Viser treff 19141-19160 av 36288

    • Skeletal anomalies and shape variation in diploid and triploid Atlantic salmon (Salmo salar L.) fed different diets 

      Salbuvik, Kevin (Master thesis; Mastergradsoppgave, 2018-11-12)
      Usage of triploid Atlantic salmon (Salmo salar L.) have been of interest for salmon farmers to mitigate interbreeding between farmed and wild population, and to prevent early sexual maturation. Triploids tend to be more prone to develop skeletal deformities than diploids. This may result from inadequate rearing temperatures and/or diet formulation (i.e. low dietary phosphorus). The main objective ...
    • Use of Peptide Arrays for Identification and Characterization of LIR Motifs 

      Rasmussen, Mads Skytte; Birgisdottir, Åsa birna; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-05)
      The mammalian ATG8 proteins (LC3A-C/GABARAP, GABARAPL1, and GABARAPL2) are small ubiquitin-like proteins critically involved in macroautophagy. Their processed C-termini are posttranslationally conjugated to a phosphatidylethanolamine moiety, enabling their insertion into the lipid bilayers of both the inner and outer membranes of the forming autophagosomes. The ATG8s bind a diverse selection of ...
    • Singularly perturbed spectral problems in a thin cylinder with fourier conditions on its bases 

      Piatnitski, Andrey; Rybalko, Volodymyr (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      The paper deals with the bottom of the spectrum of a singularly perturbed second order elliptic operator defined in a thin cylinder and having locally periodic coefficients in the longitudinal direction. We impose a homogeneous Neumann boundary condition on the lateral surface of the cylinder and a generic homogeneous Fourier condition at its bases. We then show that the asymptotic behavior of the ...
    • Structure dependent determination of organophosphate targets in mammalian tissues using activity-based protein profiling 

      Linn, Vivian S; Volk, Regan F; DeLeon, Adrian J; Anderson, Lindsey N; Purvine, Samuel Owen; Shukla, Anil K; Bernstein, Hans Christopher; Smith, Jordan N; Wright, Aaron T (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-24)
      Acute and chronic exposure to organophosphates (OPs), including agricultural pesticides, industrial chemicals, and chemical warfare agents, remain a significant worldwide health risk. The mechanisms by which OPs alter development and cognition in exposed individuals remain poorly understood, in part due to the large number of structurally diverse OPs and the wide range of affected proteins and ...
    • Together and apart. Perfective verbs with a prefix and the semelfactive suffix -nu- in Contemporary Standard Russian 

      Nordrum, Maria (Doctoral thesis; Doktorgradsavhandling, 2020-03-27)
      This dissertation investigates Russian perfective verbs with a prefix and the semelfactive suffix -nu-, such as zaxlopnut’ ‘slam shut’, for the sake of simplicity referred to as “Pref-Nu verbs”. Pref-Nu verbs have received only marginal attention in the scholarly literature, and in the dissertation a main goal is therefore to shed light on their distribution and productivity in Contemporary Standard ...
    • Producing & Playing Hegemonic Pasts: Historical Digital Games as Memory-Making Media 

      Lundedal Hammar, Emil (Doctoral thesis; Doktorgradsavhandling, 2020-04-03)
      This dissertation investigates the relation between digital games and common understandings of the past, which people experience through popular culture, formally called 'cultural memory processes'. Typically, so-called historical digital games depict historical scenarios such as World War II, the Cold War, and more recently, the War on Terror, as also seen in major film productions, TV series, and ...
    • Origin and transformation of light hydrocarbons ascending at an active pockmark on Vestnesa Ridge, Arctic Ocean 

      Pape, Thomas; Buenz, Stefan; Hong, Wei-Li; Torres, Marta E.; Riedel, Matthias; Panieri, Giuliana; Lepland, Aivo; Hsu, Chieh Wei; Wintersteller, Paul; Wallmann, Klaus; Schmidt, Christopher; Yao, Haoyi; Bohrmann, Gerhard (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-25)
      We report on the geochemistry of hydrocarbons and pore waters down to 62.5 mbsf, collected by drilling with the MARUM‐MeBo70 and by gravity coring at the Lunde pockmark in the Vestnesa Ridge. Our data document the origin and transformations of volatiles feeding gas emissions previously documented in this region. Gas hydrates are present where a fracture network beneath the pockmark focusses migration ...
    • Clinicians’ assumptions about Sami culture and experience providing mental health services to Indigenous patients in Norway 

