Alzheimers sykdom er den vanligste årsaken til demens, dernest karsykdom som forårsaker vaskulær demens. De fleste som får Alzheimers demens etter 65 års alder (late onset Alzheimer’s Disease, LOAD), har ikke sykdommen i familien fra tidligere. Men opptil 25 % av dem som får LOAD, har biologiske slektninger med LOAD. Personer i familier med opphopning av LOAD, har økt risiko for å få LOAD. Det er ...

The use of quality-adjusted life years (QALYs) as a commensurable health outcome measure has been encouraged by health authorities in many countries in order to aid decisions on healthcare priorities. A key methodological challenge is to estimate the weights used for valuing health-related quality of life, i.e. the “Q” in QALY, based on people’s preferences. Such generic preference-based measures ...

Musicians are known to have an increased prevalence of hearing loss and tinnitus due to noise-induced cochlear damage. Rock music is popularly considered a major culprit in terms of excessive sound levels, but the literature on hearing in rock musicians is sparse. In this dissertation the hearing levels of a large number of rock musicians are assessed in relation to factors such as degree of exposure, ...

This thesis investigates the relevance of family and community involvement for culturally adequate social work in Indigenous communities. The study is qualitative and comparative. I compare social work within Indigenous communities in Norway and Montana with the aim of adding to the available knowledge regarding culturally adequate social work in these communities. The thesis consists of three ...

Mange pasienter med en førstegangspsykose får behandling sent i forløpet og har en lang varighet av ubehandlet psykose (VUP). Forsinket behandling kan skyldes både indre (lidelse og pasient relaterte) og ytre (tjeneste og systemrelaterte) faktorer. Til tross for at nyere forskning har dokumentert at en stor del av forsinkelsen skjer mens pasienten mottar behandling i spesialisthelsetjenesten, så er ...

Being active is a primary necessity in life, but it is also an essential part of what makes life worth living. This thesis explored goal pursuit activities people might not experience as pleasant in the moment, but where the self-chosen activities are still considered good and worthwhile. We hypothesized that online self-regulation interventions would be effective in increasing effortful physical ...

<p>You cannot imagine powering through the day without your favorite beverage being on your desk all the time. Have you ever wondered what the consequences might be? </p> <p>It seems that even before you have opened your eyes, there’s already a kettle on the stove or the coffee machine is purring. On the way to work, you have another cup to go from the nearby coffee chop. Long meetings demand ...

Enterococcus faecium is a ubiquitous bacterium that only recently emerged as a nosocomial pathogen. Infections mostly affect immunocompromised patients and multi-resistance of E. faecium often hampers treatment. This thesis focuses on determinants, which give pathogenic potential to E. faecium. In the first paper, two TirE proteins are described as novel virulence factors of E. faecium. The tirE ...

Communication aids can assist patients in obtaining the necessary information about their disease and treatment options. In this study, we explored the effect of two such communication aids: A question prompt list (QPL) and a consultation audio record (CAR) for the patients to bring home. A QPL is a list of suggested questions patients might want to ask their doctor. The Australian QPL “So you ...

Staphylococcus aureus is an efficient human colonizer and pathogen. S.aureus' ability to colonize and/or cause infections in humans is due to its expression of many virulence factors. These virulence factors aid the bacterium in adhering, invading and evading the host´s immune defences. This study focused on exploring the role of two cell wall anchored proteins: Serine-aspartate containing protein ...