Browsing Artikler, rapporter og annet (medisinsk biologi) by Issue Date
Now showing items 101-120 of 1054
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Effect of Unfractionated Heparin on TFPI Elimination
(Journal article; Tidsskriftartikkel, 2010)Background: Tissue factor pathway inhibitor (TFPI) plays an important role for the anticoagulant effect of heparin. Depletion of intravascular TFPI by treatment with unfractionated heparin (UFH), and not by low molecular weight heparin (LMWH), has been suggested to explain the superiority of LMWH in treatment of both arterial and venous thrombosis. The present study was undertaken to investigate ... -
Vaksine og screening : ja takk, begge deler!
(Journal article; Tidsskriftartikkel, 2010-01-21)- I Norge trenger vi ikke velge mellom HPV-vaksine eller screening. Vi har råd til begge deler. -
Dekontaminering av pattedyrslakt ved bruk av damp eller varmt vann. Uttalelse fra Faggruppe for hygiene og smittestoffer i Vitenskapskomiteen for mattrygghet
(Research report; Forskningsrapport, 2010-04-15)Mattilsynet har gitt VKM i oppgave å foreta en risikovurdering når det gjelder ”dekontaminering av pattedyrslakt ved bruk av varmt vann eller damp”. Da det er en bestemtdekontamineringsteknologi Mattilsynet ønsker utredet, velger faggruppen å bruke den mer presise betegnelsen ”overflatepasteurisering av slakt” som er i tråd med uttrykk og definisjoner som forskere innenfor dette området har benyttet ... -
Chlorhexidine compounds in cosmetic products Risk assessment of antimicrobial and antibiotic resistance development in microorganisms
(Research report; Forskningsrapport, 2010-04-15)Chlorhexidine and its salts are reported as being used in cosmetics as an active ingredient to give the desired effect or as a preservative in concentrations of up to 0.3 %. Such products include mouthwashes, hair dying and bleaching formulations, shampoos, anti hair “aging” products and exfoliants, body lotions, eye creams, face cleansers, sun cream, after-sun lotions, ... -
Assessment of benefits and risks of probiotics in baby foods Bifidobacterium lactis Bb12.
(Research report; Forskningsrapport, 2010-05-14)The Norwegian Scientific Committee for Food Safety (VKM) has appointed an ad hoc-group of experts to answer a request from the Norwegian Food Safety Authority regarding benefit and risk assessment of B. lactis Bb12 in baby foods focusing on the age groups 4-6 months, 6-12 months and 1-3 years. This assessment is based on the literature provided by the notifier as well as that found by a MEDLINE search. -
Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis
(Tidsskriftartikkel; Peer reviewed; Journal article, 2010-08-10)Background: Deposition of chromatin-IgG complexes within glomerular membranes is a key event in the pathogenesis of lupus nephritis. We recently reported an acquired loss of renal Dnase1 expression linked to transformation from mild to severe membranoproliferative lupus nephritis in (NZBxNZW)F1 mice. As this may represent a basic mechanism in the progression of lupus nephritis, several aspects of ... -
Ny generasjon HPV-tester på vent
(Chronicle; Kronikk, 2010-09-18)Ny forskning viser at gentester for humant papillomvirus (HPV) siler ut de behandlingstrengende i langt større grad enn celleprøver. Samtidig er det grunn til å tro at mRNA-tester bør velges fremfor DNA-tester. -
Gene Expression, Function and Ischemia Tolerance in Male and Female Rat Hearts After Sub-Toxic Levels of Angiotensin II
(Journal article; Tidsskriftartikkel; Peer reviewed, 2010-12-19)To examine the response to chronic high-dose angiotensin II (Ang II) and a proposed milder response in female hearts with respect to gene expression and ischemic injury. Female and male litter–matched rats were treated with 400 ng kg<sup>-1</sup> min<sup>-1</sup> Ang II for 14 days. Hearts were isolated, subjected to 30-min ischemia and 30-min reperfusion in combination with functional monitoring ... -
Use of Health care in the main area of Sami habitation in Norway : catching up with national expenditure rates
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)For many years political and professional concerns have centred on the health service access of Norway’s modern Indigenous Sami people. Thirty years ago, a study determined that a low rate of health expenditure on Sami patients had lead to inferior health services for the Sami people, with their average consultation rate 6 times lower than the Norwegian national average. Since 1980, there have been ... -
Does long-term care use within primary health care reduce hospital use among older people in Norway? A national five-year population-based observational study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Population ageing may threaten the sustainability of future health care systems. Strengthening primary health care, including long-term care, is one of several measures being taken to handle future health care needs and budgets. There is limited and inconsistent evidence on the effect of long-term care on hospital use. We explored the relationship between the total use of long-term care within public ... -
