Now showing items 61-80 of 703

    • The patient´s role in undergraduate health students' interprofessional clinical placements 

      Jensen, Catrine Buck (Doctoral thesis; Doktorgradsavhandling, 2023-06-16)
      Changed demographics and the prevalence of chronic, non-communicable, and infectious diseases create challenges in healthcare - lack of resources forces a transition from one-to-one to team-based approaches. Health professional education must prepare undergraduates for collaborative practice to ensure a collaborative-ready workforce that involves the patient as a partner. Interprofessional education ...
    • D-dimer for diagnosis and risk assessment of first and recurrent venous thromboembolism 

      Rinde, Fridtjof Balteskard (Doctoral thesis; Doktorgradsavhandling, 2023-06-15)
      Venøs tromboembolisme (VTE) er en samlebetegnelse på dyp venetrombose (DVT) og lungeemboli. D-dimer, en blodprøve for koagulasjon og fibrinolyse, har vært en sentral del av VTE-diagnostikken i flere tiår. Blodprøven D-dimer har flere bruksområder og kan dermed reflektere ulike aspekter ved VTE. I denne avhandlingen har vi undersøkt i) om det er trygt og effektivt å bruke D-dimer uten samtidig bruk ...
    • Stroke rehabilitation. A mixed method study evaluating a novel physiotherapy intervention and patients’ experiences 

      Sivertsen, Marianne (Doctoral thesis; Doktorgradsavhandling, 2023-06-15)
      In this thesis, the possible benefits and challenges regarding taking part in a comprehensive individualized physiotherapy intervention, called I-CoreDIST and usual care physiotherapy following an acute stroke, along with patient perceptions of participation along the rehabilitation continuum are addressed. This is a mixed method study consisting of a randomised controlled trial (RCT) and an in-depth ...
    • Evolutionary genomics of cowpox virus and recombination in vitro between a naturally occurring cowpox virus and a vaccinia virus vectored influenza vaccine 

      Diaz Cánova, Diana Karina (Doctoral thesis; Doktorgradsavhandling, 2023-06-02)
      Modified vaccinia virus Ankara (MVA) is a promising orthopoxvirus (OPXV) vector vaccine candidate due to its host range restriction and good safety profile as a smallpox vaccine. It has been widely tested in clinical trials as a recombinant vector for vaccination against infectious diseases and cancers in humans and animals. Furthermore, it is being used as a smallpox and Mpox vaccine. However, the ...
    • Physical activity, weight gain, and risk of mortality in adults 

      Sagelv, Edvard Hamnvik (Doctoral thesis; Doktorgradsavhandling, 2023-05-11)
      <p><i>Why:</i> As low physical activity levels associate with ill health and mortality, continuous monitoring of physical activity levels is needed to inform policy. Identifying aetiology causes for the obesity epidemic is important to prevent population weight gain. However, there are still uncertainties on how physical activity and weight at population level associate over time, and how physical ...
    • Persistent Organic Pollutants and Type 2 Diabetes Mellitus. Addressing causality with repeated measurements using novel study designs 

      Charles, Dolley Dixil (Doctoral thesis; Doktorgradsavhandling, 2023-05-05)
      <p><i>Background:</i> Persistent Organic Pollutants (POPs) are chemicals that have negative impacts on the environment and biota and have been investigated as possible risk factors for Type 2 Diabetes Mellitus (T2DM). Other well-established risk factors for T2DM, for example, obesity, increased lipids, and age have been reported to influence human POP concentrations. Previous studies have reported ...
    • Klebsiella pneumoniae in the marine environment 

      Håkonsholm, Fredrik (Doctoral thesis; Doktorgradsavhandling, 2023-04-26)
      <p><i>Klebsiella pneumoniae</i> is an opportunistic pathogen present in a wide range of environments. This species is often associated with antibiotic resistance and is a leading cause of health care associated infections but can also cause community acquired infections. Even though <i>K. pneumoniae</i> is extensively studied in clinical settings, less is known about its prevalence, antibiotic ...
    • All roads lead to the lysosome: exploring the degradation of TNIP1 by selective autophagy 

      Rasmussen, Nikoline Lander (Doctoral thesis; Doktorgradsavhandling, 2023-04-21)
      Selective autophagy is important for maintaining cellular homeostasis. Generally, autophagy is considered cytoprotective and anti-inflammatory, acting to limit infection and accumulation of deleterious material. Key to this function is the ability to select cargo to be degraded, and here, selective autophagy receptors play a central role. In this thesis, we show that the anti-inflammatory and ...
    • Dental composites - The effects of matrix composition, suboptimal light curing and water exposure 

      Wikant, Aksel (Doctoral thesis; Doktorgradsavhandling, 2023-03-30)
      In Scandinavian countries, resin-based composite materials have been used in restorative dentistry for over 30 years, replacing dental amalgams. Composite materials based on dimethacrylates provide better aesthetics and treatment options. However, according to in-vitro findings, dental composites can be affected by water, potentially reducing the longevity of dental restorations. The proper ...
    • Three essays on health and labour market participation 

      Berthung, Espen (Doctoral thesis; Doktorgradsavhandling, 2023-03-23)
      ‘Good health for all’ and ‘employment for all’ are two widely agreed-upon goals in Norwegian politics. Nevertheless, considerable inequalities in health exist, and the economic sustainability of public pensions is pressured by a substantial increase in life expectancy. Improving our understanding of inequalities in health and the relationship between health detriments and labour market participation ...
    • Exploring the genomes of the Norwegian vancomycin resistant enterococci 

