Viser treff 25241-25260 av 37157

    • Sea-ice dynamics in an Arctic coastal polynya during the past 6500 years 

      Knies, Jochen; Pathirana, Irene Dorothea; Cabedo-Sanz, Patricia; Banica, Ana; Fabian, Karl; Rasmussen, Tine Lander; Forwick, Matthias; Belt, Simon T. (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-23)
      The production of high-salinity brines during sea-ice freezing in circum-arctic coastal polynyas is thought to be part of northern deep water formation as it supplies additional dense waters to the Atlantic meridional overturning circulation system. To better predict the effect of possible future summer ice-free conditions in the Arctic Ocean on global climate, it is important to improve our ...
    • Structural insight into a CE15 esterase from the marine bacterial metagenome 

      De Santi, Concetta; Gani, Osman A. B. S. M.; Helland, Ronny; Williamson, Adele Kim (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-08)
      The family 15 carbohydrate esterase (CE15) MZ0003, which derives from a marine Arctic metagenome, has a broader substrate scope than other members of this family. Here we report the crystal structure of MZ0003, which reveals that residues comprising the catalytic triad differ from previously-characterized fungal homologs, and resolves three large loop regions that are unique to this bacterial ...
    • Svøpt i myra - Synspunkter på Skjoldehamnfunnets etniske og kulturelle tilknytning 

      Svestad, Asgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2017)
      In 1936 an extraordinary find of a clothed skeleton wrapped in a blanket and covered with birch bark appeared in a bog at Skjoldehamn on Andøya Island. The wrapped body was laid on a reindeer pelt, which in turn was placed on sticks of birch. The grave dates to the 11th century, probably the later half. Compared with relevant Norse, Sámi, and Christian graves and burial customs, the Skjoldehamn grave ...
    • Tidal Energy Loss, Internal Tide Radiation, and Local Dissipation for Two-Layer Tidal Flow over a Sill 

      Arneborg, Lars; Jansson, Pær; Staalstrøm, Andre; Broström, Göran (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-14)
      A simple analytical model for tidal energy loss at fjord sills and its partitioning into local dissipation and radiated internal tides is presented. The analytical model builds on a two-layer assumption with quasi-steady nonlinear flow over the sill and wave radiation in the far field. When the interface is situated above sill level, upstream- and downstream-propagating internal waves are generated ...
    • Diagenetic alteration of benthic foraminifera from a methane seep site on Vestnesa Ridge (NW Svalbard) 

      Schneider, Andrea; Cremiere, Antoine; Panieri, Giuliana; Lepland, Aivo; Knies, Jochen (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-08)
      Anomalously low δ<sup>13</sup>C values in foraminiferal calcite tests are due to diagenetic alteration in methane seep sites. Our study applies diagenetically altered fossil benthic foraminiferal tests as geochemical tracers in reconstructing natural past methane seepage episodes at Vestnesa Ridge offshore NW Svalbard. We combine examinations of the test wall microstructure, mineralogical and stable ...
    • Production, consumption, and migration of methane in accretionary prism of southwestern Taiwan 

      Chen, Nai-Chen; Yang, Tsanyao Frank; Hong, Wei-Li; Chen, Hsuan-Wen; Chen, Hsiao-Chi; Hu, Ching-Yi; Huang, Yu-Chun; Lin, Saulwood; Lin, Li-Hung; Su, Chih-Chieh; Liao, Wei-Zhi; Sun, Chih-Hsien; Wang, Pei-Ling; Yang, Tao; Jiang, Shao-Yong; Liu, Char-Shine; Wang, Yunshuen; Chung, San-Hsiung (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-15)
      To systematically quantify the production, consumption, and migration of methane, 210 sediment cores were collected from offshore southwestern Taiwan and analyzed for their gas and aqueous geochemistry. These data, combined with published results, were used to calculate the diffusive methane fluxes across different geochemical transitions and to develop scenarios of mass balance and constrain deep ...
    • Evaluation of the proliferation marker Ki-67 in a large prostatectomy cohort. 