      Dagsvold, Inger; Møllersen, Snefrid; Blix, Bodil Hansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      This qualitative study explores Sami and non-Sami clinicians’ assumptions about Sami culture and their experiences in providing mental health services to Sami patients. The aim is to better understand and improve the ways in which culture is incorporated into mental health services in practice. Semi-structured interviews were conducted with 20 clinicians in mental health outpatient clinics in the ...
    • Effects of Resistance Training on Functional Strength and Muscle Mass in 70-Year-Old Individuals With Pre-sarcopenia: A Randomized Controlled Trial 

      Vikberg, Sanna; Sörlén, Niklas; Brandén, Jonas; Johansson, Jonas; Nordström, Anna; Hult, Andreas; Nordström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-07)
      <i>Objective</i> - Sarcopenia has been defined as age-related loss of muscle mass and function. The aim of this randomized controlled trial was to examine the effects of a 10-week instructor-led resistance training program on functional strength and body composition in men and women aged 70 years with pre-sarcopenia.<p> <p><i>Design, Setting, and Participants</i> - Participants were randomized ...
    • Facet arthropathy evaluation: CT or MRI? 

      Berg, Linda; Thoresen, Hanne; Neckelmann, Gesche F; Furunes, Håvard; Hellum, Christian; Espeland, Ansgar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)
      <i>Objective</i> - To assess the reliability of lumbar facet arthropathy evaluation with computed tomography (CT) or magnetic resonance imaging (MRI) in patients with and without lumbar disc prosthesis and to estimate the reliability for individual CT and MRI findings indicating facet arthropathy.<p> <p><i>Methods</i> - Metal-artifact reducing CT and MRI protocols were performed at follow-up of ...
    • Policy Transfer of Branding and Reputation Management: Motivations, Challenges, and Opportunities for a Small Rural Municipality 

      Lockert, Åshild Skjegstad; Bjørnå, Hilde; Krane, Martin Sollund (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-23)
      This paper seeks to convey a broader understanding of policy transfers between different sectors, focusing on transfers from the for-profit sector to local government. Specifically, we study the reasoning in a transfer process of branding and reputation management policy. Our case is a rural Norwegian municipality struggling to combat depopulation. This study is longitudinal. We discover that some ...
    • Non-use of community health-care services – an exploratory cross-sectional study among family care-givers for older, home-dwelling persons with dementia 

      Moholt, Jill-Marit; Friborg, Oddgeir; Henriksen, Nils Oddbjørn; Hamran, Torunn; Blix, Bodil Hansen (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-05)
      Community health-care services for older, home-dwelling persons with dementia tend to be underutilised. Family care-givers provide substantial care, and they often arrange for and co-ordinate health-care services on behalf of persons with dementia. The aim of this study was to examine family care-givers’ knowledge of unused services and their self-reported reasons for non-use of such services. We ...
    • T-box transcription factor eomesodermin/Tbr2 in Atlantic cod (Gadus morhua L.): Molecular characterization, promoter structure and function analysis 

      Chi, Heng; Sørmo, Kristian Gillebo; Diao, Jing; Dalmo, Roy Ambli (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-11)
      Eomesodermin (Eomes) is a member of T-box transcription factor family and plays an important role in the regulation of a wide variety of developmental processes and immune response in animals. Here we report cloning and characterization of the full-length cDNA of Atlantic cod Eomes (GmEomes), which possesses a TBOX_3 domain similar to its counterpart in mammals. The regulated expression was observed ...
    • Pseudo-anaphylaxis to polyethylene glycol (PEG)-coated liposomes: Roles of anti-PEG IgM and complement activation in a porcine model of human infusion reactions 

      Kozma, Gergely Tibor; Mészáros, Támas; Vashegyi, Ildikó; Fülöp, Tamás Gábor; Örfi, Erik; Dézsi, László; Rosivall, László; Bavli, Yaelle; Urbanics, Rudolf; Mollnes, Tom Eirik; Barenholz, Yechezkel; Szebeni, János (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-26)
      Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild to severe hypersensitivity reactions (HSRs), which can occasionally be life threatening or even lethal. The phenomenon represents an unsolved immune barrier to the use of these drugs, yet its mechanism is poorly understood. This study showed that a single i.v. injection in pigs of a low dose of PEGylated liposomes (Doxebo) induced ...
    • Association of menopausal characteristics and risk of coronary heart disease: A pan-European case-cohort analysis 

