Viser treff 5009-5028 av 10096

    • Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice 

      Andreassen, Monica; Bøhn, Thomas; Wikmark, Odd Gunnar; Bodin, Johanna; Traavik, Terje; Løvik, Martinus; Nygaard, Unni Cecilie (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05-04)
      BACKGROUND In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize, expressing the insecticidal Cry1Ab toxin, is grown in many countries worldwide. In animal models, intranasal and intraperitoneal immunisations with the purified Cry1Ab proteins have induced immune responses, and feeding ...
    • Invisible Differentness in Sámi Child Protection Services 

      Douglas, Marcela; Saus, Merete (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-21)
      The paper explores what lies behind the development of Sámi child protection services in practice. The study is an empirical investigation of how policymakers and child welfare leaders reflect on the challenges and opportunities in this field. All the twelve participants in the study worked in northernmost counties of Norway that are part of the Sámi-language administrative district. Although Norwegian ...
    • Invisible emotional expressions influence social judgments and pupillary responses of both depressed and non-depressed individuals. 

      Laeng, Bruno; Sæther, Line; Holmlund, Terje; Wang, Catharina E.; Waterloo, Knut; Eisemann, Martin; Halvorsen, Marianne (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      We used filtered low spatial frequency images of facial emotional expressions (angry, fearful, happy, sad, or neutral faces) that were blended with a high-frequency image of the same face but with a neutral facial expression, so as to obtain a “hybrid” face image that “masked” the subjective perception of its emotional expression. Participants were categorized in three groups of participants: healthy ...
    • Involuntary admission in Norwegian adult psychiatric hospitals: A systematic review 

      Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-22)
      Background: It is an important objective of the psychiatric services to keep the use of involuntary procedures to a minimum, as the use of coercion involves clinical, ethical, and legal issues. It has been claimed that Norway has a relatively high rate of involuntary admissions. We reviewed the peer-reviewed literature on the use of involuntary admission in Norway, with the purpose of identifying ...
    • Involuntary psychiatric admission: how the patients are detected and the general practitioners' expectations for hospitalization. An interview-based study 

      Røtvold, Ketil; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-08)
      <p>Background: In Norway, it is usually GPs that refer patients to involuntary admission. A high proportion of such referrals come from out-of-hours clinics. Little is known about who first initiate the contact between the patients and the referring doctors and which expectations the referring doctors have with respect to the involuntary admissions. The aim of the study was to examine who first ...
    • Involvement in research and development projects among community-working occupational therapists in Norway 

      Bonsaksen, Tore; Dolva, Anne-Stine; Hagby, Cathrine; Sveen, Unni; Horghagen, Sissel; Thyness, Else Merete; Arntzen, Cathrine (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-31)
      A cross-sectional descriptive survey was conducted (n = 561). Almost half of the participants took part in research and development projects. Being involved in research and development was associated with lower age, having further education, and higher levels of work experience. The current and prioritized research topics were reablement and assistive technology. The study implies that community-working ...
    • Involvement of A13 dopaminergic neurons in prehensile movements but not reward in the rat 

      Garau, Celia; Hayes, Jessica; Chiacchierini, Giulia; Mccutcheon, James Edgar; Apergis-Schoute, John (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-09)
      Tyrosine hydroxylase (TH)-containing neurons of the dopamine (DA) cell group A13 are well positioned to impact known DA-related functions as their descending projections innervate target regions that regulate vigilance, sensory integration, and motor execution. Despite this connectivity, little is known regarding the functionality of A13-DA circuits. Using TH-specific loss-of-function methodology ...
    • Involvement of aph(3')-IIa in the formation of mosaic aminoglycoside resistance genes in natural environments 

      Woegerbauer, Markus; Kuffner, Melanie; Domingues, Sara; Nielsen, Kaare Magne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-19)
      Intragenic recombination leading to mosaic gene formation is known to alter resistance profiles for particular genes and bacterial species. Few studies have examined to what extent aminoglycoside resistance genes undergo intragenic recombination. We screened the GenBank database for mosaic gene formation in homologs of the aph(3′)-IIa (nptII) gene. APH(3′)-IIa inactivates important aminoglycoside ...
    • Involvering av foreldre i behandling av prosedyresmerter i en NICU. Hvilke ikke-medikamentelle metoder kan foreldre bruke for å lindre prosedyrerelaterte smerter i en nyfødtintensivavdeling? 