      Richardsen, Elin; Andersen, Sigve; Al-Saad, Samer; Rakaee, Mehrdad; Nordby, Yngve; Pedersen, Mona Irene; Ness, Nora; Grindstad, Thea K.W.; Movik, Ingeborg; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-15)
      The tumor proliferation index marker Ki-67 is strongly associated with tumor cell proliferation, growth and progression, and is widely used in routine clinicopathological investigation. Prostate cancer is a complex multifaceted and biologically heterogeneous disease, and overtreatment of localized, low volume indolent tumors, is evident. Here, we aimed to assess Ki-67 expression and related ...
    • Supraglacial ponds regulate runoff from Himalayan debris-covered glaciers 

      Irvine-Fynn, Tristram D.L.; Porter, Philip R.; Rowan, Ann V.; Quincey, Duncan J.; Gibson, Morgan J.; Bridge, Jonathan W.; Watson, C. Scott; Hubbard, Alun Lloyd; Glasser, Neil F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-29)
      Meltwater and runoff from glaciers in High Mountain Asia is a vital freshwater resource for one-fifth of the Earth’s population. Between 13% and 36% of the region’s glacierized areas exhibit surface debris cover and associated supraglacial ponds whose hydrological buffering roles remain unconstrained. We present a high-resolution meltwater hydrograph from the extensively debris-covered Khumbu ...
    • Russian Space Meets Western Business Practices - Understanding the Law in the Petroleum Sector in Russia 

      Goes, Sander Bernardus (Journal article; Tidsskriftartikkel; Peer reviewed, 2017)
      This article discusses the relationship between the private international oil company (IOC) Royal Dutch Shell and Russia as an oil producing and oil exporting state during a period when oil prices were moving towards unforeseen heights (2005-2007). By examining this dynamic relationship, this study aims to contribute to an understanding of Russia’s discursive and culturally produced history. The ...
    • Dissemination and Characteristics of a Novel Plasmid-Encoded Carbapenem-Hydrolyzing Class D β-Lactamase, OXA-436, Found in Isolates from Four Patients Involving Six Different Hospitals in Denmark. 

      Samuelsen, Ørjan; Hansen, Frank; Aasnæs, Bettina; Hasman, Henrik; Lund, Bjarte Aarmo; Leiros, Hanna-Kirsti S.; Lilje, Berit; Janice, Jessin; Jakobsen, Lotte; Littauer, Pia; Søes, Lillian M; Holzknecht, Barbara J.; Andersen, Leif P; Stegger, Marc; Andersen, Paal S.; Hammerum, Anette M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-23)
      The diversity of OXA-48-like carbapenemases are continually expanding. In this study, we describe the dissemination and characteristics of a novel class D carbapenemase (CHDL) named OXA-436. In total, six OXA-436-producing Enterobacteriaceae isolates including Enterobacter asburiae (n=3), Citrobacter freundii (n=2) and Klebsiella pneumoniae (n=1) were identified in four patients in the period between ...
    • Unsupervised Estimation of the Equivalent Number of Looks in PolSAR Image with High Heterogeneity 

      Hu, Dingsheng; Qiu, Xiaolan; Anfinsen, Stian Normann; Lei, Bin (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-01)
      Equivalent Number of Looks (ENL) is an important parameter in statistical modelling of multi-look Polarimetric SAR (PolSAR) data. In some automated applications of PolSAR images, it is necessary to estimate the ENL in an unsupervised way without any manual intervention. The existing unsupervised estimation of ENL can not obtain accurate estimates for the images with high heterogeneity. To address ...
    • The relative importance of health, income and social relations for subjective well-being: An integrative analysis 

      Lamu, Admassu Nadew; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-28)
      There is much evidence that health, income and social relationships are important for our well-being, but little evidence on their relative importance. This study makes an integrative analysis of the relative influence of health related quality of life (HRQoL), household income and social relationships for subjective well-being (SWB), where SWB is measured by the first three of the five items on the ...
    • Yes, health is important, but as much for its importance via social life: The direct and indirect effects of health on subjective well‐being in chronically ill individuals 

      Lamu, Admassu Nadew; Olsen, Jan Abel (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-29)
      There is an increasing evidence that health‐related quality of life, income, and social relationships are important to our subjective well‐being (SWB). Little is known, however, about the specific indirect pathways that link health to SWB via social relationships and income. On the basis of a unique data set of 7 disease groups from 6 OECD‐countries (N = 6,173), we investigate the direct and indirect ...
    • High number of kinome-mutations in non-small cell lung cancers associated with reduced immune response and poor relapse-free survival 