      Dam, Veerle; van der Schouw, Yvonne T.; Onland-Moret, N. Charlotte; Groenwold, Rolf H.H.; Peters, Sanne A.E.; Burgess, Stephen; Wood, Angela M.; Chirlaque, Maria-Dolores; Moons, Karel G.M.; Oliver-Williams, Clare; Schuit, Ewoud; Tikk, Kaja; Weiderpass, Elisabete; Holm, Marianne; Tjønneland, Anne; Kühn, Tilman; Fortner, Renée T.; Trichopoulou, Antonia; Karakatsani, Anna; La Vecchia, Carlo; Ferrari, Pietro; Gunter, Marc; Masala, Giovanna; Sieri, Sabina; Tumino, Rosario; Panico, Salvatore; Boer, Jolanda M.A.; Verschuren, W.M. Monique; Salamanca-Fernández, Elena; Arriola, Larraitz; Moreno-Iribas, Conchi; Engström, Gunnar; Melander, Olle; Nordendahl, Maria; Wennberg, Patrik; Key, Timothy J.; Colorado-Yohar, Sandra; Matullo, Giuseppe; Overvad, Kim; Clavel-Chapelon, Francoise; Boeing, Heiner; Ramõn Quirõs, Jose; di Angelantonio, Emanuele; Langenberg, Claudia; Sweeting, Michael J.; Riboli, Elio; Wareham, Nicholas J.; Danesh, John; Butterworth, Adam (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)
      <i>Background</i> - Earlier age at menopause has been associated with increased risk of coronary heart disease (CHD), but the shape of association and role of established cardiovascular risk factors remain unclear. Therefore, we examined the associations between menopausal characteristics and CHD risk; the shape of the association between age at menopause and CHD risk; and the extent to which these ...
    • Thermal habitat of adult Atlantic salmon Salmo salar in a warming ocean 

      Strøm, John Fredrik; Thorstad, Eva Bonsak; Rikardsen, Audun (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-29)
      The year‐round thermal habitat at sea for adult Atlantic salmon <i>Salmo salar</i> (<i>n</i> = 49) from northern Norway was investigated using archival tags over a 10 year study period. During their ocean feeding migration, the fish spent 90% of the time in waters with temperatures from 1.6–8.4°C. Daily mean temperatures ranged from −0.5 to 12.9°C, with daily temperature variation up to 9.6°C. Fish ...
    • Temporal trend of mercury in relation to feeding habits and food availability in arctic foxes (Vulpes lagopus) from Svalbard, Norway 

      Hallanger, Ingeborg G.; Fuglei, Eva; Yoccoz, Nigel Gilles; Pedersen, Åshild Ønvik; König, Max; Routti, Heli Anna Irmeli (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-20)
      We investigated the temporal trend of mercury (Hg) in arctic foxes from Svalbard, Norway sampled in the period 1997–2014 (<i>n</i> = 109, from 11 trapping seasons). We used linear models to investigate the effect of trapping season, feeding habits (δ<sup>13</sup>C), food availability from marine and terrestrial ecosystems (reindeer carcasses and sea ice cover), sex, age and body condition on liver ...
    • Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP) 

      Timp, Jasmijn F.; Brækkan, Sigrid Kufaas; Lijfering, Willem M.; van Hylckama Vlieg, Astrid; Hansen, John-Bjarne; Rosendaal, Frits Richard; le Cessie, Saskia; Cannegieter, Suzanne C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-11)
      <i>Background</i> - Recurrent venous thromboembolism (VTE) is common. Current guidelines suggest that patients with unprovoked VTE should continue anticoagulants unless they have a high bleeding risk, whereas all others can stop. Prediction models may refine this dichotomous distinction, but existing models apply only to patients with unprovoked first thrombosis. We aimed to develop a prediction ...
    • The effect of maternal and paternal height and weight on antenatal, perinatal and postnatal morphology in sex-stratified analyses 

      Skåren, Lise Hansen; Davies, Braidy; Bjørnerem, Åshild (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-10)
      <i>Introduction</i> - Low birthweight is associated with diseases later in life. The mechanisms for these associations are not well known. If the hypothesis concerning “maternal constraint” is correct for humans, as shown in animal experiments, we expect the maternal, not paternal, body proportions to influence antenatal growth and those of both parents to influence postnatal growth. We aimed to ...
    • Disappearing green: Shrubs decline and bryophytes increase with nine years of increased snow accumulation in the High Arctic 

      Cooper, Elisabeth J.; Little, Chelsea J.; Pilsbacher, Anna Katharina; Mörsdorf, Martin Alfons (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-25)
      <i>Question</i> - How does increased snow depth affect plant community composition of High Arctic tundra, and can the Normalized Differential Vegetation Index (NDVI) detect induced changes?<p><p> <i>Location</i> - Adventdalen, Spitsbergen, Svalbard (78°10′ N, 16°04′ E).<p><p> <i>Methods</i> - We manipulated snow depth on the tundra using fences, resulting in <i>Deep, Medium</i>, and ...