Premature cardiovascular mortality and alcohol consumption before death in Arkhangelsk, Russia : an analysis of a consecutive series of forensic autopsies
(Journal article; Tidsskriftartikkel, 2011)High CVD mortality among the middle-aged is a major cause of low life expectancy in Russia, especially among men. Hazardous alcohol consumption is suspected to be a powerful factor. All men (1099) and women (519) who died between 01.01.08 and 31.08.09 from cardiovascular disease at ages of 30-70 years in the city of Arkhangelsk, Northwest Russia, were included. CVD mortality was stratified by age, ... -
A Genome-Wide Association Study of Upper Aerodigestive Tract Cancers Conducted within the INHANCE Consortium
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Genome-wide association studies (GWAS) have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation involved in susceptibility to upper aero-digestive tract (UADT) cancers. Genome-wide genotyping was carried out using the Illumina HumanHap300 beadchips in 2,091 UADT cancer cases and ... -
Prognostic Impact of Lymphocytes in Soft Tissue Sarcomas
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)The purpose of this study was to clarify the prognostic significance of lymphocyte infiltration in soft tissue sarcomas (STS). Prognostic markers in potentially curable STS should guide therapy after surgical resection. The immune status at the time of resection may be important, but the prognostic significance of tumor infiltrating lymphocytes is controversial as the immune system has conflicting ... -
Quality registry for improving the quality and relevance of higher education in Pakistan
(Journal article; Tidsskriftartikkel, 2011) -
Fibroblast growth factor 2 orchestrates angiogenic networking in non-GIST STS patients
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Non-gastrointestinal stromal tumor soft-tissue sarcomas (non-GIST STSs) constitute a heterogeneous group of tumors with poor prognosis. Fibroblast growth factor 2 (FGF2) and fibroblast growth factor receptor-1 (FGFR-1), in close interplay with platelet-derived growth factor-B (PDGF-B) and vascular endothelial growth factor receptor-3 (VEGFR-3), are strongly involved in angiogenesis. This study ... -
Sex hormones and gene expression signatures in peripheral blood from postmenopausal women - the NOWAC postgenome study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011) -
The prognostic impact of Akt isoforms, PI3K and PTEN related to female steroid hormone receptors in soft tissue sarcomas
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)The PI3K/Akt pathway is involved in cellular survival pathways by inhibiting apoptotic processes and stimulating cell growth and proliferation. Its negative prognostic value has been proven in many types of cancer. In soft tissue sarcomas, the expression profiles of the PI3K/Akt pathway components are poorly defined and their significance uncertain. We aimed to investigate the prognostic impact of ... -
The Prognostic Impact of TGF-beta 1, Fascin, NF-kappa B and PKC-zeta Expression in Soft Tissue Sarcomas
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Transforming growth factor-β (TGF-β), fascin, nuclear factor-kappa B (NF-κB) p105, protein-kinase C-zeta (PKC-ζ), partioning-defective protein-6 (Par-6), E-cadherin and vimentin are tumor promoting molecules through mechanisms involved in cell dedifferentiation. In soft tissue sarcomas, their expression profile is poorly defined and their significance is uncertain. We aimed to investigate the ... -
Precaution or Integrated Responsibility Approach to Nanovaccines in Fish Farming? A Critical Appraisal of the UNESCO Precautionary Principle
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)Nanoparticles have multifaceted advantages in drug administration as vaccine delivery and hence hold promises for improving protection of farmed fish against diseases caused by pathogens. However, there are concerns that the benefits associated with distribution of nanoparticles may also be accompanied with risks to the environment and health. The complexity of the natural and social systems involved ... -
Parity and total, ischemic heart disease and stroke mortality. The Adventist Health Study, 1976-1988
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011)In a prospective study with information about life style and reproductive factors, we assessed the relationship between parity and total, ischemic heart disease, and stroke mortality. The large majority of the 19,688 California Seventh-day Adventist women included did not smoke or drink alcohol, 31 percent never ate meat and physical activity was relatively high. Cox proportional hazard analysis ...