      Sunio, Enni; Kosonen, Liisi (Master thesis; Mastergradsoppgave, 2020-06-02)
      <p><i>Bakgrunn:</i> Barn i en NICU blir utsatt for gjentatte smertefulle prosedyrer under innleggelse som kan påvirke barnets utvikling negativt. Dette forårsaker mye stress hos foreldre og kan påvirke foreldre/barn-tilknytningen. De fleste foreldre ønsker å delta i smertelindring, men trenger aktiv støtte og veiledning fra personalet. Bruk av ikke-medikamentelle metoder når det gjelder lindring av ...
    • Iodine intake in Norwegian women and men: The population-based Tromsø Study 2015–2016 

      Madar, Ahmed Ali; Heen, Espen Kolstad; Hopstock, Laila Arnesdatter; Carlsen, Monica Hauger; Meyer, Haakon E (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-23)
      Ensuring sufficient iodine intake is a public health priority, but we lack knowledge about the status of iodine in a nationally representative population in Norway. We aimed to assess the current iodine status and intake in a Norwegian adult population. In the population-based Tromsø Study 2015–2016, 493 women and men aged 40–69 years collected 24-h urine samples and 450 participants also completed ...
    • Iohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 2: Why to measure glomerular filtration rate with iohexol? 

      Delanaye, Pierre; Melsom, Toralf; Ebert, Natalie; Bäck, Sten-Erik; Mariat, Christophe; Cavalier, Etienne; Björk, Jonas; Christensson, Anders; Nyman, Ulf; Porrini, Esteban; Remuzzi, Giuseppe; Ruggenenti, Piero; Schaeffner, Elke; Soveri, Inga; Sterner, Gunnar; Eriksen, Bjørn Odvar; Gasperi, Flavia (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-09)
      A reliable assessment of glomerular filtration rate (GFR) is of paramount importance in clinical practice as well as epidemiological and clinical research settings. It is recommended by Kidney Disease: Improving Global Outcomes guidelines in specific populations (anorectic, cirrhotic, obese, renal and non-renal transplant patients) where estimation equations are unreliable. Measured GFR is the ...
    • Iohexol plasma clearance for measuring glomerular filtration rate in clinical practice and research: a review. Part 1: How to measure glomerular filtration rate with iohexol? 

      Delanaye, Pierre; Ebert, Natalie; Melsom, Toralf; Gasperi, Flavia; Mariat, Christophe; Cavalier, Etienne; Björk, Jonas; Christensson, Anders; Nyman, Ulf; Porrini, Esteban; Remuzzi, Giuseppe; Ruggenenti, Piero; Schaeffner, Elke; Soveri, Inga; Sterner, Gunnar; Eriksen, Bjørn Odvar; Bäck, Sten-Erik (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-08-23)
      While there is general agreement on the necessity tomeasure glomerular filtration rate (GFR) inmany clinical situations, there is less agreement on the bestmethod to achieve this purpose.As the gold standardmethod for GFR determination, urinary (or renal) clearance of inulin, fades into the background due to inconvenience and high cost, a diversity of filtrationmarkers and protocols compete to ...
    • Iohexol Plasma Clearance: Impact of Weighing the Syringe 

      Delanaye, Pierre; Melsom, Toralf; Cavalier, Etienne; Pottel, Hans; Eriksen, Bjørn Odvar; Dubourg, Laurence (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-05)
      Measured glomerular filtration rate (mGFR) measurement is necessary in specific patients and/or specific clinical contexts.1–3 Plasma clearances are the preferred methods, as they are less costly and cumbersome than urinary clearances.4 The contrast medium iohexol is the most commonly used worldwide, partly for pragmatic reasons, as this marker is stable, not radioactive, and its measurement ...
    • Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts 

