3) Undersøke ...
    • Internalizing problems and attentional control: Effects on cardiac autonomic responses after the induction of negative affect 

      Andersen, Tonje Grønning; Fiskum, Charlotte; Aslaksen, Per M; Flaten, Magne Arve; Jacobsen, Karl Henry (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      Individuals with internalizing problems differ in levels of attentional control (AC), and this heterogeneity could be associated with differences in autonomic arousal. The present study investigated whether AC moderated the effect of internalizing problems on self-reported experience and autonomic nervous system (ANS) responses after the induction of negative affect. Children aged 9–13 years were ...
    • The International Collaboration on Complementary Therapy Resources (ICCR) : working together to improve online CAM information 

      Pilkington, Karen; Gamst, are; Liu, Irene; Ostermann, Thomas; Pinto, Dimitry; Richardon, Janet (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Use of the Internet to find health information is increasing dramatically but the quality of information, particularly on complementary and alternative medicine (CAM) is variable. The International Collaboration on Complementary Therapy Resources (ICCR) involves collaboration between the national CAM information centers in Australia, Denmark, Norway, the United Kingdom, and the United States, and a ...
    • International perception of lung sounds: a comparison of classification across some European borders 

      Aviles Solis, Juan Carlos; Vanbelle, Sophie; Halvorsen, Peder Andreas; Francis, Nick; Cals, Jochem W L; Andreeva, Elena A; Marques, Alda; Piirila, Paivi; Pasterkamp, Hans; Melbye, Hasse (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-18)
      Introduction: Lung auscultation is helpful in the diagnosis of lung and heart diseases; however, the diagnostic value of lung sounds may be questioned due to interobserver variation. This situation may also impair clinical research in this area to generate evidence-based knowledge about the role that chest auscultation has in a modern clinical setting. The recording and visual display of lung sounds ...
    • International pooled study on diet and bladder cancer: The bladder cancer, epidemiology and nutritional determinants (BLEND) study: Design and baseline characteristics 

      Goossens, Maria E.; Isa, Fatima; Brinkman, Maree; Mak, David; Reulen, Raoul; Wesselius, Anke; Benhamou, Simone; Bosetti, Cristina; Bueno-de-Mesquita, H. Bas; Carta, Angela; Allam, Md Farouk; Golka, Klaus; Grant, Eric J.; Jiang, Xuejuan; Johnson, Kenneth C.; Karagas, Margaret R.; Kellen, Eliane; La Vecchia, Carlo; Lu, Chih-Ming; Marshall, James; Moysich, Kirsten; Pohlabeln, Hermann; Porru, Stefano; Steineck, Gunnar; Stern, Marianne C.; Tang, Li; Taylor, Jack A.; van den Brandt, Piet; Villeneuve, Paul J.; Wakai, Kenji; Weiderpass, Elisabete; White, Emily; Wolk, Alicja; Zhang, Zuo-Feng; Buntinx, Frank; Zeegers, Maurice P. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-06)
      Background: In 2012, more than 400,000 urinary bladder cancer cases occurred worldwide, making it the 7th most common type of cancer. Although many previous studies focused on the relationship between diet and bladder cancer, the evidence related to specific food items or nutrients that could be involved in the development of bladder cancer remains inconclusive. Dietary components can either be, ...
    • Internet Use for Obtaining Medicine Information: Cross-sectional Survey 

      Bergmo, Trine Strand; Sandsdalen, Vilde; Manskow, Unn Sollid; Småbrekke, Lars; Waaseth, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-22)
      Background: The internet is increasingly being used as a source of medicine-related information. People want information to facilitate decision-making and self-management, and they tend to prefer the internet for ease of access. However, it is widely acknowledged that the quality of web-based information varies. Poor interpretation of medicine information can lead to anxiety and poor adherence to ...
    • Internet-based cognitive behavior therapy for depression: Effectiveness and patient experiences 

      Lillevoll, Kjersti (Doctoral thesis; Doktorgradsavhandling, 2016-01-26)
    • Internet-based cognitive behavioural therapy: A novel approach to treating depression in primary care patients 

      Høifødt, Ragnhild Sørensen (Doctoral thesis; Doktorgradsavhandling, 2015-09-15)
      The overall aim of this thesis was to explore the effectiveness and acceptability of a Web-based self-help program (MoodGYM) combined with brief face-to-face therapist support for adult primary care patients with mild to moderate depression. Depression is a highly prevalent disorder causing substantial suffering and impairment. Many depressed patients will receive all their treatment in primary ...