      Helland, Åslaug; Brustugun, Odd Terje; Nakken, Sigve; Halvorsen, Ann Rita; Dønnem, Tom; Bremnes, Roy M.; Busund, Lill-Tove; Sun, Jinchang; Lorenz, Susanne; Solberg, Steinar; Jørgensen, Lars Hilmar; Vodak, Daniel; Myklebost, Ola; Hovig, Eivind; Meza, Leonardo Zepeda (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-07)
      Lung cancer is the leading cause of cancer related death, and the past years’ improved insight into underlying molecular events has significantly improved outcome for specific subsets of patients. In particular, several new therapies that target protein kinases have been implemented, and many more are becoming available. We have investigated lung cancer specimens for somatic mutations in a targeted ...
    • Relationship between marine growth and sea survival of two anadromous salmonid fish species 

      Jensen, Arne Johan; Finstad, Bengt; Fiske, Peder; Forseth, Torbjørn; Rikardsen, Audun H.; Ugedal, Ola (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-12)
      Résumé : L’étude fait état de preuves empiriques appuyant le paradigme de « croissance–survie » chez les phases marines de l’omble chevalier (Salvelinus alpinus) et de la truite de mer (Salmo trutta). Ce paradigme postule que les individus plus grands ou a` croissance plus rapide sont plus susceptibles de survivre que leurs conspécifiques plus petits ou a` croissance plus lente. Nous avons utilisé ...
    • Benthic foraminifera as bio-indicators of chemical and physical stressors in Hammerfest harbor (Northern Norway) 

      Dijkstra, Noortje; Junttila, Juho; Skirbekk, Kari; Carroll, JoLynn; Husum, Katrine; Hald, Morten (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-01)
      We investigated benthic foraminiferal assemblages in contaminated sediments in a subarctic harbor of northern Norway to assess their utility as indicators of anthropogenic impacts. Sediments in the harbor are repositories for POPs and heavy metals supplied through discharges from industry and shipping activities. Sediment contaminant concentrations are at moderate to poor ecological quality ...
    • Nonstationary and Chaotic Dynamics in Age-Structured Population Models 

      Wikan, Arild; Kristensen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-08-06)
      The dynamics from nonlinear discrete age-structured population models is under consideration. Focus is on bifurcations, as well as nonstationary and chaotic dynamics. We also explore different mechanisms which may lead to periodic phenomena. Some new results are also presented, in particular from models where both fecundity and survival terms contain nonlinear elements.
    • Prognostic significance of S100A4-expression and subcellular localization in early-stage breast cancer 

      Egeland, Eivind Valen; Pedersen, Kjetil Boye; Park, Daehoon; Synnestvedt, Marit; Sauer, Torill; The Oslo Breast Cancer Consortium (OSBREAC); Naume, Bjørn; Borgen, Elin; Mælandsmo, Gunhild (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-01-05)
      Purpose: <br> Prognostic factors are useful in order to identify early-stage breast cancer patients who might benefit from adjuvant treatment. The metastasis-promoting protein S100A4 has previously been associated with poor prognosis in breast cancer patients. The protein is expressed in diverse subcellular compartments, including the cytoplasm, extracellular space, and nucleus. Nuclear expression ...
    • Gatekeepers to the effects of climate warming? Niche construction restricts plant community changes along a temperature gradient 

      Bråthen, Kari Anne; Gonzalez, Victoria; Yoccoz, Nigel Gilles (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-06-20)
      Organisms that modify the environment (niche constructors) are likely candidates to mediate the effects of climate warming. Here we assess tundra plant community changes along a temperature gradient and how these are modified in the presence of the common allelopathic dwarf shrub Empetrum nigrum and the large herbivore Rangifer tarandus. 2 We developed a structural equation model based on data ...
    • Carbon stocks and fluxes in the high latitudes: Using site-level data to evaluate Earth system models 

      Chadburn, Sarah E.; Krinner, Gerhard; Porada, Philipp; Bartsch, Annett; Beer, Christian; Belelli Marchesini, Luca; Boike, Julia; Ekici, Altug; Elberling, Bo; Friborg, Thomas; Hugelius, Gustaf; Johansson, Margareta; Kuhry, Peter; Kutzbach, Lars; Langer, Moritz; Lund, Magnus; Parmentier, Frans-Jan Willem; Peng, Shushi; van Huissteden, Ko; Wang, Tao; Westermann, Sebastian; Zhu, Dan; Burke, Eleanor J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-17)
      It is important that climate models can accurately simulate the terrestrial carbon cycle in the Arctic due to the large and potentially labile carbon stocks found in permafrost-affected environments, which can lead to a positive climate feedback, along with the possibility of future carbon sinks from northward expansion of vegetation under climate warming. Here we evaluate the simulation of tundra ...