Browsing Artikler, rapporter og annet (medisinsk biologi) by Author "Jamaly, Simin"

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    • Interplay of immune and kidney resident cells in the formation of tertiary lymphoid structures in lupus nephritis 

      Jamaly, Simin; Rakaee, Mehrdad; Abdi, Reza; tsokos, George; Fenton, Kristin Andreassen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-27)
      Kidney involvement confers significant morbidity and mortality in patients with systemic lupus erythematosus (SLE). The pathogenesis of lupus nephritis (LN) involves diverse mechanisms instigated by elements of the autoimmune response which alter the biology of kidney resident cells. Processes in the glomeruli and in the interstitium may proceed independently albeit crosstalk between the two is ...

    • Prognostic Value of Macrophage Phenotypes in Resectable Non–Small Cell Lung Cancer Assessed by Multiplex Immunohistochemistry 

      Rakaee, Mehrdad; Busund, Lill-Tove; Jamaly, Simin; Paulsen, Erna-Elise; Richardsen, Elin; Andersen, Sigve; Al-Saad, Samer; Bremnes, Roy M.; Dønnem, Tom; Kilvær, Thomas Karsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-10)
      Macrophages are important inflammatory cells that regulate innate and adaptive immunity in cancer. Tumor-associated macrophages (TAMs) are thought to differentiate into two main phenotypes: proinflammatory M1 and protumorigenic M2. Currently, the prognostic impact of TAMs and their M1 and M2 phenotypes is unclear in non–small cell cancer (NSCLC). The present study was set up to evaluate an approach ...