Seasonality is evident in several aspects of human health and behavior, whereas seasonality in chronic pain is less well studied. We examined seasonal variation in pain severity and pain dissemination, as well as in pain-associated conditions, such as sleep impairment, sleep timing, mental distress, fatigue and physical activity. We also examined if any of these associated conditions moderated the ...

Ovarian reserve is a key component influencing reproductive function and fertility. Serum anti-Mullerian hormone (AMH) and antral follicle count (AFC) are established quantitative markers of ovarian reserve. The overall aim of this thesis comprising four work packages was to study the role of AMH and AFC on different aspects of fertility and fertility treatment. Their specific objectives were: 1) To ...

Increasing influence of Atlantic water in the Arctic Ocean has the potential to significantly impact regional water temperature and salinity. Here we use a rDNA barcoding approach to reveal how microbial communities are partitioned into distinct assemblages across a gradient of Atlantic-Polar Water influence in the Norwegian Sea. Data suggest that temperate adapted bacteria may replace cold water ...

<p>Background: Age-related epigenetic dysregulations are associated with several diseases, including cancer. The number of stochastic epigenetic mutations (SEM) has been suggested as a biomarker of life-course accumulation of exposure-related DNA damage; however, the predictive role of SEMs in cancer has seldom been investigated. <p>Methods: A SEM, at a given CpG site, was defined as an extreme ...

This dissertation explores the factors that restrict and facilitate adjectivization in Russian, an affixless part-of-speech change leading to ambiguity between participles and adjectives. I develop a theoretical framework based on major approaches to adjectivization, and assess the effect of the factors on ambiguity in the empirical data. I build a linguistic model using the Constraint Grammar ...

As a prerequisite to nondestructive testing of damaged fibered laminates, the Green's function, corresponding with an undamaged structure, and the electromagnetic fields associated with the damaged one are investigated herein. For the undamaged fibered laminate, benefiting from the periodicity of the fibers within each layer, the field solution follows the scattering-matrix-based method using the ...

The aim of this work was to develop a new in vitro lipolysis-permeation model to predict the in vivo absorption of fenofibrate in self-nanoemulsifying drug delivery systems (SNEDDSs). More specifically, the in vitro intestinal lipolysis model was combined with the mucus-PVPA (Phospholipid Vesicle-based Permeation Assay) in vitro permeability model. Biosimilar mucus (BM) was added to the surface of ...

<i>Background</i> - The Russian Federation has very high cardiovascular disease (CVD) mortality rates compared with countries of similar economic development. This cross-sectional study compares the characteristics of CVD-free participants with and without recent primary care contact to ascertain their CVD risk and health status.<br><br> <i>Methods</i> - A total of 2774 participants aged 40–69 ...

<p>Bakgrunn og hensikt: Utfordrende atferd er hyppig forekommende på sykehjem. Hensikten med studien er å få kunnskap om sykepleieres erfaringer med utfordrende atferd hos personer med demens i forsterket skjermet enhet på sykehjem. <p>Metode: Dette er en kvalitativ studie der data er samlet inn ved hjelp av fire semi-strukturerte forskningsintervju. Data er analysert ved å bruke systematisk ...

In the present study, the Incredible Years Teacher Classroom Management (IY TCM) program was implemented as a universal preventive intervention in a regular, lower primary school setting. Outcomes for teacher’s behavior management practice, problem behavior in the classroom and the school environment, teacher self- and collective efficacy, and classroom climate were examined. Using a quasi-experimental ...