      Grinde, Maria Tunset; Vik, Jørg; Camilio, Ketil Andre; Martinez-Zubiaurre, Inigo; Hellevik, Turid (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-25)
      Cancer-associated fibroblasts (CAFs) are abundantly present in solid tumors and affect tumorigenesis and therapeutic responses. In the context of clinical radiotherapy, the impact of irradiated CAFs to treatment outcomes is largely unexplored. Aiming at improving radiotherapy efficacy, we have here explored the effect of radiation on the inherent pro-tumorigenic capacity of CAFs in animals. Ionizing ...
    • Ionizing radiation curtails immunosuppressive effects from cancer-associated fibroblasts on dendritic cells 

      Berzaghi, Rodrigo; Tornaas, Stian; Lode, Kristin; Hellevik, Turid; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-09)
      Cancer-associated fibroblasts (CAFs) participate actively in tumor development and affect treatment responses, by among other mechanisms, promoting an immunosuppressive tumor microenvironment. In contrast to normal fibroblasts, reactive CAFs secrete a myriad of immunomodulatory soluble factors at high levels, i.e. growth factors, cytokines, and chemokines, which directly influence tumor immunity and ...
    • IP i Psykisk helsetjeneste. Bruk av individuell plan i psykisk helsetjeneste - en kvalitativ studie 

      Pedersen, Anne-Lise (Master thesis; Mastergradsoppgave, 2017-05-08)
      Studien har som formål å øke kunnskap og forståelse for utfordringer Psykisk helsearbeidere i kommunen erfarer med bruk av individuell plan i psykisk helsetjeneste.
    • IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy 

      Wergeland, Ida; Pullar, Nadine Durema; Assmus, Jörg; Ueland, Thor; Tonby, Kristian; Feruglio, Siri; Kvale, Dag; Damås, Jan Kristian; Aukrust, Pål; Mollnes, Tom Eirik; Dyrhol-Riise, Anne Ma (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-15)
      Objectives: Biomarkers for diagnosis and therapy efficacy in tuberculosis (TB) are requested. We have studied biomarkers that may differentiate between active and latent TB infection (LTBI), the influence of HIV infection and changes during anti-TB chemotherapy. Methods: Thirty-eight plasma cytokines, assessed by multiplex and enzyme immunoassays, were analyzed in patients with active TB before ...
    • Ipsilateral hemisfærehevelse som prediktor for dårlig klinisk status og utkomme ved kronisk subduralt hematom 

      Woll, Benedikte Cecilie (Master thesis; Mastergradsoppgave, 2015-05-31)
      Formål: Pasienter med kronisk subduralt hematom kan raskt fallere og bli kritisk dårlig med behov for akutt kirurgi. Å forutse hvilke pasienter dette gjelder er vanskelig, spesielt siden det man ser på CT-bildene ikke nødvendigvis samsvarer med den kliniske utviklingen. Denne studien undersøker om hevelse i ipsilateral cerebral hemisfære er mulig å kvantifisere på CT-bilder, og om hevelse i så fall ...
    • IQ as a moderator of outcome in severity of children's mental health status after treatment in outpatient clinics 

      Mathiassen, Børge Idar; Brøndbo, Per Håkan; Waterloo, Knut; Martinussen, Monica; Eriksen, Mads; Hanssen-Bauer, Ketil; Kvernmo, Siv (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Psychotherapy is an effective treatment for mental health disorders, but even with the most efficacious treatment, many patients do not experience improvement. Moderator analysis can identify the conditions under which treatment is effective or whether there are factors that can attenuate the effects of treatment. In this study, linear mixed model analysis was used to examine whether the Full Scale ...
    • IQ as a Predictor and Moderator of Children’s Mental Health Status 

      Mathiassen, Børge (Doctoral thesis; Doktorgradsavhandling, 2015-01-27)