Isogenic bacterial cell populations are phenotypically heterogenous and may include subpopulations of antibiotic tolerant or heteroresistant cells. The reversibility of these phenotypes and lack of biomarkers to differentiate functionally different, but morphologically identical cells is a challenge for research and clinical detection. To overcome this, we present ´Cellular Phenotypic Profiling and ...

Background - Limited research has explored balance problems as a prospective risk factor for cardiovascular disease (CVD). This study aimed to characterize the association between balance measures and the risk of incident CVD in a population of 70‐year‐olds.<p> <p>Methods and Results - From 2012 to 2022 a cohort of 4927 older individuals who were CVD free underwent balance assessments using a ...

Background Psychiatric comorbidity is frequent among persons with attention-deficit/hyperactivity disorder (ADHD). Whether pharmacological treatment of ADHD influences the incidence of psychiatric comorbidity is uncertain.<p> <p>Objective To investigate associations and causal relations between pharmacological treatment of ADHD and incidence of subsequent comorbid psychiatric diagnoses. <p>Methods ...

Background - Type I interferons (IFN-I) are potent alarm factors that initiate cancer cell elimination within tumors by the immune system. This critical immune response is often suppressed in aggressive tumors, thereby facilitating cancer immune escape and unfavorable patient outcome. The mechanisms underpinning IFN-I suppression in tumors are incompletely understood. Arginase-1 (ARG1)-expressing ...

In this article we explore two art projects that each, in their own way, thematise Nordic European colonialism and exhibition culture, and the relationship between the two. European Attraction Limited, by the Swedish-Norwegian artist Lars Cuzner and the Sudanese-Norwegian artist Mohamed Ali Fadlabi, was presented in the context of the Bicentenary of the Norwegian Constitution in Oslo in 2014. The ...

MicroRNAs are involved in breast cancer development and progression, holding potential as biomarkers and therapeutic targets or tools. The roles of miR-20a-5p, a member of the oncogenic miR-17-92 cluster, remain poorly understood in the context of breast cancer. In this study, we elucidate the role of miR-20a-5p in breast cancer by examining its associations with breast cancer risk factors and ...

Deidentification methods, which remove directly identifying information, can be useful tools to mitigate the privacy risks associated with sharing healthcare data. However, benchmarks to evaluate deidentification methods are themselves often derived from real clinical data, making them sensitive themselves and therefore harder to share and apply. Given the rapid advances in generative language ...

In data mining, density-based clustering, which entails classifying datapoints according to their distributions in some space, is an essential method to extract information from large datasets. With the advent of software-based radio, ionospheric radars are capable of producing unprecedentedly large datasets of plasma turbulence backscatter observations, and new automatic techniques are needed to ...

Previous studies show differentially expressed long non-coding RNA present in the placenta from women with pre-eclampsia, potentially playing a vital role in the pathogenesis of the complication. In a published microarray study, Ribonuclease P RNA component H1 was decreased in leukocytes from women that later developed pre-eclampsia. We hypothesized that Ribonuclease P RNA component H1 decreased ...

Rapid Atlantification of marine ecosystems in the Svalbard Archipelago (Norway) is posing a threat to the local polar cod (Boreogadus saida) population. In Kongsfjorden, the decreasing population of polar cod is experiencing a shift in their prey community from Arctic to Atlantic zooplankton and fish. Simultaneously, the abundance of Atlantic cod Gadus morhua is increasing. In this study, we explore ...