      AL-Rubaye, Mushtaq Talib Shawi (Doctoral thesis; Doktorgradsavhandling, 2023-03-24)
      Enterococci are gram-positive commensals in the human gut microbiota that may cause severe infections, especially in immunocompromised and hospitalised patients. Their ability to accumulate antimicrobial resistance and virulence genes has been vital in their evolution into leading pathogens. Vancomycin resistant enterococci (VRE) are among the most important resistant pathogens causing outbreaks ...
    • Physical activity and the structure and function of the left side of the heart 

      Heitmann, Kim Arne (Doctoral thesis; Doktorgradsavhandling, 2023-03-16)
      Current knowledge about the relationship between exercise and cardiac remodelling is mostly based on studies of athletes. Little is known about cardiac adaptations to moderate doses of exercise in the general adult and elderly population, and whether exercise-induced cardiac remodelling is a benign physiological adaption of exercise or part of a pathophysiological mechanism. The main objective of ...
    • The immune microenvironment in oral squamous cell carcinoma – characterization and prognostic markers 

      Wirsing, Anna Maria (Doctoral thesis; Doktorgradsavhandling, 2018-09-27)
      Oral squamous cell carcinomas (OSSCs) are aggressive tumors often associated with a low survival rate. The immune system influences the development of OSCCs, and the immune infiltrate surrounding the cancer cells is an indicator of the host’s anti-tumor response. The main aim of this thesis was to describe how the tumor microenvironment in OSCC is organized, and to determine whether different subsets ...
    • Regional Variation in Utilisation of Healthcare Services - A study on hospital care in Norway 

      Rudolfsen, Jan Håkon (Doctoral thesis; Doktorgradsavhandling, 2023-02-28)
      <p><i>Background:</i> In 1938, J. Alison Glover published a study on incidence of tonsillecto-mies in school children, demonstrating variation in treatment rates across school districts. Consequently, it rates raised questions as to what determines when to treat a patient. After Wennberg and Gittelsohns’ paper ‘Small Area Variations in Health Care Delivery’ was pub-lished in 1973, it became clear ...
    • Obesity-related venous thromboembolism 

      Frischmuth, Tobias (Doctoral thesis; Doktorgradsavhandling, 2023-02-22)
      Venous thromboembolism (VTE), a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common and multicausal disease. Obesity is a major and likely causal risk factor for VTE. However, to what extent obesity contributes to VTE risk in the general population and the mechanism of obesity-related VTE remain poorly understood. The overall aim of this thesis was (i) to ...
    • Cardiovascular disease: risk assessment, total risk, and primary prevention in the general population. Insights from the Tromsø Study 

      Hagen, Amalie Nilsen (Doctoral thesis; Doktorgradsavhandling, 2023-02-20)
      Cardiovascular disease (CVD) is a major cause of mortality and morbidity, calling for an active preventive approach. Elevated blood pressure and cholesterol, smoking, diabetes, unhealthy diet, inactivity, and obesity are key risk factors for CVD development. Several risk factors combined may put an individual at a high total CVD risk. To measure total CVD risk, we used the NORRISK 2 score that ...
    • Parental cognitive vulnerability during the perinatal period and its effect on mental health and the parent-infant relationship. Results from the NorBaby-study 

      Bohne, Agnes (Doctoral thesis; Doktorgradsavhandling, 2023-02-10)
      Perinatal periode er en krevende overgang i livet, som medfører økt risiko for psykiske helseutfordringer. Nedsatt psykisk helse hos foreldrene utgjør risiko for foreldre-barn relasjonen og for barnets utvikling. Gjennom samspillet med sine omsorgsgivere utvikler barnet emosjonsregulering og sosiale ferdigheter. Foreldre som blir fanget i repeterende negative tanker kan ha lite kapasitet til å plukke ...
    • Child Mental Health in Nepal. An epidemiological study of emotional and behavioral problems (EBP) among Nepali schoolchildren reported by parents and teachers 

      Ma, Jasmine (Doctoral thesis; Doktorgradsavhandling, 2023-01-20)
      <p><i>Background -</i> There is a substantial gap in our knowledge about the prevalence, magnitude, and correlates of child emotional and behavioral problems (EBPs) in Nepal. Little is known about the agreement between parent and teacher reports on EBP among Nepali children. Therefore, a large-scale survey in the general population was undertaken to fill this gap. <p><i>Methods -</i> This is a ...
    • Towards interprofessional patient care: Health profession students exploring interprofessional collaboration in group meetings in joint clinical placement 

      Gudmundsen, Anita Carin (Doctoral thesis; Doktorgradsavhandling, 2023-01-20)
      The aim of this study is to develop knowledge about how health profession students learn interprofessional collaboration in group meetings during a joint voluntary period of practice. It is an observational study. Interprofessional student groups were followed throughout a two-week practice period. The groups had a mandate to independently develop interprofessional collaboration in the healthcare ...
    • A study of occupational health among mine workers in Murmansk Oblast, Russia 

      Skandfer, Morten (Doctoral thesis; Doktorgradsavhandling, 2014-05-27)
      The mining industry is growing in the north, with the largest mining communities located in North Russia. Increased knowledge about the health and work conditions of the employees is important in order to enhance safety and prevention of ill health. The aim of the study was to describe how the health of mine workers in Murmansk oblast is assessed, determine the prevalence of low back pain (LBP) as ...