Methane emissions from Arctic continental margins are increasing due to the negative effect of global warming on ice sheet and permafrost stability, but dynamics and timescales of seafloor seepage still remain poorly constrained. Here, we examine sediment cores collected from an active seepage area located between 295 and 353 m water depth in the SW Barents Sea, at Leirdjupet Fault Complex. The ...

Within the scope of Industry 4.0, Automated Guided Vehicles (AGVs) are used to streamline logistics through the usage of efficient path finding methods. The current path finding methods in the industry rely on excessive usage of guidance in the shape of magnets, tapes or QR codes on the floor that the AGVs follow to reach their destinations. However, the current methods lack operational flexibility ...

A model of haematopoiesis that links self-organisation with symmetric and asymmetric cell division is presented in this paper. It is assumed that all cell divisions are completely random events, and that the daughter cells resulting from symmetric and asymmetric stem cell divisions are, in general, phenotypically identical, and still, the haematopoietic system has the flexibility to self-renew, ...

Targeted inhibition of the oncogenic BCR-ABL1 fusion protein using the ABL1 tyrosine kinase inhibitor imatinib has become standard therapy for chronic myelogenous leukemia (CML), with most patients reaching total and durable remission. However, a significant fraction of patients develop resistance, commonly due to mutated ABL1 kinase domains. This motivated development of second-generation drugs ...

Distributed applications that span mobile devices, computing clusters, and cloud services, require robust and flexible mechanisms for dynamically loading code. This paper describes lady: a system that augments the .net platform with a highly reliable mechanism for resolving and loading assemblies, and arranges for safe execution of partially trusted code. Key benefits of lady are the low latency and ...

The velocity scaling of blobs, subject to dissipation by either electric currents to the sheaths, or dynamical friction, is studied by numerical simulations where the blob amplitude relative to the background plasma is a free parameter. When subject to dissipation by sheath currents, the radial velocity of a blob depends on the square of its cross field size l, vrad ∼ √l for small l. For large l, ...

<p><i>Context</i>: Because of high charge-to-mass ratio, the nanodust dynamics near the Sun is determined by interplay between the gravity and the electromagnetic forces. Depending on the point where it was created, a nanodust particle can either be trapped in a non-Keplerian orbit, or escape away from the Sun, reaching large velocity. The main source of nanodust is collisional fragmentation of ...

Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of genes such as Amyloid Precursor Protein (APP) into Amyloid-β and Microtubule Associated Protein Tau (MAPT) gene, into hyperphosphorylated Tau tangles being ...

FNs klimapanel har utarbeidet en rekke prognoser for økningen i global middeltemperatur basert på ulike scenarier for ­ut­vik­lingen av utslipp av drivhusgasser og partikler fra menneskelig aktivitet. Disse prognosene er i hovedsak basert på en lang rekke svært komplekse modeller. De mest komplekse, såkalte jordsystemmodeller, omfatter sirkulasjonen i atmosfære og hav, men også isdynamikk, og kjemiske ...