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dc.contributor.authorWaterloo, Svanhild Haugnes
dc.contributor.authorSøgaard, Anne Johanne
dc.contributor.authorAhmed, Luai Awad
dc.contributor.authorDamsgård, Elin
dc.contributor.authorMorseth, Bente
dc.contributor.authorEmaus, Nina
dc.date.accessioned2014-01-07T08:44:01Z
dc.date.available2014-01-07T08:44:01Z
dc.date.issued2013
dc.description.abstractHealth-related quality of life (HRQL) may be associated with increased mortality in the elderly. The effect of prevalent vertebral fractures on HRQL in elderly women and men is not well described. The purpose of this study was to examine the association between prevalent vertebral fractures and back pain, neck pain, and HRQL in elderly women and men, and to study possible gender differences in the reported pain and HRQL. Information on prevalent vertebral fractures was ascertained by a vertebral fracture assessment (VFA) method (dual-energy X-ray absorptiometry (DXA), GE Lunar Prodigy) in 2887 women and men, mean age 65.4 (SD 9.4) who participated in the population-based Tromsø Study which was conducted in 2007–08. Bone mineral density (BMD; g/cm2) was measured by DXA at the femoral sites. Self-reported HRQL was assessed using the standardized measures EQ-5D-3 L and EQ VAS from the EuroQol Group. Lifestyle information was collected by questionnaires. The association between vertebral fractures and pain was analyzed using logistic regression, between vertebral fractures and EQ-5D-3 L and EQ VAS scores by multiple regression analyses. In women, presence of vertebral fractures was associated with an increased risk of back pain with an OR of 1.76 (95% CI: 1.24 – 2.50) after adjustments for age, height, weight, and BMD. Women with vertebral fractures had lower EQ-5D-3 L scores (p < 0.001) than women without vertebral fractures, also after adjustments. These associations were not present in men. Type of fracture was not associated with EQ-5D-3 L scores, but increasing numbers (p < 0.001) and severity of fractures (p < 0.002) were associated with decreasing EQ-5D-3 L score in women. Prevalent vertebral fractures are associated with increased risk of back pain and reduced HRQL in postmenopausal women, but not in men.en
dc.descriptionThis article is part of Svanhild Waterloo's doctoral thesis, available in Munin at <a href=http://hdl.handle.net/10037/5557>http://hdl.handle.net/10037/5557</a>en
dc.identifier.issn1471-2318
dc.identifier.otherFRIDAID 1054165
dc.identifier.otherhttp://dx.doi.org/10.1186/1471-2318-13-102
dc.identifier.urihttps://hdl.handle.net/10037/5695
dc.identifier.urnURN:NBN:no-uit_munin_5402
dc.language.isoengen
dc.publisherBioMed Centralen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801en
dc.subjectVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801en
dc.titleVertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007-08en
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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