Institutt for samfunnsmedisin: Nye registreringer
Viser treff 1621-1640 av 2035
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Overweight and Weight Gain Predict Psoriasis Development in a Population-based Cohort
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-07)Overweight is a proposed risk factor for psoriasis. However, evidence from prospective studies is limited. The aim of this study was to investigate the association between overweight, weight gain and risk of psoriasis, and potential synergism with smoking, within a population-based cohort including 8,752 individuals followed from 1994 up to 2008. There was a 32% increased odds of psoriasis from a ... -
Differential Recall Bias, Intermediate Confounding, and Mediation Analysis in Life Course Epidemiology: An Analytic Framework with Empirical Example
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-23)The mechanisms by which childhood socioeconomic status (CSES) affects adult mental health, general health, and well-being are not clear. Moreover, the analytical assumptions employed when assessing mediation in social and psychiatric epidemiology are rarely explained. The aim of this paper was to explain the intermediate confounding assumption, and to quantify differential recall bias in the ... -
Resisting 'reason'. A Comparative Anthropological Study of Social Differences and Resistance Toward Health Promotion and Illness Prevention In Denmark
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-30)Social differences in health and illness are well-documented in Denmark. However, very little is known about how health practices manifest in the everyday lives of different social classes. We propose acts of resistance and formation of health subjectivities as helpful concepts to develop our understanding of how dominant health discourses are appropriated by different social classes and transformed ... -
Smoking and risk of ovarian cancer by histological subtypes: an analysis among 300 000 Norwegian women.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-12-13)Background: We prospectively investigated the association between different measures of smoking exposure and the risk of serous, mucinous, and endometrioid ovarian cancers (OC) in a cohort of more than 300 000 Norwegian women. <br>Methods: We followed 300 398 women aged 19–67 years at enrolment until 31 December 2013 for OC incidence through linkage to national registries. We used Cox proportional ... -
Use pattern for contraceptive implants in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-19)Introduction: Knowledge about global use patterns of contraceptive implants is limited. This study aims to describe implant use patterns from a user and prescriber perspective. <p> Material and methods: In a cross-sectional design, we estimated the annual number of users by calculating doses sold per 1000 women-years in the Norwegian Prescription Database for the years 2006-2012. For each ... -
Alcohol and suicide in the Nenets Autonomous Okrug and Arkhangelsk Oblast, Russia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-23)Background. High suicide rates in the Russian North are coupled with high alcohol consumption in the described populations. Objective. To investigate the potential role of alcohol consumption on suicides in the Nenets Autonomous Okrug (NAO) in 2002 2012 and to compare this information with corresponding data from the neighboring Arkhangelsk Oblast (AO). Design. Retrospective population-based ... -
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-27)Common variants in 94 loci have been associated with breast cancer including 15 loci with genome-wide significant associations (P<5 × 10−8) with oestrogen receptor (ER)-negative breast cancer and BRCA1-associated breast cancer risk. In this study, to identify new ER-negative susceptibility loci, we performed a meta-analysis of 11 genome-wide association studies (GWAS) consisting of 4,939 ER-negative ... -
Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-09)Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and identify common loci associated with risk, we conducted a meta-analysis of four genome-wide association studies (GWAS) composed of 3,100 cases and 7,667 controls with follow-up replication in 1,958 cases and 5,530 controls. Here we report three new ... -
Coffee consumption and the risk of malignant melanoma in the Norwegian Women and Cancer (NOWAC) Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-29)Background: Coffee contains biologically-active substances that suppress carcinogenesis in vivo, and coffee consumption has been associated with a lower risk of malignant melanoma. We studied the impact of total coffee consumption and of different brewing methods on the incidence of malignant melanoma in a prospective cohort of Norwegian women. <p>Methods: We had baseline information on total ... -
Pre-diagnostic body mass index and weight change in relation to colorectal cancer survival among incident cases from a population-based cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-07)Background:<br> Whether excess body weight influences colorectal cancer (CRC) survival is unclear. We studied pre-diagnostic body mass index (BMI) and weight change in relation to CRC-specific mortality among incident CRC cases within a large, Norwegian cohort.<br> Methods:<br> Participants’ weight was measured at health examinations up to three times between 1974 and 1988. CRC cases were ... -
Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-06)Background:<br> Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated ... -
Major postoperative complications are associated with impaired long-term survival after gastro-esophageal and pancreatic cancer surgery: a complete national cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-18)Background: Some studies have reported an association between complications and impaired long-term survival after cancer surgery. We aimed to investigate how major complications are associated with overall survival after gastro-esophageal and pancreatic cancer surgery in a complete national cohort. <br> Methods: All esophageal-, gastric- and pancreatic resections performed for cancer in Norway ... -
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-08)Background:<br> Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth ... -
Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07)PURPOSE:<br> To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes. <br> METHODS:<br> Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucatu- Brazil and surrounding region. ... -
Priority setting for improvement of cervical cancer prevention in Iran
(Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-22)Background:<br> Cervical cancer is the fourth most common cancer among women worldwide. Organized cervical screening and vaccination against human papilloma virus (HPV) have been successful interventions for prevention of invasive cervical cancer (ICC). Because of cultural and religious considerations, ICC has low incidence in Iran and many other Muslim countries. There is no organized cervical ... -
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-23)Large consortia have revealed hundreds of genetic loci associated with anthropometric traits, one trait at a time. We examined whether genetic variants affect body shape as a composite phenotype that is represented by a combination of anthropometric traits. We developed an approach that calculates averaged PCs (AvPCs) representing body shape derived from six anthropometric traits (body mass index, ... -
Quantification of the smoking-associated cancer risk with rate advancement periods: Meta-analysis of individual participant data from cohorts of the CHANCES consortium
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-04-05)Background:<br> Smoking is the most important individual risk factor for many cancer sites but its association with breast and prostate cancer is not entirely clear. Rate advancement periods (RAPs) may enhance communication of smoking related risk to the general population. Thus, we estimated RAPs for the association of smoking exposure (smoking status, time since smoking cessation, smoking ... -
Modifiable causes of premature death in middle-age in Western Europe: Results from the EPIC cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-14)Background<br> Life expectancy is increasing in Europe, yet a substantial proportion of adults still die prematurely before the age of 70 years. We sought to estimate the joint and relative contributions of tobacco smoking, hypertension, obesity, physical inactivity, alcohol and poor diet towards risk of premature death.<br> Methods<br> We analysed data from 264,906 European adults from the ... -
A method for sensitivity analysis to assess the effects of measurement error in multiple exposure variables using external validation data
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-13)Background:<br>Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a disease. The association can be distorted further by mismeasured confounders, leading to invalid results and conclusions. It is, however, difficult to adjust for the bias in the association when there is no internal validation ... -
Acute high-dose and chronic lifetime exposure to alcohol consumption and differentiated thyroid cancer: T-CALOS Korea
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-17)Background:<br> This study evaluated the effects of acute high-dose and chronic lifetime exposure to alcohol and exposure patterns on the development of differentiated thyroid cancer (DTC).<br> Methods:<br> The Thyroid Cancer Longitudinal Study (T-CALOS) included 2,258 DTC patients (449 men and 1,809 women) and 22,580 healthy participants (4,490 men and 18,090 women) who were individually ...